In veterinary medicine, the use
of vasopressors and inotropic drugs is preferred before risking injury with high volumes of crystalloids and HES.11
Cytokine release syndrome occurs when many cytokines get released into the serum upon CAR T - cell injection; patients can get high fevers and sometimes hypertension, and occasionally there is a need for mechanical ventilation or administration
of vasopressors, but that is rare.
Not exact matches
They found that patients from this group who required admission to intensive or critical care units after surgery were more likely to have a history
of chronic obstructive pulmonary disease, congestive heart failure, coronary artery disease, chronic kidney disease, or suffering blood loss
of more than 1,000 milliliters during surgery or requiring
vasopressors (medications that raise low blood pressure) during surgery.
The study enrolled 321 patients — 163 treated with angiotensin II and 158 with placebo — who were experiencing vasodilatory shock and had received high doses
of conventional
vasopressors.
When the condition is not responsive to high - dose
vasopressors like norepinephrine and vasopressin, it is associated with high mortality, with more than half
of these patients dying within 30 days,» Dr. Khanna said.
Norepinephrine is recommended as the first - line
vasopressor (a drug that constricts [narrows] blood vessels, increasing blood pressure) for treatment
of hypotension (abnormally low blood pressure) due to septic shock.
In ZUMA - 1, 12 %
of the patients had a grade 3 or higher cytokine release syndrome and that is essentially a patient requiring mechanical ventilation or needing treatment with a high - dose
vasopressor.
This lecture will demystify the use
of adrenergic and non-adrenergic
vasopressors and help identify what patients may benefit from pressors (as early as the emergency department), current recommendations from the human field, and how to be practical in pressor use and patient monitoring.
Management and titration
of multiple intravenous medications, to include
vasopressors, sedatives, and pain control devices
For patients with suspected infection within the ICU, the SOFA score had predictive validity (AUROC = 0.74; 95 % CI, 0.73 - 0.76) superior to that
of this model (AUROC = 0.66; 95 % CI, 0.64 - 0.68), likely reflecting the modifying effects
of interventions (eg,
vasopressors, sedative agents, mechanical ventilation).