Sentences with phrase «of validation of the model»

They found that genes activated in the mouse model closely mirrored genes known to be activated in infected humans, providing a level of validation of the model.

«It's sort of a validation of the model we chose, which was to do something outside of the publisher model, taking all the risk ourselves, putting our own money into it.

Not exact matches

Having people buy your product is the ultimate validation of your business model, he says.

But it's also interesting as validation of a model that's becoming increasingly popular: Companies that are private only in name.

«It's a validation of the fact that our model works,» CEO of HTT Dirk Ahlborn told Wired.

The results were a validation of Jeff Bezos's customer - centric philosophy and the Amazon Prime membership model, sending the shares up the most in almost a year Friday morning.

Cryptocurrency mining itself refers to a type of validation model known as «proof - of - work» (PoW).

A range of factors have driven this shift, including a sharp reduction in the cost to advance technology companies to proof of concept and business model validation — aided by declining infrastructure expenses, the rise of cloud - based software and service providers, and «pay as you grow» cost structures.

In the customer development process at the end of customer validation the business model is verified.

Essentially startups need to «instrument» all parts of their business model to measure how well their hypotheses in Customer Discovery and Validation are faring in the real world.

Highland Capital's commitment to acquire the Series A preferred stock, combined with a sizeable position they have acquired in the common stock, has provided further institutional validation of JCAP's business model.

Teams organically form around the top ideas (as determined by popular vote) and then it's a 54 hour frenzy of business model creation, coding, designing, and market validation.

The objective of this customer validation process is to validate your sales process and the assumptions that underpin your business model.

The «customer validation» process described by Steven Blank in his book, The Four Steps to the Epiphany, offers startups a way of developing the insights required to design your business model using Osterwalder's Business Model Camodel using Osterwalder's Business Model CaModel Canvas.

«HealthKick recognition was an important validation of our technology and business model,» said Dr. Don Stewart, PlantForm President and CEO.

Several lenders and service providers in connection with the design and validation of lending and consumer scoring models.

See Ricoeur's discussion of the problem of validation vis a vis Hirsch in «The Model of the Text», op.cit.,158 - 162.

After an extensive content validation process, including expert panel review by all Steering Committee members and all work group members, the final instrument included 130 core items that collected information on demographics, access to maternity care, preferences for model of care, maternal and newborn outcomes, knowledge of midwifery care, and experience of care including the process of decision - making.

The Warren gap is both a validation of dynamic solar system models that predict a similar scenario, and a constraint they must reckon with, says Kevin Walsh, a SwRI dynamicist.

Based on their findings, they urge that «mosquito saliva and enhancing antibodies thus need to be considered when developing vaccines and drugs against dengue,» and specifically suggest that «animal models of dengue and pre-clinical validation of dengue vaccine candidates should be evaluated in the combined presence of mosquito saliva and enhancing antibodies.»

He is the director of its «global validation model.»

The new technique could provide a much - needed experimental validation of frequently used computational models, as well as a means of investigating the effect of new battery materials and additives on lithium metal plating.

Using the calibrated models, the researchers then applied NIRS to a random mix of mosquitoes and checked the results against validation tests using mosquito extracts for molecular detection of strain - specific Wolbachia DNA to determine accuracy.

From accelerating the identification and validation of novel therapeutic targets, to creating better animal models of human diseases in a shorter time frame, to reducing the number of failed products, Crispr looks set to shave millions off R&D costs and boost drug discovery, she says.

Historian of science Naomi Oreskes, now at Harvard, first came to my attention 20 years ago, when she and two co-authors argued in Science that «verification and validation of numerical models of natural systems is impossible.»

Any results that are reported to constitute a blinded, independent validation of a statistical model (or mathematical classifier or predictor) must be accompanied by a detailed explanation that includes: 1) specification of the exact «locked down» form of the model, including all data processing steps, algorithm for calculating the model output, and any cutpoints that might be applied to the model output for final classification, 2) date on which the model or predictor was fully locked down in exactly the form described, 3) name of the individual (s) who maintained the blinded data and oversaw the evaluation (e.g., honest broker), 4) statement of assurance that no modifications, additions, or exclusion were made to the validation data set from the point at which the model was locked down and that neither the validation data nor any subset of it had ever been used to assess or refine the model being tested

Diamond is also quick to point out that while the current study shows that COXEN could have been used to predict the most useful drug in many of these cases of advanced ovarian cancer, the actual use of the model will be possible only after validation with a prospective clinical trial.

The researchers also tested their prediction models on the validation set, and this resulted in ROC (receiver operating characteristic) plot points with an AUC (area under the curve) of 91.6 percent for general responsiveness, 89.7 percent for TNFi response and 85.7 percent for rituximab response.

