The effects of blood on ageing were first discovered in experiments that stitched young and
old mice together so that they shared circulating blood.
Vampire stories aside, the idea of rejuvenating the body with young blood dates back to macabre 1950s experiments that stitched young and
old mice together so they shared a circulatory system.
Not exact matches
Irina Conboy, a neurologist at the University of California, Berkeley, and her colleagues have performed extensive parabiosis experiments stitching
together young and
old mice that have been genetically matched.
Wagers, Lee, and their colleagues used parabiosis to yoke
together five 2 - year -
old mice (downright ancient in
mouse years) with 2 - month -
old counterparts.
They used a somewhat bizarre technique in which two
mice were sutured
together in such as way that they shared a circulatory system (known as parabiosis), and found
old mice joined to their youthful counterparts showed changes in gene activity in a brain region called the hippocampus as well as increased neural connections and enhanced «synaptic plasticity» — a mechanism believed to underlie learning and memory in which the strength of neural connections change in response to experience.
«It just reeks of snake oil,» said Michael Conboy, a cell and molecular biologist at the University of California, Berkeley, who's collaborated on studies sewing
old and young
mice together and transfusing blood between them.