Sentences with phrase «on a trial basis earlier»

Arsenal tried to bring in Sobhy on a trial basis earlier this year, which was rejected, and he is now the subject of a bid by Stoke City.

Not exact matches

The modifications and changes of the Oxford technique were made on a trial - and - error basis by the early members of what came to be called AA.

Although not directly comparable, our findings are in broad agreement with those from routine data in Scotland that have indicated a positive association between Baby Friendly accreditation, but not certification, and breastfeeding at 1 week of age.17 Our findings reinforce those of Coutinho and colleagues who reported that high exclusive breastfeeding rates achieved in Brazilian hospitals implementing staff training with the course content of the Baby Friendly Hospital Initiative were short - lived and not sustained at home unless implemented in combination with post-natal home visits.35 Similarly in Italy, training of staff with an adapted version of the Baby Friendly course content resulted in high breastfeeding rates at discharge, with a rapid decrease in the days after leaving hospital.36 In contrast, a cluster randomized trial in Belarus (PROBIT) found an association between an intervention modelled on the Baby Friendly Initiative with an increased duration of breastfeeding37 an association also reported from an observational study in Germany.38 Mothers in Belarus stay in hospital post-partum for 6 — 7 days, and in Germany for 5 days, with post-natal support likely to be particularly important in countries where mothers stay in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based intervention.

Data derived from two randomized trials with primiparous women from Honduras, one based on low birth weight and the other on normal birth weight infants, show that infants who were exclusively breastfed for six months (vs. four months) began to crawl earlier.5 In addition, the normal birth weight trial showed that babies who were exclusively breastfed for six months were significantly more likely to be walking by one year compared with those who were exclusively breastfed for four months (60 % vs. 39 %).

Effectiveness of home based early intervention on children's BMI at age 2: randomised controlled trial

Now, the testimony of two witnesses at a federal trial unfolding in Newark has placed Cuomo in close proximity to what has principally been a New Jersey - based narrative of lies, retribution and planned cover ups as early as October of 2013 — just weeks after the sudden closure of several lanes on the New Jersey side of the George Washington Bridge.

Thomas Smith, who studies the epidemiology of malaria at the Swiss Tropical Institute in Basel, says it may be premature to say exactly what the efficacy is based on this early data from the trial, which is still ongoing.

Clinical trials for targeted therapies, selected on the basis of the genomic tests, are scheduled to begin in early 2007.

Dr. Sparano continued: «This is the first prospectively conducted clinical trial evaluating this assay — or any multigene expression assay for that matter — in which patients with early stage breast cancer were uniformly treated based on their assay results.

White and colleagues will work with other collaborators at the Cancer Institute to develop early - phase patient clinical trials based on the findings from this study in the near future.

Based on the study published, a larger randomized trial is underway in Tanzania to determine if DAR - 901 prevents the earliest stage of infection with tuberculosis, before symptoms are apparent.

An advisory panel to the FDA recommended approval of Provenge on the basis of good early clinical results, but the FDA instead requested more information last May after a second phase III clinical trial seemed more equivocal.

Our group has 3 major goals: Develop novel therapeutic approaches based on centrosomal clustering To further develop our first prototype inhibitors of centrosomal clustering preclinically and to establish a robust and specific high throughput small molecule screen Discover key events in myeloma pathogenesis To investigate the pivotal transition from the pre-malignant, asymptomatic to malignant, symptomatic stages of plasma cell dyscrasias in order to understand the pathophysiology and thereby identify novel targets Translate small molecule therapeutics from bench to clinical trials To evaluate novel agents in the preclinical setting and to initiate early phase clinical trials in hematologic malignancies with focus on multiple myeloma

The drug was approved based on efficacy and safety results from a phase III trial presented earlier this year at the 2015 American Society of Clinical Oncology Annual Meeting.

The trial was stopped early based on health risks that exceeded health benefits over an average follow - up of 5.2 years.

Based primarily on clinical trials led by Arjun V. Balar, MD, assistant professor of medicine and director of the Genitourinary Medical Oncology Program, the FDA approved atezolizumab (Tecentriq ®) and pembrolizumab (Keytruda ®) as first - line treatments for these particularly frail patients with advanced bladder cancer in early 2017.

The Center for Cancer Targeted Therapies (C2T2) integrates a phase I - Ib / early clinical trials program, a precision cancer medicine infrastructure with expertise on tumor tissue - based state - of - the - art molecular methods, and a core resource with novel non-invasive functional imaging methods.

In order to more reliably identify high - risk patients as early as possible, the researchers used data from 159 patients with FL who had participated in three prospective trials, to build a prognostic model based on TMTV and EOI PET.

