Which parent a chromosome comes from is important because the activity of some genes varies depending on whether the genes are
on a chromosome inherited from the mother or from the father.
Not exact matches
A girl who
inherits one defective copy of such a gene from her parents has a backup
on her other X
chromosome.
The causative gene for Huntington's disease, HD, one of the first genes identified to cause an
inherited disease, is located
on chromosome 4.
The 1 - cell embryo (left) shows the mark (green)
inherited on sperm
chromosomes but not
on the oocyte
chromosomes (pink) from a mutant mother lacking the methylation enzyme PRC2.
Right: By altering both
chromosomes, gene drives ensure both copies of the altered gene are
inherited, leading to a 100 percent chance of passing it
on.
The gene is silenced because it is
on the part of their
chromosome they
inherited from their mother, and for mysterious reasons our cells use the father's copy of this gene.
Defective genes can be caused by mutations in either the maternally -
inherited mitochondrial genome (mtDNA) or more frequently, the genes located
on the autosomes, the 23 pairs of
chromosomes which are responsible for all traits and all other genetic diseases.
But then a gene
on a single
chromosome mutated in a way that made any individual that
inherited it male.
The finding fits with earlier studies that have found that although living Asians and Europeans have
inherited 1 % to 3 % of their DNA from their ancestors» interbreeding with Neandertals, they are missing chunks of Neandertal DNA
on their Y
chromosomes.
Genes which lie close to one another
on a
chromosome are usually
inherited together and are said to be linked.
Geneticists have so far concentrated
on genes that are linked to disease: first the simple but rare
inherited diseases like cystic fibrosis (the gene for which is
on chromosome 7) or Huntington's (
chromosome 4), then the environmental diseases for which different people
inherit different susceptibilities, such as Alzheimer's (
chromosome 19) or breast cancer (
chromosomes 13 and 17).
Furthermore, the team determined that Papuans have more Denisovan DNA
on their autosomes,
inherited equally often from both parents, than
on their X
chromosomes,
inherited twice as often from the mother.
Each
chromosome contains genes that are imprinted; that is, they are specifically turned off or
on depending
on whether they were
inherited from the mother or the father.
But the pattern is indicative of a trait passed down the maternal line
on the X
chromosome,
inherited from the mother.
In this case, Zhijian «Jake» Tu and colleagues found that placing a particular Y
chromosome gene
on the autosomes of Anopheles stephensi mosquitoes — a species responsible for transmitting malaria — killed off 100 percent of all female embryos that
inherited this gene.
Reconstructing relationships using genetic information
on the paternally
inherited Y
chromosome, the maternally
inherited mitochondria and the bi-parentally
inherited autosomes have suggested contradictory conclusions.
The authors exploited linkage disequilibrium (the tendency of variants
on the same
chromosome to be
inherited together) to identify, in Europeans, variants that tend to be
inherited together with associated SNPs.
The plant genes responsible for contributing these peptides in wheat gluten are located
on the third set of
chromosomes that the hexaploid variants
inherited from their wild parent.
Some other traits, like size, are complexly
inherited from many locations, including ones
on chromosomes 1, 3, 4, 7, 10, 15, and more.
These conditions are
inherited as X
chromosome linked disorders, meaning only male dogs can become affected with the disease, while female dogs, though not clinically affected, can carry the mutation and pass it
on to their young.
Segments of DNA that are located
on the same
chromosome are «linked» because they are likely to be
inherited together, with the segments in closest proximity being the most likely.
Normal male cats only
inherit one X
chromosome so this is active in all skin cells as there is nothing equivalent
on the Y
chromosome which could «switch off» the O gene.