The aims of the study are 1) to investigate differences in the topographic distribution
of white matter integrity between adolescents with IAD and healthy controls without IAD, making no a priori assumptions about the location of possible abnormalities, and 2) to determine whether there was any relationship between white matter integrity and neurophysiological measures in IAD subjects.
Goldstein and her colleagues found that patients diagnosed with â $ œamnesticâ $ MCI showed greater loss
of white matter integrity in a certain part of the brain — the medial temporal lobe â $ «than cognitively normal controls of similar age.
«We retrospectively analyzed the data from the DTI sequence to derive measures
of white matter integrity, which we compared to clinical measures and subsequent outcome measures 6 months to 2.5 years after the initial evaluation.»
In particular, loss
of white matter integrity has a direct, measurable effect,» Dr. Ware said.
«It was illuminating to see the association between measures
of white matter integrity and important outcomes occurring months to years down the road in our study population.»
Not exact matches
If fallenness can be attributed to the arrival
of white settlers, and the «creation» has its own
integrity rather than intrinsic brokenness, redemption becomes a
matter of human effort and re-education.
A prospective study
of physician - observed concussion during a varsity university hockey season:
white matter integrity in ice hockey players.
In addition, brain imaging studies in rats and humans have shown alterations in gray
matter volume and
white matter integrity in the brain caused by the effects
of chronic pain.
For the new study, researchers from the University
of Pittsburgh Medical Center (UPMC) in Pittsburgh used diffusion tensor imaging (DTI), an MRI technique that measures the
integrity of white matter — the brain's signal - transmitting nerve fibers — to see if injuries to the nerves may be the root cause
of these post-traumatic depression and anxiety symptoms.
Compared to controls, patients with depression had decreased fractional anisotropy (FA), a measure
of the structural
integrity of white matter connections, around an area near the deep gray
matter of the brain that is strongly associated with the brain's reward circuit.
In a new study published in the journal Neuropsychopharmacology, neuroscientists from the University
of Chicago show that
white matter in a region
of the brain called the superior longitudinal fasciculus (SLF) has less
integrity and density in people with IED than in healthy individuals and those with other psychiatric disorders.
«Connection between
integrity of brain's
white matter, cognitive health.»
Previous research has showed that musicians have increased
white matter integrity in a specific part
of the brain called the corpus callosum, a thick band
of nerve fibres that connects the left and right halves
of the brain, enabling communication between the hemispheres.
When the investigators analysed MRI studies
of the brain, they found that participants with MCI, particularly those with non-amnestic MCI, had larger
white matter lesion volumes and worse microstructural
integrity of normal - appearing
white matter compared to controls.
If musical aptitude increases the
white matter integrity of the corpus callosum, musical training could potentially counteract an individual's predisposition
of hallucinations.
«From the MRI we learned
of a recovery mechanism in that neural stem cell therapy improves
white matter integrity,» said Baker.
The researchers found cardiorespiratory fitness was positively linked to the structural
integrity of white matter fiber bundles in the brain in the older adults, while no such association was observed in younger adults.
Their responses on these facial affect recognition tasks were correlated with neuroimaging changes on diffusion tensor imaging (DTI), which shows the
integrity of white matter tracts in the brain.
Patients with schizophrenia, bipolar disorder and their unaffected relatives show
white matter density and
integrity reductions in the anterior limb
of the internal capsule (ALIC).
In this diffusion tensor imaging (DTI) study, the authors investigated
white matter integrity in schizophrenia and the relationships between
white matter alterations and specific symptoms
of the
When compared to the control group, type 2 patients showed decreased
integrity in the
white matter of two different areas in the brain — the cingulum bundle, which is a fiber tract that connects regions in the default - mode network, and the uncinate fasciculus, which connects regions important for executive function and memory.
It examines diffusion tensor imaging as a way to probe the
integrity of the brainâ $ ™ s
white matter, and compares it with tests
of memory and behavior traditionally used to diagnose MCI and Alzheimerâ $ ™ s.
Here the authors try combining probing
white matter integrity with a MRI measure
of whether the brain has shrunk as a result
of disease.
Effects
of systolic blood pressure on
white -
matter integrity in young adults in the Framingham Heart Study: a cross-sectional study
Generally, DTI studies have used fractional anisotropy (FA) as a general index
of white -
matter microstructural «
integrity».