They used 70 percent of the samples to develop response prediction models, and reserved 30 percent for validation.

The specific goal of releasing space - weather data from national - security assets such as GPS satellites is to enable broad scientific community engagement in enhancing space - weather model validation and improvements in space - weather forecasting and situational awareness.

So the more that we can understand the human validation of our targets and perhaps even build model systems that take advantage of human biology,» the better off we'll be, he says.

Validation of its high - fidelity model and the predictive accuracy of its new simulation methods are giving GE the ability to better integrate simulation directly into its product design cycle.

«Once the in - vitro validation has been done, the efficacy of these compounds will be tested in pig and mouse models.

«In this manner, we'll help propel the community to develop microstructure - sensitive materials models and provide the validation needed to push materials to the next level of performance.»

[2] Lipid method Chunxiu Hu et al., RPLC - Ion - Trap - FTMS Method for Lipid Profiling of Plasma: Method Validation and Application to p53 Mutant Mouse Model.

IDMIT will contribute 1) To the development and validation of assays based on flow cytometry and mass cytometry for the evaluation of immune responses in humans and animal models; these tools will be particularly relevant for the identification of signatures of vaccine efficacy; 2) To the animal model platform, in particularly by providing access to NHP models and to new technologies for in vivo imaging infections and host responses; 3) To networking activities, in particular by organising a workshop on in vivo imaging.

Validation and testing of this model for a number of research questions related to treatment of stress urinary incontinence are under way.

For each IAT, the authors examined their technological type, application, target population, model... of development, and evidence of clinical validation.

Our goal is to help scientists who want to use this technology for gene editing by summarizing current advances on many technical aspects, from the RNA guide optimized design to the genotyping analysis and the validation of the newly generated models.

I can read any peer - reviewed article I like on modern climate models, but until I go through much of the process of building, running, validation, discussing with colleagues how they solved particular wrinkles etc of some models, I am unlikely to fully comprehend climate modelling as a skilled craft.

The Genetic Engineering and Model Validation department is in charge of the generation of customized and ready - to - use genetically modified mouse.

The Ospedale San Raffaele Mouse Clinic (OMC) is the follow - up and consolidation of a Regione Lombardia - funded project (EMDM), which aimed at the establishment and implementation of a large, dedicated facility (the European Mouse Disease Models Center) whose goal is the development and functional assessment of mouse disease models, both for the dissection of the underlying pathogenic mechanisms and for the screening and validation of innovative diagnostic and therapeutic proceModels Center) whose goal is the development and functional assessment of mouse disease models, both for the dissection of the underlying pathogenic mechanisms and for the screening and validation of innovative diagnostic and therapeutic procemodels, both for the dissection of the underlying pathogenic mechanisms and for the screening and validation of innovative diagnostic and therapeutic procedures.

Development of efficient SB based models of inference and validation techniques (UNISI, ETHZ).

OMC is a scientific and technological platform aimed at supporting R&D activities related to the validation and use of mouse models of human disease.

Lab experiments to confirm the activity of multiple neoantigens are time consuming, and current computer models to predict antigenicity can be inaccurate due to low validation.

Position Description: The University of Vigo offers a Research Position in Vigo (Spain) to work with the Laboratory of Remote Sensing and GIS on the H2020 research project CoastObs in validation of Sentinel 3 data in order to provide information about the relationship between environmental conditions in HABs blooms and develop of local CASE 2 chl - a models.

No climate model has ever been properly tested, which is what «validation» means, and their «projections» are nothing more than the opinions of «experts» with a conflict of interest, because they are paid to produce the models.

«This is the first biological validation of a computational model developed in the early 1980s that suggested that two such forces would be necessary to guide axons as they establish the connections that relay spatial information from one part of the nervous system to another,» said study author Yimin Zou, PhD, assistant professor of neurobiology at the University of Chicago.

For a given tissue, we perform 3 - repeat -5-fold cross validation with the samples corresponding to the individuals of the training block in order to select the best model, and we generate the predictions over the unseen test set using this model.

Genetic Engineering and Model Validation: engineering and generation of customised genetically modified mouse models, generation of genetically modified ES cells, genotyping, analysis of gene expression, model validation by molecular analysis, CRISPR / Cas9 nucleases technModel Validation: engineering and generation of customised genetically modified mouse models, generation of genetically modified ES cells, genotyping, analysis of gene expression, model validation by molecular analysis, CRISPR / Cas9 nucleases Validation: engineering and generation of customised genetically modified mouse models, generation of genetically modified ES cells, genotyping, analysis of gene expression, model validation by molecular analysis, CRISPR / Cas9 nucleases technmodel validation by molecular analysis, CRISPR / Cas9 nucleases validation by molecular analysis, CRISPR / Cas9 nucleases technology