Sentences with phrase «on a molecular level in»

Not exact matches

Commenting on Whitehead's doctrine of structured societies at the cellular level, John Cobb remarks: «Whitehead at that point was forced to explain the order in the cell in terms of its molecular structure, to which spontaneity was denied, and to explain the life of the cell in terms of the events in its empty space, which he depicted as radically unordered.

The ability of biology to detail the organisation and constitution of life - forms, not just on a cellular level, but now also on a genetic and molecular level, and its description of how such factors canaffect the global behaviour of an organism, should be taken into account in the theological and philosophical discussion of free will, individual identity / personality, conscience, the soul, and other areas concerning human behaviour, especially in regard to morality.

Given a system or composite of individuals, all on a comparable level, for instance molecular or cellular, then in some cases, given integration of activities (thus molecules in a cell, or cells in a vertebrate animal), there may be what Leibniz called a «dominant monad» or what Whitehead calls a «society of presiding occasions.»

«The Poverty Clinic,» [PDF] March 21, 2011 «In the view of Burke and the researchers she has been following, many of the problems that we think of as social issues — and therefore the province of economists and sociologists — might better be addressed on the molecular level.»

Libbrecht is interested in what happens on a molecular level when ice crystals form, but he sees it as an old - fashioned scientific pursuit: «It's really like doing science 100 years ago,» he says, in that he's studying a mystery inherent in the mundane and familiar snowflakes that flutter from the sky each winter.

The researchers hope these study findings will aid in understanding the complex human reproductive cycle and the occasional problems that originate on a molecular level.

Associate professor Mary - Ellen Taplin, of the Dana - Farber Cancer Institute, Boston, USA, will tell the 26th EORTC - NCI - AACR Symposium on Molecular Targets and Cancer Therapeutics in Barcelona, Spain, that galeterone was well tolerated by patients in the ARMOR2 trial, and also lowered PSA levels in a subset of men with CRPC that was resistant to other drugs that target the cancer, such as enzalutamide and abiraterone.

In the 1990s the invention of atom - scale carbon cylinders known as carbon nanotubes convinced many scientists that nanotechnology — the manufacture of materials on the molecular level — was poised to revolutionize computing, medicine, and other fields.

«What we found is that on a molecular level, the complex I deficit is probably just the tip of the iceberg of a pervasive deficit in all energy genes.»

Rothenburg further said that on the population level, this is probably the best - known example for a host - virus coevolution in nature, but it lacked a molecular explanation until this study.

The new work shows that «hyperthermia in and of itself can cause these birth defects, and on a molecular level, here's how it happens,» Benner says.

Korley would like to follow up with more research on why, at a molecular level, brain injuries lower levels of BDNF in the blood and whether things known to increase BDNF levels — including exercise and omega - 3 fatty acids — could help treat TBIs.

And once I got into brain biology, it became clear you needed to study the brain on the cellular level, and once you began to understand aspects of behavior in the cellular level, you wanted to understand the molecular level.

«Our study is a nice example of how the understanding of a disease on the molecular and cellular level results in new therapeutic options.

«Increasingly in the life sciences, developments are based on an understanding of processes at the molecular level, even where the molecules are large and in complex systems,» says Ashmore, «so an increased hiring of folk with a thorough understanding of the fundamentals is taking place.»

A machine in University of Illinois chemistry professor Martin Burke's lab assembles complex small molecules out of simple chemical building blocks, like a 3 - D printer on the molecular level.

The study, which appears in the current issue of the journal Genome Biology, is the first to reveal on a molecular level how loneliness puts people at risk for disease, says Cole.

The next step in this line of investigation, already in development, is to learn how cellular responses vary, on a molecular level, among roots of flooded plants when the hormone is not present, which would make it possible to create a response model where this signaling path would play a key role.

We see manifold applications, such as studies of conformational changes in amyloid structures on the molecular level, the mapping of nanoscale protein modifications in biomedical tissue or the label - free mapping of membrane proteins.

The biologist has just received Japan's prestigious Kyoto Prize in Basic Sciences, honoring his groundbreaking exploration of evolution on a molecular level.

Scientists think plant cells living in space do not behave the same way as cells in plants on Earth, and the experiments will examine these changes on a molecular level.

«The computational approach allows us to model, right down to the atomic level, how small changes in protein sequence can have a major impact on signaling,» said MacDermaid, assistant professor of research at Temple's Institute for Computational Molecular Science.

He has worked in the biotech industry as a research scientist for over 11 years with a focus on emerging technologies including gene targeting in mice, molecular analysis of transgenes using GFP variants at the single cell level, and developing flow cytometry reagent kits to speed up assay development time for researchers.

In this study, researchers used the specimen collected in Taiwan 100 years ago and newly - discovered specimens to carry out detailed analysis on a molecular level, including DNA barcodinIn this study, researchers used the specimen collected in Taiwan 100 years ago and newly - discovered specimens to carry out detailed analysis on a molecular level, including DNA barcodinin Taiwan 100 years ago and newly - discovered specimens to carry out detailed analysis on a molecular level, including DNA barcoding.

«In this new study, we explain how iron - based dyes work on a molecular level.

The study involved a technique called recombineering to manipulate DNA at the molecular level, so as to remove and then reinsert the gene in various doses to see the effects on behaviour and metabolism.