Some important studies include: • Beneficial effects of a high carbohydrate, high fiber diet on hyperglycemic diabetic men (1976) • Response of non-insulin-dependent diabetic patients to an intensive program of diet and exercise (1982) • Diet and exercise in the treatment of NIDDM: The need for early emphasis (1994) • Toward improved management of NIDDM: A randomized, controlled, pilot intervention using a low fat, vegetarian diet (1999) • The effects of a low - fat, plant - based dietary intervention on body weight, metabolism, and insulin sensitivity (2005) • A low - fat vegan diet improves glycemic control and cardiovascular risk factors in a randomized clinical trial in individuals with type 2 diabetes (2006) • A low - fat vegan diet and a conventional diabetes diet in the treatment of type 2 diabetes: a randomized, controlled, 74 - wk clinical trial (2009) • Vegetarian diet improves insulin resistance and oxidative stress markers more than conventional diet in subjects with Type 2 diabetes (2011) • Glycemic and cardiovascular parameters improved in type 2 diabetes with the high nutrient density (HND) diet (2012)

1935 Effects of the high carbohydrate - low calorie diet upon carbohydrate tolerance in diabetes mellitus 1955 Low - fat diet and therapeutic doses of insulin in diabetes mellitus 1958 Effect of rice diet on diabetes mellitus associated with vascular disease 1976 Beneficial effects of a high carbohydrate, high fiber diet on hyperglycemic diabetic men 1977 Effect of carbohydrate restriction and high carbohydrates diets on men with chemical diabetes 1979 High - carbohydrate, high - fiber diets for insulin - treated men with diabetes mellitus 1981 High carbohydrate high in fibre diet in diabetes 1982 Response of non-insulin-dependent diabetic patients to an intensive program of diet and exercise 1983 Long - term use of a high - complex - carbohydrate, high - fiber, low - fat diet and exercise in the treatment of NIDDM patients 1994 Diet and exercise in the treatment of NIDDM: the need for early emphasis 1999 Toward improved management of NIDDM: A randomized, controlled, pilot intervention using a lowfat, vegetarian diet 2005 The effects of a low - fat, plant - based dietary intervention on body weight, metabolism, and insulin sensitivity 2006 A low - fat vegan diet improves glycemic control and cardiovascular risk factors in a randomized clinical trial in individuals with type 2 diabetes 2006 Effect of short ‐ term Pritikin diet therapy on the metabolic syndrome 2009 A low - fat vegan diet and a conventional diabetes diet in the treatment of type 2 diabetes: a randomized, controlled, 74 - wk clinical trial

As I mentioned earlier, the relaxation response has mostly been studied in terms of mindfulness meditation so here is a snapshot of what scientists are finding through highly credible, randomized controlled trials on mindfulness based stress reduction programs.

Irate that columnist George Will had questioned the benefits of early childhood education in a throwaway line in paragraph 15 of an op - ed, Heckman wrote, «Those benefits, quoted by President Obama this year, come from my evidence - based analysis of more than 30 years of data from the Perry Preschool program... It is as good a trial for effectiveness as those we currently rely on to evaluate prescription and over-the-counter drugs.»

A # 5 million investment to trial evidence - based home learning environment (HLE) support programmes in the north of England, which focus on early language and literacy, was also announced.

Not one of the studies that has suggested long - term positive impacts of center - based early childhood programs has been based on a well - implemented and appropriately analyzed randomized trial, and nearly all have serious limitations in external validity.

VSCC driving tests — Tom Threfall out and about with the light cars and Edwardians of the VSCC / London to Brighton Run — We were at Brighton to photograph the arrivals / VSCC Welsh Trial — A dampish but well - supported affair according to Tom Threlfall / 1929 Post office van — The editor tries a restored Morris light van that originally worked the Post Office / Aster and Arrol - Aster — The story of an Anglo - Scottish alliance by Michael Worthington Williams / Singer Junior — How Berni Jacobson built a Brooklands replica based on an early Singer 8hp chassis / Supercharged BNC — Part two of the story of this French cyclecar that became a full blown racer.

Having made adjustments based on sentiment and community data coming out of the beta and early trials, we ultimately made the decision to pull in - game purchases out of the game prior to launch.

There are, of course, earlier cases where an appeal was allowed on the basis that the decision of the trial judge was not truly a judicial decision.

Earlier this month, a federal appellate court issued an opinion dismissing a plaintiff's appeal based on the plaintiff's failure to object to an alleged error at trial.

The MOL responded to McNeil by implementing a process by which it routinely initiated CPIC checks on its inspectors once occupational health and safety matters were set down for trial (and earlier based on a defence request).

CORRECTION: An earlier version of this post incorrectly stated that Kansas - based reporter Ron Sylvester would be reporting on a trial in Colorado.

