We then assessed the consequences of Slc6a14 deletion
on PyMT - driven breast cancer in these mice.
Not exact matches
Additionally, they examine MMTV -
PyMT control or POSTN null mice to test the effect of POSTN
on primary tumor growth and metastasis (Figures 3A, 3B, and S13; Malanchi et al., 2012).
The first experiment is to measure metastatic lung cancer in MMTV -
PyMT transgenic mice crossed with the POSTN Knock out mice, and controls, with focus
on the role of periostin in metastatic progression.
However, when crossed with
PyMT - Tg mice or MMTV / Neu (mouse mammary tumour virus promoter - Neu)- Tg mice, the development and progression of breast cancer were markedly decreased
on Slc6a14 − / − background.
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