Sentences with phrase «older mice cause»

Imbalances in the composition of gut microbes in older mice cause the intestines to become leaky, allowing the release of bacterial products that trigger inflammation and impair immune function.

Not exact matches

The researchers then infected younger and older mice with the bacteria Streptococcus pneumoniae, which causes so - called pneumococcal pneumonia.

This is because older mice lose the capacity to excrete adequate levels of two hormones: one that stimulates egg follicles to grow and mature and another that causes the ripened egg to be released from the ovary into the reproductive tract.

But in half the cells taken from old mice, microtubules sent chromosomes in different directions, causing clumps in three or four spots.

When the researchers measured the amount of virus present in different tissues, they found that, in addition to more virus in their blood and spleens, the older mice had 20-fold higher virus levels in their brains — which likely causes the excess deaths.

Extra vitamin E protected older mice from a bacterial infection that commonly causes pneumonia.

The research team studied older, male mice before and after they were infected with the pneumonia - causing bacteria.

Comparing 13 month old mice to 3 month old mice, blocking the femoral artery in the hind leg causes all older mice to lose their legs while only about a third of younger mice have to lose their legs.

I allowed the transgenic mice to lead me in many different directions, which caused problems as a new assistant professor trying to find a fundable niche, but it gave me a breadth of experience that I have tapped into as an older researcher.

Using a technique called parabiosis, in which the vascular systems of two mice are surgically connected, Villeda's lab had previously discovered that infusing old mice with the blood of younger mice leads to brain rejuvenation, including improvements in learning and memory, while infusions of old blood cause premature brain aging in young mice.

Even though the mice were genetically predisposed to develop glaucoma — one of the leading causes of blindness in humans — they never did, no matter how old they got.

However, removing huntingtin in mice older than 4 months appeared to cause no neurological problems, a stark contrast to the Dragatsis lab's work.

Muscle contraction tests caused the branched fibers to rupture, or tear apart, in the older mice.

Gene therapy in old mice has been shown to cause to a 27 % increase in strength, along with regeneration of aging muscle.