Sentences with phrase «on cell block»

I encouraged them to hone their facility with these concepts by applying them to situations they encountered on the cell block, the music they listened to, and the TV shows they watched.

(Some additional shout - outs to: Frederick Wiseman's extraordinary Ex Libris; Scott Cooper's Searchers - throwback Western Hostiles; Agnes Varda's late - act collaborative documentary Faces / Places; the last half of Brawl on Cell Block 99; the epic look at Parisian ACT UP activists B.P.M. (Beats Per Minute); the Canadian zombie flick Les Affames; The Florida Project and Molly's Game, both coming to a theater near you very soon); the sheer balls on Darren Aronofsky for making mother!

One, Brawl On Cell Block 99 (B), depicted Vince Vaughn kicking multiple peoples» heads to jelly in canvas prison shoes while spouting the flowery, Nic Pizzolatto-esque tough - guy dialogue of director S. Craig Zahler (Bone Tomahawk).

Neville is none too pleased to see his son making trouble and upsetting the hierarchy of power on the cell block, so he coerces Eric to attend group therapy sessions to curb and harness his anger.

Not exact matches

It's only been tested on mice so far, but the results are tremendously promising for an antibody Stanford researchers have been experimenting with that blocks the body from «eating» cancer cells.

The names of her cell block buddies are also doing time on our girls» names list: Nicky leaped 35 percent, Piper jumped 28 percent, Dayanara climbed 19 percent, Alex rose 16 percent, and Gloria is up 10 percent.

A 23 - year - old Orland Park man was charged with illegally using a cell phone while driving, improper lane use, cannabis possession and not having his driver's license with him during a Feb. 7 traffic stop on the 0 - 100 block of Orland Square Drive.

The fields within biology are further divided based on the scale at which organisms are studied and the methods used to study them: biochemistry examines the fundamental chemistry of life; molecular biology studies the complex interactions of systems of biological molecules; cellular biology examines the basic building block of all life, the cell; physiology examines the physical and chemical functions of the tissues and organ systems of an organism; and ecology examines how various organisms interrelate.

Chronic cigarette smoke exposure, as noted in many human cancers, tends to block these cell maturation genes from properly turning on, says Baylin.

Then the researchers doused dengue - spreading mosquitoes with a chemical that shuts down the mosquitoes» ability to detect CO2 by blocking a receptor called neuron — cpA, a type of sensory cell found on a small pair of antennalike structures near the mouth called the maxillary palps.

Instead, they enter their target less disruptively and move on to disrupt the DNA within or block cell division or trigger cellular self - destruction.

While the combination therapies block off the principal pathway that cancer cells use to fuel their growth, the cells come to bypass this blockade and, like vehicles on a detour route, make use of additional pathways to continue growing and spreading.

So far the blocks have been used to build a variety of living 3D shapes that have never before been created on a cell - by - cell basis, such as tubes and solid spheres.

Commenting on the study for ESMO, Dr Olivier Michielin, head of Personalised Analytical Oncology, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland, said: «Omaveloxolone's novel mechanism of action is to block MDSCs, cells known to suppress the immune response.

On to the blocks were poured a mixture of recombinant human bone morphogenic protein (BMP) powder — a genetically engineered protein that causes cells to ossify or become bone — and liquid bone marrow containing stem cells.

Cells are the basic building blocks of all life on our planet.

A study published on December 3rd in PLOS Pathogens suggests that one such strategy blocking the PD - 1 / PD - L1 pathway works, but only when the overall HIV load is low and regulatory T cells cooperate.

Based on these ex vivo experiments (in cells isolated from patients and then exposed to PD - L1 blocking agents outside of the body), they predict that when actual patients are given PD - L1 blocking agents, their viral load at the time will influence the «net» outcome, i.e., whether the blockage boosts or weakens the overall anti-HIV immune response.

This drug (vedolizumab) blocks a specific adhesion molecule on the surface of the T - cell and thereby inhibits immune cells from binding themselves to receptors present in the intestine, preventing the T - cells from penetrating the blood vessels in the intestinal tissue.

There is currently a PD - 1 antibody on the market that blocks T cell exhaustion in patients with solid tumors, like lung cancer and melanoma.

Studying mice with injuries to the lining of the stomach, the researchers blocked the animals» ability to call on stem cells for help in the stomach.

The researchers observed the effect of the synthetically produced molecule, JK - 31, on the growth and proliferation of a model human breast cancer cell line and found that it effectively blocked the protein cyclin - dependent kinase 1 (CDK1), which plays a key part in the process of the division of cancer cells, and therefore inhibited the proliferation of the cells.

The drug blocks CTLA - 4, a protein receptor on the surface of T - cells that serves as a molecular stop sign, preventing the immune system from going into overdrive.

PARP inhibitors target and block proteins which cancer cells depend on to repair DNA for their survival.