At the ASTMH meeting, scientists launched the Worldwide Antimalarial Resistance Network (WWARN), a global database that will collect information on resistance in vivo and in vitro, drug levels in patients» blood, and molecular markers.

To peel away at the intricate layers that govern the development of neurons, a research team led by Chaolin Zhang, PhD, Assistant Professor in Systems Biology and Biochemistry and Molecular Biophysics and Hynek Wichterle, PhD, Associate Professor in Pathology & Cell Biology, Neuroscience, and Neurology, at the Center for Motor Neuron Biology and Disease, Columbia University Medical Center, focuses on a level of molecular regulation called alternative Molecular Biophysics and Hynek Wichterle, PhD, Associate Professor in Pathology & Cell Biology, Neuroscience, and Neurology, at the Center for Motor Neuron Biology and Disease, Columbia University Medical Center, focuses on a level of molecular regulation called alternative molecular regulation called alternative splicing.

The new study, published this month by Molecular Autism in a special issue on sex differences in autism, further shows a stronger correlation between the expression level of RORA and that of genes regulated by RORA in males.

If you zoom in on a snowflake, you'll see its six - sided symmetry mirrored at the molecular level.

Scientists do not yet fully understand how antibiotics work on the molecular level, but they think that the drugs are effective in part by introducing reactive oxygen to bacterial cells, which damages key cellular structures.

This program, McKnight Technological Innovations in Neuroscience Awards, focuses on «how technology may be used or adapted to monitor, manipulate, analyze, or model brain function at any level, from the molecular to the entire organism.»

But then, one day I was sitting in biology class and my teacher explained that every living being on the face of this earth is the same at the molecular level: We all have A, T, G, and C.

«Our contribution was to conduct molecular dynamics simulations where we follow the trajectory of the electrons and atoms in time and observe what's going on at the atomistic level,» Balbuena said.

Not only were levels of metabolic compounds different, but the expression of certain genes involved in metabolism was turned up, and the epigenome of the cells — molecular markers on DNA that change gene expression on a broader scale — was altered.

Published in the Nov. 21 edition of Cell, the findings will help scientists understand how genetic changes cause autism on a molecular level and prioritize targets for future studies.

Dr. Sonntag studies this concept on the molecular and cellular level using a translational research approach that integrates the analysis of human material, such as postmortem brains, primary cell systems, and neural cell populations generated from patients» - or healthy individuals» - derived induced pluripotent stem cells (iPSC), or induced neurons (iNs), in combination with molecular, biochemistry, and lentivirus - mediated gene - engineering technologies.

Now a team of scientists may have found a way to stabilize Factor VIIIa in solution coaxing the subunits to form a disulfide bond — like handcuffing them together on the molecular level.

Consequently, the level of access offered by the core varies from consultation and advice on specific aspects of projects, through training on particular techniques and / or instruments available in the core, to complete molecular analyses from sample preparation to final data analysis.

With JWST, a few hours of integration time will be enough to detect Earth - like levels of water vapor, molecular oxygen, carbon dioxide and other generic biosignatures on planets orbiting a white dwarf; beyond that, observing the same planet for up to 1.7 days will be enough to detect the two CFCs in concentrations of 750 parts per trillion, or 10 times greater than on Earth.

Research in the lab of Edward P. Feener, Ph.D., Investigator in the Section on Vascular Cell Biology and Director of the Proteomics Core at Joslin Diabetes Center and an Associate Professor of Medicine at Harvard Medical School, now has shown that a substantial percentage of patients with DME do not have high levels of VEGF in the fluid inside their eyes but do have high levels of a protein called PKal (plasma kallikrein) and associated molecules that are key players in an inflammatory molecular pathway involved in the disease.

The consequences of gene extinction on DM1 phenotype is then monitored at the molecular level by quantitative PCR or at the cellular level by high content screening in 96 or 384 - well plate format.

Understanding why this complexity is required, how and when distinct lipid molecules interact with proteins and how these interactions are in turn modulated by lipid metabolism will be critical for elucidating how biological membranes function on a molecular level.

Research in drug action at the molecular level depends primarily on understanding and defining the physical / chemical interaction between the drug and its receptor, and then understanding how to connect this interaction to the pharmacological response.

The CellDevo Track focuses on the study of molecular mechanisms in eukaryotic cells and their role in tissue formation, with the level of analysis ranging from single molecules to single cells, from cells to tissues, and from tissues to whole organisms.

These findings, reported today in Nature Neuroscience, also offer newfound understanding as to what goes on at the molecular level when this process becomes disrupted.

The authors stressed that their findings, which combine basic science with large - scale analysis of genetic studies, depended on an unusual level of cooperation among experts in genetics, molecular biology, developmental neurobiology and immunology.

The symposium will focus on the roles of the major enzymes participating in metabolism of xenobiotics including carcinogens and drugs — the membrane monooxygenase systems containing cytochromes P450 — and highlight the key advances in their mechanisms of action at the molecular level.

A key to a mechanistic understanding is the ability to observe membrane organization with a spatial resolution on the molecular level, a temporal resolution in the micro-second range and sensitivity down to the single molecule without disturbing the system (noninvasive).

Vanderbilt neuroscience was built in part by psychopharmacologists who helped define — at the molecular level — the effects of drugs on the brain and nervous system.