Sentences with word «olanzapine»

In their study, Wright and PhD student Laura Castellani exercised mice by having them run until they reached exhaustion before giving them a dose of olanzapine.
McGlashan's clinical trial with olanzapine to prevent psychosis remains the only one yet to investigate antipsychotics as the sole intervention.
What is the efficacy and safety of variable dose olanzapine in people with borderline personality disorder?
Patients generally take such drugs as olanzapine over a long period, meaning that they may have serious impacts on patients» overall health, added Wright.
Just as McFarlane's preventive program was getting under way, Thomas McGlashan, a psychiatrist from Yale School of Medicine, was facing fierce opposition to his plan to try out the antipsychotic olanzapine as a preventive treatment.
Patients on olanzapine experienced more weight gain.
Switching to aripiprazole from olanzapine leads to weight loss in overweight people with schizophrenia or schizoaffective disorder
Published in the journal Scientific Reports, the study investigated how a single bout of intense exercise could reduce olanzapine - induced hyperglycemia in male mice.
Antipsychotics, particularly drugs like olanzapine (marketed as Zyprexa), have severe metabolic side effects, which include weight gain and other changes that heighten the risk of diabetes.
One need only review a few cases to start to see the problem with the three part test — for example, ramipril action, latanoprost NOC, olanzapine action # 2.
No significant difference between olanzapine and placebo for improvement in borderline personality disorder symptoms
Patients receiving quetiapine had modestly higher incidence rates of hyperglycemia and the metabolic syndrome and patients receiving olanzapine experienced the highest incidence rates (eTable 3).
Participants taking olanzapine started on 2.5 mg or 5 mg / day based on the investigator's judgement.
Two RCTs reported cannabis use outcomes following pharmacological interventions: one in people with major depression, alcohol dependence and cannabis abuse diagnoses (n = 22; fluoxetine vs placebo) and one in people with schizophrenia and cannabis and / or cocaine use disorders (n = 28; olanzapine vs risperidone).
Hayes noted a 2008 study that found lithium was nearly $ 500 cheaper per month compared with olanzapine.
Now a new University of Guelph study has revealed that a single bout of intense exercise performed right before taking a dose of olanzapine could be a way to prevent these side effects.
His new doctor tried a new medication: the antipsychotic olanzapine, which is thought to temper symptoms by blocking the brain's dopamine receptors and also acting on serotonin receptors.
There are also dopamine antagonists (such as Olanzapine or «Zyprexa») which blocks dopamine receptors.
In the early 1990s, Eli Lilly applied for patent protection in Canada for two chemical compounds, olanzapine and atomoxetine.
Clozapine, as well as other atypical antipsychotics are available, including risperidone, aripiprazole, olanzapine, quetiapine, and ziprasidone.
Olanzapine is an anti-psychotic medication that is used in the treatment of schizophrenia and causes blood sugar levels to rise with each dose taken.
Olanzapine (Zyprexa) and clozapine (Clozaril) are the top two offenders; studies have shown that on average these drugs cause patients to gain more than eight pounds in just 10 weeks.
Such atypical antipsychotic medications as Clozaril (clozapine), Risperdal (risperidone) and Zyprexa (olanzapine), most of which were introduced in the 1990s, appear to ameliorate schizophrenia symptoms by affecting the function of neurotransmitters such as dopamine and serotonin, which relay chemical messages between neurons.
Typical and atypical APMs were evaluated as two separate classes, as well as the most frequently used individual medications: aripiprazole, olanzapine, quetiapine, risperidone and ziprasidone.
The study of 6,671 individuals found lower rates of self - harm and unintentional injuries among those patients taking lithium compared with those prescribed valproate, olanzapine or quetiapine.
Joseph F. Hayes, M.Sc., M.B.Ch.B., of University College London, England, and coauthors compared rates of self - harm, unintentional injury and suicide deaths in patients prescribed lithium, valproate sodium, olanzapine or quetiapine using a large database of electronic health records in the United Kingdom.