The researchers demonstrated that blocking the PGD enzyme genetically or with a pharmacologic inhibitor reversed the epigenetic reprogramming and malignant gene expression changes detected in distant metastases, and also strongly inhibited their tumor - forming capacity, with no effect on normal cells or peritoneal pancreatic cancer controls.

Patients received a tandem of lenalidomide, a drug that kills tumor cells, blocks blood vessel growth, and acts on the immune system, and dexamethasone, an anti-inflammatory agent, plus one of three new agents:

► On Wednesday at ScienceInsider, Tania Rabesandratana reported from Brussels that the European Commission has denied a request by a citizens» initiative to «block E.U. funding for research using embryonic stem cells.»

An early - stage clinical study by another institution, published in the Lancet Oncology in May 2016, combined chemotherapy with an experimental drug that blocks CCR2, a receptor on monocytes and macrophages whose activation stimulates these cells to infiltrate tumors.

The finding, reported by a Stand Up to Cancer - Prostate Cancer Foundation Dream Team in the May 21 edition of the journal Cell, is based on an analysis of tumor samples from 150 men with metastatic prostate cancer that no longer responded to standard hormone - blocking therapy.

In treating acne, the focus — just as it was decades ago — is on three key factors: preventing dead skin cells from blocking the oil glands, reducing excessive oil production and reducing acne - causing bacteria.

Maged Harraz, Ph.D., a research associate and the first author of the newly published research paper, says the researchers already knew that ketamine interacts with excitatory NMDA receptors on nerve cells in the brain to block their activity.

The patients received biweekly infusions of nivolumab, which is an antibody that blocks a protein called PD - 1 on the surface of immune system T cells.

This blood vessel normalization results in an increased barrier function on the one hand — thereby blocking cancer cell dissemination and metastasis - and in enhanced tumor perfusion on the other hand, which increases the response of the tumor to chemotherapy.

The drug's mechanism of action was entirely new: Instead of attacking cancer cells (like chemo), or indiscriminately revving up the immune system (like IL - 2), ipilimumab blocked a single receptor on one type of immune cell.

I definitely had a few things to learn, and, being the newest kid on the departmental block, I got tapped on the shoulder to be the representative from Cell Biology and Anatomy on the Graduate Council, which oversees graduate studies at OHSU.

In their newly published study, the researchers aimed to investigate the effect of blocking autophagy on the infiltration of NK cells in melanoma.

A long - shot attempt to block U.K. researchers from creating human - animal hybrid cells or embryos has ended quickly, with a judge dismissing a new lawsuit filed by the Christian Legal Centre and the Comment on Reproductive Ethics and ruling that the groups should pay # 20,000 in court costs.

In the latter group, a neutralizing antibody blocked TNF and prevented it from binding to a receptor on the premalignant liver cells; loss of the receptor prevented the TNF from triggering a molecular cascade that turns on the NF - kB master switch.

The antibody blocks CTLA - 4, a protein switch on the surface of T cells that, when turned on, dampens their activation.

On the other hand, when the researchers blocked f - circRNA activity, the cells» normal behaviors were restored.

As Louis H. Miller, Head of Malaria Cell Biology Section at the National Institutes of Health notes, «The findings on the liver receptor EphA2 for malaria parasite sporozoite invasion of liver cells is a critically important advance and might allow us to devise new strategies to block parasite infection.»

Allison pioneered immune checkpoint blockade, an approach that treats the immune system, rather than the tumor directly, by blocking molecules on T cells that shut those attack cells down, protecting tumors from immune response.

Building on previous work from Yuan's lab showing that the activity of RIPK1 could be blocked by a chemical called necrostatin - 1, the research team tested how ALS cells in lab dishes would respond to the same treatment.

«While working on this project with cell biologists at the Hebrew University of Jerusalem, we have been able to verify various hypotheses by selectively replacing specific metabolic products whose synthesis had been blocked by the toxic substance,» Duschl explains.

That's according to researchers from The University of Manchester who have discovered that the virus protein uses its flexible arms to pass on viral building blocks to the proteins of cells that it hijacks.

The discovery could pave the way for new treatments that are able to block cell signals switched on in tumours with low levels of PTEN.

Patients in the study were treated with immune checkpoint inhibitors that block the activation of PD1, a protein on immune system T cells that halts immune response.

The research team learned the virus brings with it to the cell a protein called UL138 that blocks the cellular lysine demethylases from turning the virus back on.

To block this signal, recent clinical studies have focused on inhibiting the activation of the B - cell receptor as a treatment for non-Hodgkin lymphoma patients, but with variable success.

In gymnosperms, wind deposits a pollen grain on an exposed egg cell, and then the pollen tube — growing at the slow rate of 20 micrometers an hour — releases an enzyme that destroys any tissue blocking the sperm's entrance into the egg cell.