Sentences with phrase «offspring of an affected dog»

Each affected dog has at least one affected parent, but it can be expected that half of the offspring of an affected dog will be free of the defective gene.

Roughly the same situation occurs with a dominant disease that has a post - reproductive age of onset, since as many as half of the offspring of an affected dog will become afflicted in their lifetime, but not until they have passed on the disease gene to half of their offspring.

Most veterinarian suggest not to breed affected dogs, their parents, siblings of affected dogs, as well as offspring of affected dogs.

Parents, full or half siblings, and offspring of an affected dog should also be bred to mates from families free of moderate to severe allergies.

The lesson here is that the only dogs whom we can say are carriers, are those who have produced affected dogs, or are the offspring of affected dogs.

There is no test for carriers, or way to identify carriers of CA, unless they produce an affected dog, or are the offspring of an affected dog.

Not exact matches

Owners or adopters of non-purebred dogs can also help by sterilizing their pets before they become sexually mature to prevent any possibility of producing affected offspring.

Stud Dog owners should disclose to owners of bitches who wish to use their dog that the dog is a known carrier (by virtue of it being out of an affected parent or having itself sired affected offspring, or by virtue of it having been genetically identified as a carrier for the Cord1 mutation), even though the Stud Dog may himself have a current clinically clear eye certificaDog owners should disclose to owners of bitches who wish to use their dog that the dog is a known carrier (by virtue of it being out of an affected parent or having itself sired affected offspring, or by virtue of it having been genetically identified as a carrier for the Cord1 mutation), even though the Stud Dog may himself have a current clinically clear eye certificadog that the dog is a known carrier (by virtue of it being out of an affected parent or having itself sired affected offspring, or by virtue of it having been genetically identified as a carrier for the Cord1 mutation), even though the Stud Dog may himself have a current clinically clear eye certificadog is a known carrier (by virtue of it being out of an affected parent or having itself sired affected offspring, or by virtue of it having been genetically identified as a carrier for the Cord1 mutation), even though the Stud Dog may himself have a current clinically clear eye certificaDog may himself have a current clinically clear eye certificate.

This dog will be affected and will and will always pass a copy of the mutation to its offspring.

First - step relatives (parents, full and half siblings, and offspring if any) of affected dogs who will be used for breeding should be tested.

If screening detects that a dog is predisposed to a genetic disease (or likely to produce affected offspring) and / or perhaps already in the early stages of the disease, then no breeding can take place under the scheme.

In addition, don't breed offspring or littermates of affected dogs.

However, looking at our square we know that some of these «normal» dogs actually have a phenotype of Pp, meaning that they are PRA carriers, and can pass the PRA affected gene to their offspring.

In order to avoid producing crd2 - affected offspring, at least one dog of any breeding pair should be homozygous Normal / Clear (See chart below).

They are in need of blood samples from PRA affected dogs, their littermates, parents and / or offspring.

The dog is affected, and will always pass a copy of the mutated gene to its offspring.

The dog is affected and will always pass a copy of the mutation to its offspring.

In order to avoid producing affected offspring, carriers of the rcd1b mutation should never be bred to other carriers or to affected dogs (see chart below).

The scale of liability (standard deviation from threshold) within the population of dogs comprising offspring from unaffected parents, and offspring from one and two affected parents, respectively, were used for the estimation of heritability according to published methods described for threshold characters [14].

That means, both parents of an affected dog must have at least one copy of the mutation and both parents must have passed a copy of the mutation to the offspring.

The scale of liability (standard deviation from threshold) within the population of dogs comprising offspring from unaffected parents and offspring from one and two affected parents respectively were used for the estimation of heritability according to methods described for threshold characters [12].

First - step relatives of affected dogs (parents, full and half siblings, and offspring) should be bred only to mates with pedigrees as clear of lymphoma as possible and who have no affected close relatives.

Recessive = two copies of a gene must be present before a dog is affected by the disease or trait, thus a carrier would have one copy of the gene to pass on to offspring but would not actually have the disease or trait.

When clinically normal dogs produce affected offspring, it strongly suggests the disease is inherited as a simple recessive (or potentially a polygenic — multiple gene) trait, and both parents carry one «bad» copy of the gene causing the disease.

Only 3 of the affected dogs had an affected parent, and breedings between an affected and an unaffected parent could produce either all unaffected offspring or a mix of affected and unaffected offspring in the same litter.

It is important to never breed two dogs together that carry one or more copies of the mutation, in order to avoid producing offspring that are affected with BFJE.

Test breeding of epileptic dams and sires done by veterinary researchers have produced incidences of epilepsy in the offspring ranging from between 38 % (affected to nonaffected) to 100 % (breeding together of two affected dogs).

The parents, full siblings, and offspring of CEA affected dogs or identified carriers should be tested if they are to be used for breeding.

For cataracts not due to HSF4, owners of the affected dog's parents and siblings and offspring should be notified.

The removal of affected dogs from the breeding pool has long been and remains an important form of prevention; the affected dog necessarily has genes for whatever disease it has and will pass them to its offspring.

Valuable dogs carrying unwanted genes which formerly might have been removed from breeding programs could be bred because breeders could determine the genotypes of prospective mates and eliminate the possibility of producing affected offspring.

In the case of recessive mutations, affected dogs — those with two copies of the mutation — should not be bred if there are serious quality - of - life or financial issues because all offspring will have at least one copy of the mutation.

If a dog is determined to be a carrier of CEA, either through testing or because it has affected offspring, it should be bred but only to a mates that have been tested clear of the mutation.

This means that, although the condition can be ameliorated in most cases with the proper treatment, the affected dog will always remain a carrier of the disease for the rest of its life and it can transmit the condition to its offspring.

A dog or bitch that has produced offspring with an inheritable disease, or that has a sire or dam affected by an inheritable disease is considered a carrier of that condition.

Dogs without any copies of the diseased gene or carriers with one copy of the PDP1 deficiency form of the gene will be clinically normal but the carrier will pass the affected gene to approximately half the offspring.

Retire from breeding any sire or dam who is affected with or has produced offspring with a known hereditary health defect unless said dog is used for the express purpose of testbreeding.

It should be noted that a unilaterally deaf dog can be as great a genetic risk for transmission of deafness to its offspring as is a bilaterally deaf dog, so BAER testing of puppies from affected breeds is important.

Clear dogs have two copies of the dominant gene and they are incapable of producing an offspring that is affected.

A dog that is homozygous affected (meaning he has two copies of the mutation) will always produce affected offspring.