Sentences with phrase «of vascularized»

«3D Microfluidic Models of the Vascularized Tumor Microenvironment: Advancing Precision Medicine and Understanding Collective Migration»

These different mechanisms all allowed for the process of self - assembly of vascularized liver organ buds involving spatial rearrangements via self - organization.

Generation of a vascularized and functional human liver from an iPSC - derived organ bud transplant.

Not exact matches

«I think the bigger picture here is in vascularized solids, ones that are kind of like tissues with vascular networks.

In September, George Church of Harvard Medical School — it was he who delayed trying to give brain organoids a blood supply — told a small meeting that his lab had vascularized brain organoids.

The penis, he reasoned, is highly vascularized, «like a great big sponge» of blood vessels.

Review of «Vascularized and Complex Organ Buds from Diverse Tissues via Mesenchymal Cell - Driven Condensation» from Cell Stem Cell by Stuart P. Atkinson

A. Mansour et al., «An in vivo model of functional and vascularized human brain organoids,» Nat Biotechnol, doi: 10.1038 / nbt.4127, 2018.

Researchers from the laboratories of Hiroshi Y. Yoshikawa and Hideki Taniguchi had previously demonstrated the in vitro formation of a 3D transplantable liver «organ bud» from human induced pluripotent stem cells (iPSCs) co-cultured with mesenchymal and endothelial progenitors, and allows for the growth of a small vascularized and functional organ [1 - 3].

Now, in a new study in Cell Stem Cell, the group have begun to delineate the mechanisms controlling organ bud formation, and from these findings they have been able to describe a general methodology for the formation of large vascularized, complex organ buds from diverse organs using specific stem cell combinations [4].

Chairs: Elena Aikawa, Brigham and Women's Hospital / Harvard Medical School and Anjelica Gonzalez, Yale University Christopher Hughes, University of California, Irvine Vascularized and perfused micro-tissues in culture and their use in drug screening Ying Zheng, University of Washington Engineering organ - specific microvasculature

The failure in pancreatic cancer treatment is main due to the presence of a dense and poorly vascularized stroma that increase the drug clearance in the tumors rather than the healthy tissues, decreasing drug bioavailability in the target tissue and leading to significant side effects.

A team at the Harvard John A. Paulson School for Engineering and Applied Sciences (SEAS) and the Wyss Institute for Biologically Inspired Engineering at Harvard University has invented a method for 3D bioprinting thick vascularized tissue constructs composed of human stem cells, extracellular matrix, and circulatory channels lined with endothelial blood vessel cells.

Furthermore, when the authors assessed the subcutaneous implantation of hDPSCs grown on CPD scaffolds, they discovered that PDGF - BB modified cells generated more dentin - like mineralized tissue surrounded by highly vascularized dental pulp - like connective tissue at 12 weeks when compared to unmodified hDPSCs.

For the first time, researchers describe the formation of entirely hPSC - derived 3D muscle tissues that survive, vascularize, and maintain function following transplantation

However, researchers from the laboratory of Nenad Bursac (Duke University, Durham, NC, USA) have recently described the production and differentiation of induced myogenic progenitor cells (iMPCs) from hPSCs into the first entirely hPSC - derived 3D muscle tissues that survive, vascularize, and maintain function following transplantation [5].

«The foreskin contains over 240 feet of nerves and over 1,000 nerve endings, as well as being a highly vascularized structure.»

At the Beth Israel Medical Center both surgeons transfer vascularized lymph nodes from an healthy area of the body to the area affected with lymphedema.

And both of those have been looked at in studies in terms of their ability to show new bone formation or to vascularize the connective tissue.