Sentences with phrase «on human gut microbiota»

Influence of fecal collection conditions and 16S rRNA gene sequencing at two centers on human gut microbiota analysis — Jocelyn Sietsma Penington — Scientific Reports

Not exact matches

Using a «gnotobiotic mouse model» — where mice were «colonized with a synthetic human gut microbiota composed of fully sequenced commensal bacteria» — Desai et al reported on the effects of different diets with different fibre content.

Dr Luis Pedro Coelho, commented: «These findings suggest that dogs could be a better model for nutrition studies than pigs or mice and we could potentially use data from dogs to study the impact of diet on gut microbiota in humans, and humans could be a good model to study the nutrition of dogs.

The Wyss team believes the ability of the human gut - on - a-chip to culture the microbiome with human gut cells also holds promise for the field of precision medicine, where a patient's own cells and gut microbiota could one day be cultured inside a gut - on - a-chip for testing different therapies and identifying an individualized treatment strategy.

«Healthy gut bacterial communities are known to benefit immune regulation, metabolism and potentially even the nervous system, so if cholera or other diarrheal diseases permanently impact the microbiota, there could be long - term effects on human health,» explains Regina LaRocque, MD, MPH, of the Massachusetts General Hospital (MGH) Division of Infectious Diseases, co-senior author of the paper.

Given that the investigators have previously shown the influence of the host molecular clock on the gut microbiota, they will also ask if taking this NSAID at different times of day might lead to higher efficacy and less side effects in animal models and eventually in humans.

At Weizmann, she plans to investigate the impact of gut microbiota on aging, and her goal is to improve human health through personalized nutrition.

A few interesting articles in early life human microbiome, plus: A comparison between Staphylococcus epidermidis commensal and pathogenic lineages from the skin of healthy individuals living in North American and India; A new tool to reconstruct microbial genome - scale metabolic models (GSMMs) from their genome sequence; The seasonal changes in Amazon rainforest soil microbiome are associated with changes in the canopy; A specific class of chemicals secreted by birds modulates their feather microbiome; chronic stress alters gut microbiota and triggers a specific immune response in a mouse model of colitis; and evidence that the short chain fatty acids profile in the gut reflects the impact of dietary fibre on the microbiome using the PolyFermS continuous intestinal fermentation model.

The Gut Metagenome Changes in Parallel to Waist Circumference, Brain Iron Deposition and Cognitive Function JCEM June 7, 2017 Gerard Blasco, Jose Maria Moreno - Navarrete, Mireia Rivero, Vicente Perez - Brocal, Josep Garre - Olmo, Josep Puig, Pepus Daunis - i - Estadella, Carles Biarnes, Jordi Gich, Fernando Fernandez - Aranda, Angel Alberich - Bayarri, Andres Moya, Salvador Pedraza, Wifredo Ricart, Miguel Lopez, Manuel Portero - Otin, and Jose - Manuel Fernandez - Real Microbiota perturbations seem to exert modulatory effects on emotional behavior, stress - and pain - modulation systems in adult animals; however, limited information is available in humans...

Hence, a lot of necessary neurotransmitters in the body are generated by the gut microbiota, exerting influence on the human body including the brain, among which many neurotransmitters in the human gut microbiota are also critical molecules.»

Nutrition - derived bioactive metabolites produced by gut microbiota and their potential impact on human health

The delicate balance between the human microbiome and the development of psychopathologies is particularly interesting given the ease with which the microbiome can be altered by external factors, such as diet, 23 exposure to antimicrobials24, 25 or disrupted sleep patterns.26 For example, a link between antibiotic exposure and altered brain function is well evidenced by the psychiatric side - effects of antibiotics, which range from anxiety and panic to major depression, psychosis and delirium.1 A recent large population study reported that treatment with a single antibiotic course was associated with an increased risk for depression and anxiety, rising with multiple exposures.27 Bercik et al. 28 showed that oral administration of non-absorbable antimicrobials transiently altered the composition of the gut microbiota in adult mice and increased exploratory behaviour and hippocampal expression of brain - derived neurotrophic factor (BDNF), while intraperitoneal administration had no effect on behaviour.

Effects of a gluten - free diet on gut microbiota and immune function in healthy adult human subjects.

The closest I've found to a human clinical trial of beans on intestinal permeability is this study, which found a Chinese medicinal gruel of Job's tears, oat, buckwheat, white bean, yellow corn, red bean, soybean, yam, big jujube, peanut, lotus seed, and wolfberry changed gut microbiota, improved gut permeability, lowered endotoxemia, and improved inflammation markers.

Sources: Clemente, J.C., et al., «The Impact of the Gut Microbiota on Human Health: An Integrative View,» Cell 2012; 148 (6): 1258 - 1270.