Sentences with phrase «old mouse developed»

GREEN GLOB - LINS Spurred by a dose of misfolded proteins, a 20 - week - old mouse developed clumps of deformed proteins (green) in a cluster of cells called an islet (red) in its pancreas.

In 2010, Esmon and his colleagues compared how young and old mice developed clots in response to an infection.

Not exact matches

The team found neonatal mice with the mutations had normal - appearing skin, and the dry itchy skin of dermatitis did not develop until the mice were a few months old, the equivalent of a young adult in human years.

The researchers studied mice engineered to develop plaques in their brains when the animals are about 10 weeks old.

The brains of mice engineered to develop Alzheimer's disease were riddled with these plaques, clumps of amyloid - beta protein fragments, by the time the animals were 10 months old.

As a final step, the researchers fed the CTB - MBP - containing capsules to 15 - month - old mice, the equivalent of 80 or more human years, bred to develop Alzheimer's disease.

Additionally, the researchers report online today in Cell, old mice injected with this protein for 30 days developed younger, stronger heart tissue.

The researchers extracted mammary buds, the early developing form of the mammary gland, from 14 - day - old mouse embryos, which is a critical time for mammary development in rodents, according to Speroni.

Older mice became ill, but did not always develop infection, and they ultimately recovered.

When the scientists blocked Treg cells from accumulating in the fat by targeting a molecule that the immune cells require, mice no longer developed type 4 diabetes in old age.

Tilly and his team examined the ovaries of old mice in which the Bax gene had been «knocked out» in early embryos before they developed.

Older mice seem to benefit from such an arrangement, developing healthier organs and becoming protected from age - related disease.

The scientists infected 1 - day - old C57BL / 6 mice with Zika virus and found that they develop symptoms of neurological disease, such as unsteady gait and seizures that gradually fade over two weeks.

So the team engineered a mouse model that gradually lost the enzyme as it grew older and then bred those mice with rodents that were engineered to develop amyloid plaques from an age of 75 days.

Lloyd Old, Thierry Boon, and colleagues develop the TNF release assay for mouse systems in which release of TNF by T cells could be used to assess specific T cell recognition, facilitating the cloning of human tumor antigens.

Tanzi and Moir worked with youthful, four - week - old mice, which were a long way from developing amyloid - beta plaques.

Even though the mice were genetically predisposed to develop glaucoma — one of the leading causes of blindness in humans — they never did, no matter how old they got.

We observed no significant effect of genotype for any of these genes (data not shown), indicating that 7 - to 8 - month - old Grn − / − mice have not yet developed the elevated levels of inflammatory cytokines found at older ages (Filiano et al., 2013).

(A) The expression patterns of germ cell marker genes in monkey testis (5 years old), mouse embryonic fibroblast (MEF), monkey ES cells (ES), and developing EBs (days 3, 7, 14, 21, and 28) were examined using an RT - PCR analysis.

Four weeks - old patDp / + mice develop a low bone mass phenotype in the appendicular but not the axial skeleton compared to the littermate controls.