Sentences with phrase «on a genetic level by»

Not exact matches

The upside, however, was that once I knew, I was able to convince a zoology professor to let me do my M.S. in his roundworm lab by comparing strains that looked alike under the microscope but weren't on a genetic level.

Now, researchers have found that these diseases have also left their mark on modern - day populations: A new study suggests that infectious diseases brought by Europeans, from smallpox to measles, have molded the immune systems of today's indigenous Americans, down to the genetic level.

In order to analyze the effect of seed dispersal by monkeys on a spatial genetic level, the scientists examined three different developmental stages of the trees.

«Our strategy to treat SMA relies on a simple, powerful antisense method that boosts SMN protein levels by fixing a genetic RNA splicing glitch.

The team's work highlights this by presenting a comprehensive view of genome evolution on many different levels (e.g., differences in ploidy, aneuploidy, genetic variants, hybridization, and introgressions) that is difficult to obtain at the same scale and accuracy for other eukaryotic organisms.

The EGA serves as archive for publication as well as data on several levels, including the raw data (so they could be re-analysed in the future using other algorithms) and the genotype calls (information about pathogenic genetic variants) provided by the data submitters.

The overall score encompass several factors: reproducibility of the antibody staining in different cell lines (and if signal strength correlates with RNA expression levels); assays for enhanced antibody validation by using antibodies binding to different epitopes on the same target protein (independent antibodies), by knockdown / knockout of the target protein (genetic methods) and by matching of the signal with a GFP - tagged protein (recombinant expression); experimental evidence for location described in literature.

Trees visited by the different moths show parallel divergence in multiple traits, and they are separate on a genetic level as well.

Genetic studies using samples along the distribution range of both subspecies and based on a few dozen nuclear markers have revealed loci of relatively high divergence (0.3 — 1.2 %) between subspecies embedded in a genome otherwise characterized by low levels of differentiation and high levels of bidirectional gene flow [21], [24]--[26], likely facilitated by high effective population sizes, high dispersal, and a relatively short generation time [21], [24]--[26].

ApoE as a major causative factor and therapeutic target in Alzheimer's disease and other neurodegenerative disorders; small - molecule structure correctors to convert apoE4 to apoE3 and reverse the detrimental effects of apoE4 on mitochondria and the cytoskeleton; small - molecule protease inhibitors to block the formation of toxic fragments of apoE4; Plasma lipoprotein metabolism regulation involving apoE and apoB; cholesterol homeostasis modulation by lipoprotein receptors controlling lipoprotein clearance by the liver; Plasma HDL cholesterol (HDL - C) metabolism in the progression of atherosclerosis; the genetic epidemiology of the metabolic syndrome and low HDL - C levels established by the Turkish Heart Study.

Dr. Toal is also of the opinion that our personal skin microbiome is influenced by several genetic and environmental factors, explaining that oil secretion, pH levels, moisturization, and the products we use on our skin help or hurt these bacteria.

Scientists at the University of Colorado led by psychologist Richard K. Olson have explored the relationship between IQ levels and genetic and environmental influences on RD.. They found that genetic influences tend to be more important for children with RD who exhibit relatively high IQ scores, while environmental influences tend to be more important for children with RD who possess relatively low IQ scores.

This stabilization was due to: 1) Social effects of globalization that reduced reproductive rates below replacement levels, 2) Several genetic engineering disasters between 2020 and 2035 that killed tens of millions of people, 3) A nuclear exchange in the MidEast in 2021 that lead to a mini - «nuclear winter,» cutting average temperatures by five degrees for a year, and 4) A punitive tax on non-renewable carbon - based energy quadrupled costs and led to more efficient use of energy resources.

Together, these genetic factors were very strong influences on the levels of SxAnxDep reported in common by parents and twins with heritability estimates, correcting for rater - and time - specific effects, ranging from 72 % to 89 %.