We show that Olig2 +
oligodendrocyte precursor - like glioma cells invade by single - cell vessel co-option and preserve the blood - brain barrier (BBB).
Regulation of store - operated and voltage - operated Ca2 + channels in the proliferation and death of
oligodendrocyte precursor cells by golli proteins.
Modulation of Canonical Transient Receptor Potential Channel 1 in the Proliferation of
Oligodendrocyte Precursor Cells by the Golli Products of the Myelin Basic Protein Gene.
Regulation of L - type Ca + + currents and process morphology in white matter
oligodendrocyte precursor cells by golli - myelin proteins.
Previous research in rodent disease models has shown that transplanted
oligodendrocyte precursor cells derived from embryonic stem cells and from human fetal brain tissue can successfully create myelin sheaths around nerve cells, sometimes leading to dramatic improvements in symptoms.
Researchers at the Stanford University School of Medicine have succeeded in transforming skin cells directly into
oligodendrocyte precursor cells, the cells that wrap nerve cells in the insulating myelin sheaths that help nerve signals propagate.
Using tumor models for both astrocytoma and oligodendroglioma, which are very similar to human tumors, they could show that one and the same cell type, called
oligodendrocyte precursor cells, could give rise to both tumor forms.
Not exact matches
The study introduced here focused on a population of support cells in the spinal cord that helps to protect surviving nerve cells (neurons) after injury:
oligodendrocytes and their
precursor cells.
In his laboratory mice, Dr. Ding has now used chemical reprogramming to turn fibroblasts into neural «
precursor» cells with the potential to become new
oligodendrocytes.
One of the striking differences in outcome between our studies and work on
oligodendrocyte and
oligodendrocyte -
precursor replacement lies in the finding that differentiation of
precursor cells into a specific astrocyte subtype prior to transplantation provides a much greater level of benefit than transplantation of the
precursor cells themselves.