By the way, March wasn't much better for Google with a preliminary ruling against Motorola's ITC complaint against the Xbox, Nokia's refusal to grant a license to its allegedly VP8 - essential patents, Nokia's progress toward its first Android patent license deal, and a trial based on which Microsoft may very well win (in early June) a German injunction not only against Motorola but also its parent company, Google, with respect to Google Maps.

The trial court ruled in favor of the defendants early in the case proceedings, finding that the plaintiff could not sue the government for its alleged negligence, based on sovereign immunity grounds.

Earlier, among other matters, he obtained a full defense jury verdict as lead trial counsel in a case on behalf of the New York City Law Department; served as lead counsel in an appeal where the court vacated a first degree robbery conviction of a client on the basis of ineffective assistance of counsel (People v. Cyrus, 48 A.D. 3d 150 (1st Dept. 2007)-RRB-; and was co-lead counsel on the submission of an amicus brief on First Amendment issues with the United States Supreme Court.

At trial, Vancouver Criminal Defence Lawyer Emmet J. Duncan challenged the admission of the fingerprint match, on the basis that the original fingerprints, which police had taken from Client three years earlier when Client was a youth, were taken in violation of his rights under the Charter of Rights and Freedoms.

The lower cost and time commitment means that you can take an opportunity to conduct a mock jury trial early in your case and make strategy decisions based on what you learn.

The trial judge determined that he had this new evidence that indicated a better read of the intention of Section 121, and on that basis, he said that this earlier Supreme Court decision was wrong.

As stated earlier, most credit insurance is on a beginning free trial basis.

Though eNPS was earlier launched on a trial basis and the use of Aadhaar as eKYC was allowed, soon it got discontinued, due to the restriction imposed by the Supreme Court on the use of Aadhaar as eKYC.

SharpestMinds matches up students that apply on their site with companies where they can work on a trial basis, building up that early relationship that could lead to a job down the line.

«Verizon, which was early to trial this technology — based on high - frequency millimeter - wave spectrum — has been particularly vocal about promoting this as «5G,» since it allows it to claim it's providing 5G service earlier than its competitors.

The Government has stated that the new arrangements are based on «the early learnings» from the COAG whole of government community trials as well as the principle findings of the ATSIC Review.

Although the COAG trials are progressing well, it is too early to determine whether the trials should form the basis of a new model of service delivery in Victoria or wider Australia... It is premature to build on the COAG trials given they are still in their developmental phase and are based on disparate models of operation across diverse jurisdictions.

When the longitudinal study was funded by the National Institute on Drug Abuse in 1985, school - based substance abuse prevention research trials had been limited to studies of social influence resistance curricula provided to students in grades 5 through 10.3 In this context, reviewers desired that the study include a condition assessing effects of only 2 years of intervention in the late elementary grades as well as effects of the full intervention, since they questioned whether intervention in the early elementary grades was necessary.

At the point of referral to the trial, families were randomized to either Early Start or control series based on a computer - generated series of random numbers, and no blinding to assignment was undertaken.

This trial investigated the effectiveness of an existing parenting programme offered on a universal basis in deprived areas in the context of an open access early years programme offering a wide range of support for parenting.

To date, the immediate and lasting positive effects of quality care on language, cognitive development, and school achievement have been confirmed by converging findings from large, reasonably representative longitudinal studies and smaller, randomized trials with long - term follow - ups.1, 2,9 - 13 Contributors to this knowledge base include meta - analytic reviews of interventions and large longitudinal studies conducted in several countries.1, 2,14,15 Comprehensive meta - analyses now establish that effects of early care decline, but do not disappear, and when initial effects are large, long - term effects remain substantial.1, 2 Null findings in cognitive and social domains in a few studies may reasonably be attributed to the limitations inherent to their designs, samples, and measures.

Effects of an interactive mHealth innovation for early detection of patient - reported symptom distress with focus on participatory care: protocol for a study based on prospective, randomised, controlled trials in patients with prostate and breast cancer.

It is based on the hypothesis that inaccurate and unhelpful beliefs, ineffective coping behaviour, negative mood states, social problems, and pathophysiological processes all interact to perpetuate the illness.8 9 Treatment aims at helping patients to re-evaluate their understanding of the illness and to adopt more effective coping behaviours.7 8 9 An early uncontrolled evaluation of this type of treatment produced promising results in many patients but was unacceptable to some.10 Two subsequent controlled trials found cognitive behaviour therapy to offer no benefit over non-specific management.11 12 However, the form of cognitive behaviour therapy evaluated may have been inadequate.

On the basis of these findings, the trial results were analyzed with an intention - to - treat paradigm in which the outcomes for the Early Start series were compared with those of the control series.

The randomised controlled trial, currently underway across sites in Victoria and Tasmania, is based on the Maternal Early Childhood Sustained Home - visiting (MECSH) program and incorporates additional modules to help parents care for and respond to their children, and create a supportive home learning environment.