Sentences with phrase «of viral epidemics»

A cast consisting of Dustin Hoffman, Kevin Spacey, Rene Russo, Donald Sutherland and Morgan Freeman battled for mankind's survival against the spread of a viral epidemic.

Not exact matches

Meantime there's always the risk of antibiotic - resistant bacteria, plus the perpetual risk of a lethal viral epidemic.

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

Social posts have been going viral to the point of epidemic.

Determining whether individual mutations are deleterious, or even adaptive, would require functional analysis; however, the rate of nonsynonymous mutations suggests that continued progression of this epidemic could afford an opportunity for viral adaptation (Fig. 4H), underscoring the need for rapid containment.

The epidemic strain produced elevated amounts of subgenomic flavivirus RNA (sfRNA), a viral noncoding RNA, relative to amounts of genomic viral RNA.

The global spread of dengue virus (DENV) infections has increased viral genetic diversity, some of which appears associated with greater epidemic potential.

In addition to this, there was a drastic drop in the number of specimens in the 20th century due to its persecution, the destruction of its habitat, and two major viral epidemics suffered by the rabbit, its main food source.

The human outbreaks consisted of multiple simultaneous epidemics caused by different viral strains, and each epidemic resulted from the handling of a distinct gorilla, chimpanzee, or duiker carcass.

With viral epidemics such as AIDS taking a huge toll, insect - borne diseases have been «pretty far back on the burner» in New York, says John Edman, director of the Center for Vector - Borne Disease Research at the University of California, Davis.

«We knew it was important to understand the viral populations driving the epidemic, which motivated us to tackle the challenges of sequencing Zika,» said study co-first author Hayden Metsky, a graduate student in the Sabeti lab.

Other viral diseases spread by the same mosquitoes — including dengue and chikungunya — that have caused massive epidemics south of the U.S. border have triggered only small outbreaks in the United States.

«As the next epidemic or viral threat comes up — for example, the next Zika or Ebola — we think there's a lot of utility in using this for better surveillance for those outbreaks,» says Jonathan Gootenberg, another team member.

A family friend, veterinary pathologist Sharad Ajinkya, mentioned that he'd been studying a viral epidemic that was sweeping through poultry flocks, killing hundreds of thousands of chickens.

«Bringing the global HIV epidemic under control requires new tools, bold strategies and collaboration among a number of stakeholders,» said Hanneke Schuitemaker, one of the study authors and vice president, Viral Vaccines Discovery and Translational Medicine, Janssen.

In addition, the strain isolated from lions and hyenas during the 1993/1994 epidemic had rare mutations in two viral proteins: the CDV - H protein, which binds to the host cell receptor (called SLAM CD 150) and therefore plays an important role to facilitate viral entry into host cells, and the CDV - V protein, which enables the virus to manipulate the innate immune response of the host.

UNAIDS modeling shows that epidemics will peter out if 90 % of infected people know their HIV status, 90 % of that group receive antiretrovirals, and 90 % on treatment have undetectable viral levels.

Most of his research has focused on reovirus, an important experimental model for studies of viral encephalitis in the young, and chikungunya virus, an emerging mosquito - borne virus that causes epidemics of fever and arthritis.

For the study, the team analyzed viral genomic sequences from 232 patient samples collected over the 7 - month spread of the disease in Sierra Leone, along with 86 genome sequences reported earlier in the epidemic.

«The authors reach the interesting conclusion that it might be possible for vaccines with certain profiles to affect the transmission and evolution of influenza viruses and that, theoretically, universal vaccines could control influenza epidemics while slowing the rate of viral evolution.

His research includes (i) the molecular epidemiology and epidemic history of HIV and hepatitis C, particularly in Asia and Africa, (ii) the global evolution of influenza viruses, (iii) virus and immune dynamics during chronic viral infection, (iv) the evolution of flaviviruses, and (v) the development of new techniques for tracking and predicting virus transmission.

The ability to sequence DNA outside of the laboratory setting has enabled novel research questions to be addressed in the field in diverse areas, ranging from environmental microbiology to viral epidemics.

An international effort to analyze the entire database of Ebola virus genomes from the 2013 — 2016 West African epidemic reveals insights into factors that sped or slowed the rampage and calls for using real - time sequencing and data - sharing to contain future viral disease outbreaks.

Dr Stephen Buhner mentions in his book the more virulent and deadly viral illnesses such as the 1918 influenza epidemic are so dangerous because of the viral induced «cytokine storm», a severe inflammatory response which overwhelms and kills the patient.

In fact, the viral piece of the puzzle may have played a far bigger role in the worldwide obesity epidemic than anyone wishes to imagine.

There's little doubt that Isolation opens with a fair degree of promise, as filmmaker Stephen Kay kicks off the proceedings with a 28 Days Later - like stretch in which Amy attempts to figure out just what's going on - with her confusion and terror amplified by radio reports of a worldwide viral epidemic.

Our hero, Dr. Nathaniel (Nate) McCormick, describes himself as «an officer in the Epidemic Intelligence Service, a branch of the Centers for Disease Control and Prevention... part of the Special Pathogens Branch, which is in the Division of Viral and Rickettsial Diseases».

Because of this, animal shelters, feral cat colonies, and any other large group of cats are at the highest risk of housing viral or bacterial infection epidemics.

It's not an epidemic of viral disease, but of chronic ill health.

Chadwick's Viral Landscapes (1989 - 90), made at the height of the Aids epidemic, connect the changes in her body with those of the wave - shattered shoreline, superimposing outsize photographs with magnified images of the artist's cellular tissue in a sweeping panorama of time and tide.

• Successfully created and implemented a series of care plans during the epidemic breakout of a viral infection in June 2011.