Sentences with phrase «old normal mice»

Nunez, Kim, Sakamoto and their colleagues carried out a careful series of experiments using both newborn and adult germ - free mice, and samples of gut microbes taken from the feces of 4 - day - old, 12 - day - old and 16 - day - old normal mice.

Left: The gut of a mouse that received a transplant of microbes from the gut of four - day - old normal mice, and then was exposed to Salmonella, while the other received a transplant of the four - day - old mouse microbes along with added Clostridia bacteria, before being exposed to Salmonella.

But when the researchers added bacteria from 16 - day - old normal mice, the amount of C. rodentium in the guts of surviving mice went down.

Raised in a germ - free environment, and then given a transplant of gut microbes from a four - day - old normal mouse, these mouse were still able to resist Salmonella infection without any help from their immune system — but only when they had received a dose of added Clostridium first.

They found that the samples from the older normal mice had the most diversity of their gut microbes, including Clostridia and Bacteroides bacteria not seen in the younger mice that were still getting their nutrition entirely from mother's milk.

Not exact matches

The team found neonatal mice with the mutations had normal - appearing skin, and the dry itchy skin of dermatitis did not develop until the mice were a few months old, the equivalent of a young adult in human years.

These mice performed better than their normal counterparts on learning tests well into old age, and their brains did not exhibit the decline in neurogenesis typically seen in aged mice.

Three groups of middle - aged mice (about a year old) were studied: one group ate a normal diet, in which fewer than 30 percent of calories came from fat, while two others were fed high - calorie diets in which 60 percent of the calories came from fat.

Older modified male mice metabolised sugar faster than normal mice and females, suggesting that SIRT6 might extend life by protecting against metabolic disorders such as diabetes.

«The mice also did not seem to gain weight when they got older, like normal mice do.

Normal mice reach sexual maturity at about 30 days old, but the leptin - treated mice blossomed about 3 days earlier, Flier says.

However, when the researchers knocked out SIRT1 in endothelial cells of 10 - month - old mice, then put them on a four - week treadmill running program, they found that the exercise did not produce the same gains seen in normal 10 - month - old mice on the same training plan.

They found that at 6 months of age, these mice had reduced capillary density and could run only half as far as normal 6 - month - old mice.

If an old mouse was p16 - deficient, it regrew pancreatic cells and cured itself like a normal young mouse.

The older mice fed a diet containing extra amounts of vitamin E, the equivalent to about 200 IU / day consumed by humans — about 10 times the Recommended Daily Allowance but well below the upper limit — were far more resistant to the bacteria than the older mice that had a normal amount of vitamin E in their diet.

However, by the time these mice reached adulthood, around 8 months old, the level of photoreceptor cells in these knockout mice was less than half the normal level.

Mice that had been eating a ketogenic diet performed at least as well on memory tests at old age as they did at middle age, while mice eating the normal diet showed an expected age - associated declMice that had been eating a ketogenic diet performed at least as well on memory tests at old age as they did at middle age, while mice eating the normal diet showed an expected age - associated declmice eating the normal diet showed an expected age - associated decline.

Based upon activity in multiple CNS toxicity assays, we identified an exceptionally potent, orally active, neurotrophic molecule called J147 that facilitates memory in normal rodents, and prevents the loss of synaptic proteins and cognitive decline when administered to three - month - old APP / swePS1ΔE9 mice for seven months [7].