Sentences with phrase «of vaccine candidates»

This new mouse model should be useful for comparative assessments of the large range of vaccine candidates now being designed.

Results from the RV172 study of a vaccine candidate in East Africa conducted by MHRP were published recently in the Journal of Infectious Diseases 2010 Jan 11.

Preclinical studies of vaccine candidates have typically shown post-infection virologic control, but protection against acquisition of infection has previously only been reported using less rigorous viral challenges.

They have been actively involved in finding immune correlates of protection, implementation of new TB vaccines and testing of vaccine candidates in murine models.

Importantly, the animals in this model develop broadly neutralising antibodies over successive episodes of placental malaria, as do women, suggesting that this may be an appropriate model for preclinical qualification and down selection of vaccine candidates.

The Walter Reed Army Institute of Research (WRAIR) began vaccinations today in a Phase 1 clinical trial to evaluate the safety and immune response of a vaccine candidate to prevent Middle East Respiratory Syndrome (MERS).

The panel discussed progress that's been made including the follow - up to the RV144 Thai prime - boost trial results and in the development of the next generation of vaccine candidates for testing.

One potential use of the vaccine candidate Stamatatos is developing would be to combine it with this or other vaccine candidates, adding to the effect of each.

This can inform and accelerate the development of new vaccines, especially important during outbreaks and epidemics when clinical testing of vaccine candidates need to be fast tracked.

The Pilot Bioproduction Facility headed by Dr. Kenneth H. Eckels, produced small batches of vaccine candidates that were used for the preclinical studies and is currently manufacturing a vaccine lot for use in initial human clinical studies.

The protein fragment of the vaccine candidate comes from gp120, a protein that covers HIV like a protective envelope.

«But the ability of the vaccine candidate to raise substantial antibodies against the sugar shield in only two months is encouraging; other studies took up to four years to achieve similar results.

Phase IIb trial - A Phase 11b or test - of - concept trial is about finding out if the vaccine concept or the type of vaccine candidate being tested will be effective.

Creating an environment to accelerate the development and clinical assessment of vaccine candidates for diseases of poverty

This has resulted in the majority of vaccine candidates identified either in rodent models or as the targets of commonly developed antibodies in highly exposed humans.

In parallel, scientists with the P5 have been developing, analyzing and selecting protein components of the vaccine candidates for use in planned studies.

To fill and diversify the pipeline of vaccine candidates and strategies, TBVI aims to support 20 approaches, focusing on:

Ownership of vaccine candidates and biomarkers and any intellectual property rights remain with researchers and vaccine developers.

His approach allows researchers to quickly screen dozens, even hundreds, of vaccine candidates in the lab and — without having to inject a single person — throw out the ones that don't have a chance of working.

The Walter Reed Army Institute of Research (WRAIR) began vaccinations today in a Phase 1 clinical trial to evaluate the safety and immune response of a vaccine candidate to prevent Middle East... Read More

That gave us the idea of using a similar approach for the generation of vaccine candidates for the prevention of CIV, and our initial data using the mouse model of influenza infection support the usefulness of this approach.

Jeff Currier presented data from a Phase I study of a vaccine candidate that was developed by MHRP.

Sophie joined EVI in January 2010, and is responsible for overseeing pharmaceutical and subsequent production of vaccine candidates, as well as ad hoc clinical development.