Sentences with phrase «on a breast cancer cell line»

Ana Soto, professor of cellular biology at Tufts University School of Medicine, and her colleagues were studying the effects of estrogen on a breast cancer cell line.

One study examined the cytotoxic effects of different types of clove extract on breast cancer cell lines, including water - based, alcohol - based and essential oil extracts.

Not exact matches

The researchers observed the effect of the synthetically produced molecule, JK - 31, on the growth and proliferation of a model human breast cancer cell line and found that it effectively blocked the protein cyclin - dependent kinase 1 (CDK1), which plays a key part in the process of the division of cancer cells, and therefore inhibited the proliferation of the cells.

If a breast cancer line had silently contaminated Klonisch's cell culture early on, it would have been subject to the usual technique for immortalizing a normal cell (which involves applying enzymes, antibiotics and antibiotic - resistant genes).

To see whether cancer stem cell renewal involves a chain of events similar to that used by embryonic stem cells, and whether the process was affected by oxygen levels, Semenza and graduate student Chuanzhao Zhang focused their studies on two human breast cancer cell lines that responded to low oxygen by ramping up production of the protein ALKBH5, which removes methyl groups from mRNAs.

Banik cautions that neither of the contrast agents has yet been tested on animals injected with breast cancer cell lines, which he calls an important step to take.

The researchers have isolated the sesquiterpene lactone damsin from the plant and studied its effect on cancer stem cells in three different breast cancer cell lines.

The resulting «map» of gene - drug interactions allowed the researchers to accurately predict the responses of multiple human cancer cell lines to different chemotherapy agents based on the cell lines» genetic profiles and also revealed new genetic factors that appear to determine the response of breast and ovarian tumor cells to common classes of chemotherapy treatment.

In a four - year study conducted on the mouse model in advanced breast cancer metastasis in the eye's anterior chamber, Petty and colleagues found that the new nanoparticle not only killed tumor cells in the eye, but also extended the survival of experimental mice bearing 4T1 tumors, a cell line that is extremely difficult to kill.

In the current study, the researchers tested AAV2 on a cell - line representative of triple - negative breast cancer.

To study the effect of hypoxia / reoxygenation cycles on breast cancer, we exposed two metastatic human breast cancer cell lines (MDA - MB 231 and BCM2) to cycles of chronic hypoxia and nutrient deprivation.

MUC1 is protein found on epithelial cells, such as those that line the intestine, that is overexpressed in many cancers, including colorectal and breast cancers.

The effect of a novel antagonist of growth hormone releasing hormone on cell proliferation and on the key cell signaling pathways in nine different breast cancer cell lines.

Both reviewers consider that since the functional studies were only tested in 2 basal and 2 luminal breast cancer cell lines, the sample set was too small, and testing additional cell lines for their dependency on MELK should further strengthen the authors conclusions.

Red foods like red bell peppers and tomatoes contain a phytochemical called lycopene, which may have an anti-inflammatory affect on the cells lining the heart and blood vessels, and may reduce the risk of developing prostate cancer among other cancers such as breast, lung, bladder, ovarian, and colon.

Those are cells that were taken from nun many years ago that had breast cancer and they propagated them and they do a lot of the research on this line of cells that actually came from a nun that had breast cancer called MCF - 7 estrogen dependent breast cancer.