In rats,
olfactory bulb neurons use simple «linear summation'to make sense of fluctuating odor inputs from the surrounding environment...
Not exact matches
The
neurons send their signals to the brain's
olfactory bulb, where each of thousands of little clusters of
neurons called glomeruli receives input from
olfactory neurons with just one receptor type.
The brain (specifically, the
olfactory bulb and
olfactory cortex) then looks at the combination of sensory
neurons activated at any given time and interprets that pattern in the context of previous patterns that have been experienced and other kinds of available information.
A unique form of carbon dating, made possible by the Cold War, suggests that new
neurons rarely survive in the human
olfactory bulb after birth
The virus appears to invade the brain by infecting a type of glial cell called
olfactory ensheathing cells (OECs), which nourish smell - sensing
neurons and guide them from the
olfactory bulb to their targets in the nervous system.
Neurons in the mouse
olfactory bulb fire in a relatively narrow range, up to a few hundred times per second.
The team was able to view the responses of tens of
neurons at a time to signals arriving in the
olfactory bulb from the mouse's odor detectors, called
olfactory sensory
neurons, located in the nose.
Published in
Neuron, scientists at Cold Spring Harbor Laboratory (CSHL) report their discovery of a neural circuit in the mouse
olfactory bulb that explains how our mammalian cousins (and by extension, we) are able to adjust the gain on intense odors.
The scientists focused on the production of new
neurons in adult mice, in particular those
neurons that integrate into the
olfactory bulb, the brain region responsible for analyzing odors.
Normal mice with p16 had fewer neural stem cells in one part of the brain and fewer new
neurons in the
olfactory bulb, again demonstrating p16's ability to inhibit regeneration.
They then tracked
neurons as they migrated from region to region of the brain and found that new
neurons oriented in the direction of fluid flow rather than the direction of their ultimate destination in the
olfactory bulb.
Whereas 65 percent of new
neurons in wild mice ended up in the
olfactory bulb, little more than 9 percent of the mutants»
neurons were able to complete the journey.
Guidepost
neurons for the lateral
olfactory tract: Expression of metabotropic glutamate receptor 1 and innervation by glutamatergic
olfactory bulb axons.