Sentences with phrase «on islet cell»

«You can totally protect those mice from mortality, which is really extraordinary,» says Dr. Lipes, an Investigator in Joslin's Section on Islet Cell & Regenerative Biology and an Assistant Professor at Harvard Medical School.

Amy J. Wagers, Ph.D., is an investigator in the section on islet cell and regenerative biology at the Joslin Diabetes Center in Boston, Mass., and an associate professor of stem cell and regenerative biology at the Harvard Medical School..

Rohit N. Kulkarni, M.D., Ph.D., is Principal Investigator in the Section on Islet Cell & Regenerative Biology at Joslin Diabetes Center and an Associate Professor of Medicine at Harvard Medical School.

«I'm a big proponent of islet cell transplantation for type 2 diabetics,» says Dr. Gordon Weir, who is one of the world's foremost experts on islet cell transplantation as Co-Head...

If we could find therapies that detect complications at an early stage, people with diabetes could lead healthier, more productive lives,» says senior author Rohit Kulkarni, M.D., Ph.D., Principal Investigator in the Section on Islet Cell and Regenerative Biology at Joslin Diabetes Center and Associate Professor of Medicine at Harvard Medical School.

Rohit N. Kulkarni, M.D., Ph.D., Senior Investigator in the Section on Islet Cell and Regenerative Biology at Joslin Diabetes Center and Professor of Medicine at Harvard Medical School.

She is an Investigator in the Section on Islet Cell & Regenerative Biology at Joslin Diabetes Center and an Assistant Professor of Medicine at Harvard Medical School.

Research is already underway at City of Hope to unlock the immune system's role in diabetes, including T cell modulation and stem cell - based therapies that may reverse the autoimmune attack on islet cells in the pancreas, which is the cause of T1D.

Not exact matches

The JDF Center for Islet Cell Transplantation will fund 32 researchers to focus on four main goals: Reversing the overactive immune response that kills islet cells; finding new sources for islet cell transplants, such as pigs or genetically engineered cells; persuading the body to accept the transplanted cells without immunosuppressive drugs that often trigger worse side effects than the disease; and overcoming the technical difficulties of transplantaIslet Cell Transplantation will fund 32 researchers to focus on four main goals: Reversing the overactive immune response that kills islet cells; finding new sources for islet cell transplants, such as pigs or genetically engineered cells; persuading the body to accept the transplanted cells without immunosuppressive drugs that often trigger worse side effects than the disease; and overcoming the technical difficulties of transplantatCell Transplantation will fund 32 researchers to focus on four main goals: Reversing the overactive immune response that kills islet cells; finding new sources for islet cell transplants, such as pigs or genetically engineered cells; persuading the body to accept the transplanted cells without immunosuppressive drugs that often trigger worse side effects than the disease; and overcoming the technical difficulties of transplantaislet cells; finding new sources for islet cell transplants, such as pigs or genetically engineered cells; persuading the body to accept the transplanted cells without immunosuppressive drugs that often trigger worse side effects than the disease; and overcoming the technical difficulties of transplantaislet cell transplants, such as pigs or genetically engineered cells; persuading the body to accept the transplanted cells without immunosuppressive drugs that often trigger worse side effects than the disease; and overcoming the technical difficulties of transplantatcell transplants, such as pigs or genetically engineered cells; persuading the body to accept the transplanted cells without immunosuppressive drugs that often trigger worse side effects than the disease; and overcoming the technical difficulties of transplantation.

Kim and his colleagues are planning to continue their studies of pancreatic and islet - cell development as part of a Stanford focus on diabetes and metabolism research.

Depending on the concentration of cannabinoids and the activity of two different receptors, the islets became larger or smaller, while the alpha cells, usually located outside the islets, were able to migrate inside,» explains Dr. Katarzyna Malenczyk fom the Nencki Institute, the first author of the publication.

She says getting the correct dosage is all - important and plans to develop a biomarker to show whether the BCG is having even a subtherapeutic effect on the immune cells that target islets.

Seeking fresh sources, they looked for cells that express the gene neurogenin 3, a potential sign of cell differentiation because it is the first gene to only switch on in pancreatic islets during embryonic development.

Dr. Kulkarni's research focuses on investigating signaling pathways impacting growth and function of pancreatic islet cells with the long - term goal of improving therapeutic approaches for the treatment of type 1 and type 2 diabetes and obesity - associated conditions.

Our group is specifically working on improvement of islet isolation and transplantation protocols in clinical practice and the development of novel therapeutic options in the field of beta cell replacement with a clear translational «bench to bedside» approach by linking experimental research with preclinical and clinical work:

SAN DIEGO, September 9, 2016 — ViaCyte, Inc., a privately - held regenerative medicine company with the first pluripotent stem cell - derived islet replacement therapy for the treatment of diabetes in clinical - stage development, today announced participation on a panel at the 2016 BioPharm ™ America — 9th Annual International Partnering Conference.

San Diego, California, October 6, 2014 — ViaCyte, Inc., a privately - held regenerative medicine company developing a stem cell - derived islet replacement therapy for the treatment of diabetes, called VC - 01 ™, will give two presentations at the annual Stem Cell Meeting on the Mesa Conference, being held at the Estancia La Jolla Hotel & Spa and The Salk Institute for Biological Studies, as follcell - derived islet replacement therapy for the treatment of diabetes, called VC - 01 ™, will give two presentations at the annual Stem Cell Meeting on the Mesa Conference, being held at the Estancia La Jolla Hotel & Spa and The Salk Institute for Biological Studies, as follCell Meeting on the Mesa Conference, being held at the Estancia La Jolla Hotel & Spa and The Salk Institute for Biological Studies, as follows:

On the other hand, a Brs3 agonist promoted insulin secretion in both rodent insulinoma cell lines and in islets isolated from wild - type but not Brs3 mutants [53].

After implantation, these cells are expected to become mature human islet tissue including well - regulated beta cells producing insulin on demand.

Two studies find adult pancreatic cells maintain islet population, contradicting a hypothesis that regeneration relies on stem cells

Based on animal experimentation, PEC - 01 progenitor cells have the capacity to both self - renew; making more cells, and differentiate into mature, functional pancreatic islet cells.

* Oddly enough, however, the experiments with fresh pancreatic islets and fat cells taken from the mice suggested that the positive effects of uncarboxylated osteocalcin on insulin only occurred at concentrations extremely low compared to those of undercarboxylated osteocalcin normally present in mice, while the effects on adiponectin and energy expenditure only occurred at normal to high concentrations.

A novel investigative study published in the Nov 2014 issue of the Journal of Endocrinology looked at the effects of curcumin on insulin - producing cells within the pancreas called Beta cells (or B - cells) and Islet cells, in relation to imbalanced blood sugar.