Sentences with phrase «oligomerization of»

In these fusions, ultraviolet light exposure caused oligomerization of the Dronpa domains thereby occluding the enzyme active site and shutting off the enzyme.

JAIN, R., et al. «Oligomerization of green fluorescent protein in the secretory pathway of endocrine cells.»

We discovered that levuglandins can greatly accelerate the oligomerization of amyloid beta and that the oligomers so formed are neurotoxic.

They are assembled by oligomerization of triple - helical protomers and are covalently crosslinked, a key reinforcement that stabilizes networks.

Not exact matches

Oligomerization is different from other self - catalyzed reactions of the intervening sequence RNA in that it involves intermolecular rather than intramolecular recombination, producing RNA molecules that are substantially larger than the original.

The observation that RNA molecules can catalyze their own oligomerization has possible implications for the evolution of chromosomes and for the replicative cycle of plant viroids and virus - associated RNA's.

Sometimes, proteins must be in an «oligomeric» state to be functional, although «oligomerization» of certain proteins can also lead to diseases.

The balance of expression of mutant and wild - type ACVR1 protein is likely to affect ligand binding dynamics, receptor oligomerization, internalization, and / or activation of downstream signaling pathways, as well as receptor response to environmental triggers that are clinical features of the natural history of FOP.

Systematic comparison of the effects of alpha - synuclein mutations on its oligomerization and aggregation.

Mislocalization of Oligomerization - Incompetent RDS is Associated with Mislocalization of Cone Opsins and Cone Transducin.

A major lab project involves the study of prohormone convertase enzymology and potential dominant negative effects (effects of oligomerization, the role of the inhibitory tail domain, and cellular targeting).

Disruption of oligomerization induces nucleocytoplasmic shuttling of leukemia - associated rho Guanine - nucleotide exchange factor.

Paladino, Simona, et al. «Protein oligomerization modulates raft partitioning and apical sorting of GPI - anchored proteins.»

These structures prevent end - to - end interactions that lower the solubility of RiAFP and lead to oligomerization and aggregation.

In this case, Tao found that the protein has a distinctive loop that is essential for self - oligomerization and encapsidation of the viral genome into a double - helical hairpin structure.

Not only does their work demonstrate that scientists have a basic understanding of what determines oligomerization, it also shows that they can design proteins with tunable shape, size, and symmetry for a variety of biological applications.

Structural determinants of human proton - coupled folate transporter oligomerization: role of GXXXG motifs and identification of oligomeric interfaces at transmembrane domains 3 and 6