Unfortunately, myelin can be easily damaged by a variety of pathological conditions, and stresses to the brain, and
oligodendrocyte vulnerability to such damage is enhanced in the aged brain and in degenerative diseases.
Not exact matches
My laboratory studies the molecular mechanisms underlying the enhanced
vulnerability of
oligodendrocytes in neurodegenerative diseases such as Alzheimer's, including the age - related impairment of
oligodendrocyte regeneration from glial progenitors.