Sentences with phrase «of urokinase»
Itoh et al. «Inhibition of Urokinase Receptor (uPAR) Expression by RNA - Cleaving Catalytic DNA (DNAzyme) Containing Antisense uPAR», Molecular Therapy, 5 (5): S134, 2002.
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Figure 8 (C) shows that kahweol - treatment induces a dose - dependent decrease in the levels of urokinase in HUVEC conditioned media, with an almost complete inhibition at 50 µM kahweol.
Urokinase (uPA): The αMUPA mouse lineage has the addition of a urokinase gene and has a longer life span as a result.
Thrombosis recanalization by paeoniflorin through the upregulation of urokinase - type plasminogen activator via the MAPK signaling pathway.
Not exact matches
Everyone has urokinase plasminogen activator receptor (uPAR), a healthy molecule «tethered» in place to various types of cells.
This protease activates hepatocyte growth factor (HGF) and urokinase plasminogen activator (uPA), two proteins thought to be involved in the growth and motility of cancer cells, particularly carcinomas, and in the vascularization of tumors.
Urokinase - type plasminogen activator receptor regulates a novel pathway of fibronectin matrix assembly requiring Src - dependent transactivation of epidermal growth factor receptor.
They include its effects on endothelial cell «differentiation» to yield tubular - like structures, endothelial and tumor cell proliferation, apoptosis, and migration, as well as its effects on extracellular matrix remodelling enzyme activities of matrix metalloproteinase - 2 (MMP - 2) and urokinase - type plasminogen activator (uPA).
Our results in the zymographic assays for gelatinase and urokinase activities clearly showed that, in fact, kahweol was able to inhibit the expression of both MMP - 2 and uPA, identifying them as two relevant molecular targets for kahweol.
In addition, it also enhances the body's production of both plasmin and other clot - dissolving agents, including urokinase (endogenous).
Urokinase comes along, carried on the surface of platelets and certain white blood cells, to finish the job.