Sentences with phrase «on epigenomics»

Not exact matches

DURECT Corp. is a biopharmaceutical company focused on two areas of active drug development: New therapeutics based on its proprietary drug delivery platforms and new chemical entities derived from its epigenomic regulator program.

Currently, enhancers can be identified through chromatin - based assays, such as ChIP - seq, which predict enhancer elements indirectly based on the enhancer's association with specific epigenomic marks, such as transcription factors or molecular tags on DNA - associated histone proteins.

«This is exactly the technology you could use to look for epigenomic changes in specific cell types,» says Martienssen, who is also on the International Human Epigenome Consortium's steering committee.

In a new study published in the journal, Epigenomics, the researchers focused on whether a post-weaning diet, or a diet later in life, could control the epigenome and affect metabolism in the body.

Dr Simone Ottonello, from the University of Parma, Italy says: «If extended to black truffles from different geographic areas, epigenomic analyses, such as the one described in this work, may shed light on the relationships between DNA methylation and transposon - mediated genome shaping, intraspecific variability and commercially relevant organoleptic traits such as aroma and color»

But Epigenomics plans to set up a proprietary database on differences between healthy and diseased tissues to flag, for example, patterns associated with tumors.

Masafumi now leads his own group at the University of Tsukuba in Japan, with a focus on genomics and epigenomics of clinical samples.

Genetic data combined with information on gene expression and epigenomics in relevant tissues, and clinical information, can provide clues about the effects of genetic changes within an individual's genome that increase or decrease one's risk of developing type 2 diabetes and its complications, including heart and kidney disease.

Epigenomics studies the chemical tags that lie just outside our genes and direct whether particular genes switch on or off.

Researchers are building a database of DNA sequence, functional and epigenomic information, and clinical data from studies on type 2 diabetes and its macro - and microvascular complications, and creating analytic tools to analyze these data.

«The McMurdo Dry Valleys in Antarctica are the closest terrestrial analog we have to what's happening on other planets,» says David Goerlitz, director of operations for the Genomics and Epigenomics Shared Resource at Georgetown University Medical Center.

Once finished, however, an epigenomic map could also prove useful in determining which individuals are at risk for certain diseases and encouraging the kind of lifestyle changes that can prevent the wrong genes from switching on or off.

In particular, this meeting will focus on addressing the technological challenges and opportunities presented by the Human Cell Atlas in areas including large - scale single - cell RNA sequencing, spatially - resolved methods, single - cell proteomics, epigenomics, and sample handling.

His primary research interests are bioinformatics, computational biology, machine learning, and integrative analysis of high throughput sequencing data with an emphasis on regulatory genomics and epigenomics.

She is Chair of the Scientific and Medical Advisory Board and serves on the Board of Trustees of The United Mitochondrial Disease Foundation (UMDF); founding member of the CHOP Center for Mitochondrial and Epigenomic Medicine (CMEM); CHOP - site PI of the North American Mitochondrial Disease Consortium (NAMDC); member of the Mitochondrial Medicine Society (MMS), Society for Pediatric Research (SPR), Society for Inherited Metabolic Disease (SIMD), American Society of Human Genetics (ASHG), and American College of Medical Genetics and Genomics (ACMGG); and elected member of the University of Pennsylvania John Morgan Society (JMS), Interurban Clinical Club (ICC), and American Society of Clinical Investigators (ASCI).

In particular, this meeting focused on addressing the technological challenges and opportunities presented by the Human Cell Atlas in areas including large - scale single - cell RNA sequencing, spatially - resolved methods, single - cell proteomics, epigenomics, and sample handling.

Finally, the explosion of the «omics (microbiomics, genomics and epigenomics, etc.) and their roles in precision medicine will hopefully be areas of focus that I can bring to bear on the health of patients through the internal environment, or «milieu».

Lausanne, Switzerland About Blog Epigenomics and Epigenetics queries the developmental origins of health and disease by cataloguing the sets of physical markings on chromatin that collaborate to stably alter gene expression.