Researchers linked the appetite - increasing effects of three such drugs — the so - called atypical antipsychotics clozapine (Clozaril), olanzapine (Zyprexa), and risperidone (Risperdal)-- to their capacity to neutralize the protein histamine, just as the antihistamine drugs that are used to treat allergies do.
The study focused on the most often used drugs in both classes: aripiprazole (Abilify), olanzapine (Zyprexa), quetiapine (Seroquel), risperidone (Risperdal) and ziprasidone (Geodon).
Patients taking lithium had lower rates of self - harm and unintentional injury compared to those taking other bipolar drugs, such as valproate (Depacon, Depakote), olanzapine (Zyprexa) or quetiapine (Seroquel), said lead researcher Joseph Hayes.
To compare lithium against newer medications, Hayes and his colleagues collected medical data on nearly 6,700 people diagnosed as bipolar and prescribed only one of the drugs — lithium, valproate, olanzapine or quetiapine.
These medication trials for the male patient: methylphenidate, amphetamine salts, dextroamphetamine, bupropion, sertraline, paroxetine, buspirone, lamotrigine, lorazepam, clonazepam, gabapentin, haloperidol, perphenazine, aripiprazole, olanzapine, quetiapine, and clozapine.
The common atypical antipsychotics include aripiprazole, asenapine, clozapine, lurasidone, iloperidone, olanzapine, risperidone and quetiapine.
Patents for drugs such as Eli Lilly's Zyprexa (olanzapine) or Pfizer's Xalatan (latanoprost) were invalidated in Canada for failing to uphold their end of the patent bargain despite their subsequent commercial success.
In addition to the drug rofecoxib, pharmaceutical companies have reportedly used ghostwriting to market sertraline, olanzapine, gabapentin, estrogen replacement therapy, paroxetine, methylphenidate, milnaciprin, venlafaxine and dexfenfluramine.
As we reported, the Federal Court considered the established parameters to calculate Teva's damages for being delayed from entering the olanzapine market, clarified evidentiary issues on fact witnesses and hearsay, and rejected Teva's argument that its damages should include a pipefill adjustment.
Teva sought damages from Eli Lilly Canada Inc. pursuant to section 8 of the Regulations, as compensation for having been prevented from coming to market in 2006 - 2007 with a generic version of ZYPREXA ® (olanzapine).
In particular, Eli Lilly claimed that the development of the «promise doctrine» in Canadian patent law led to the invalidation of patents protecting its drugs atomoxetine (Strattera ®) and olanzapine (Zyprexa ®) by Canadian courts, and that this doctrine was radically new, arbitrary, and discriminatory against pharmaceutical companies.
Acted for AAH Pharmaceuticals and Lloyds Pharmacy in patent litigation brought against them by Eli Lilly in relation to alleged infringement of the Olanzapine patent
The olanzapine patent is a selection; the atomoxetine patent was directed at improved side effects after long term dosing.
For example, Lilly's Notice ignores the fact that its olanzapine patent was a selection (from a known general class of compounds), and that Lilly had specifically stated in its patent (to back up its selection) that olanzapine has «marked superiority and a better side effects profile than prior known antipsychotic agents, and... a highly advantageous activity level.
Eli Lilly's selection patent for an antipsychotic agent (olanzapine) was first held invalid in 2007 (in preliminary type proceedings)(2007 FC 596).
PTSD is commonly treated using a combination of psychotherapy (cognitive - behavioral therapy, group therapy, and exposure therapy are popular) and psychotropic drug therapy (antidepressant or atypical antipsychotics, e.g. brand names such as Prozac (fluoxetine), Effexor (venlafaxin), Zoloft (sertraline), Remeron (mirtazapine), Zyprexa (olanzapine), or Seroquel (quetiapine)-RRB-.
Our data support recent findings that higher doses of olanzapine (> 10 mg / d) are associated with greater metabolic abnormalities.12 While data for risperidone were inconclusive, 12 our data suggest a dose - response relationship at doses higher than 1.5 mg / d.
Review: risperidone, olanzapine and haloperidol are the most effective drugs for acute mania in adults with bipolar I disorder
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