Shoukhrat Mitalipov of Oregon Health and Science University led research in which scientists edited the DNA
of viable human embryos.
Using the gene - editing tool known as CRISPR / Cas9, the researchers have successfully edited disease - causing mutations out
of viable human embryos.
In a step that some of the nation's leading scientists have long warned against and that has never before been accomplished, biologists in Oregon have edited the DNA
of viable human embryos efficiently and apparently with few mistakes, according to a report in Technology Review.
In July, researchers announced they had successfully edited the genome
of viable human embryos with CRISPR; the technique allowed them to fix a disease - causing mutation in the embryos» DNA (though some are now skeptical of the researchers» results).
But in March, Lichun Tang of China's Beijing Proteome Research Center and colleagues reported using CRISPR / Cas9 to correct disease - causing mutations in a small number
of viable human embryos.
Not exact matches
There should be a complete ban on the implantation
of a
human embryo created by the application
of cloning technology into a womb, or any treatment
of such a
human embryo intended to result in its development into a
viable infant.
They've certainly been successful in making their voices heard in recent years — for example, over the question
of what to do with the 400,000 frozen
human embryos left over from in vitro fertilization with no
viable future.
The first results
of gene editing in
viable human embryos reveals it works better than we thought, but that there's another big problem blocking the way
If the cells can be fertilized and develop into
viable embryos, and if
human ES cells turn out to have similar powers, such cells could allow researchers to get around some
of the expense and ethical questions that arise from using donated eggs for therapeutic cloning experiments.
Our No. 2 story, on gene editing in
viable human embryos, reminds us
of the many intricacies
of human biology.
But, after researchers at Oregon Health and Science University managed to change the mutated version
of the MYBPC3 gene to the unmutated version in a
viable human embryo last month, the predictable bioethical debate was reignited, and terms such as «Designer Babies» got thrown around a lot.