Assessment of order effects were of interest as they permitted examination of prior sleep history
on ad libitum food intake and energy metabolism (i.e., continuous adequate 9 - h sleep opportunities followed by 5 - d sleep restriction and 5 - d sleep restriction followed by 5 - d, 9 - h adequate / recovery sleep opportunities).
The results may have been different
on an ad libitum (eat until fullness) diet.
Sufficient food was provided
on this ad libitum high - protein diet to allow subjects to consume up to 15 % more than their weight - maintaining daily caloric intake.
Not exact matches
Mice were housed at the University of Colorado Anschutz Medical Campus or at the German Institute of Human Nutrition in ventilated cages
on a 12 h / 12 h light / dark cycle and fed standard chow
ad libitum.
Acute ethanol as a 2nd «hit»: Here we employ a model in which acute binge alcohol is administered in addition to chronic
ad libitum exposure (variously called acute
on chronic, Gao - binge, or NIAAA model).
All mice were housed in our Association for Assessment and Accreditation of Laboratory Animal Care - accredited barrier facility
on a 12 h light / dark cycle, and given
ad libitum access to food (NIH31 Diet, Harlan no. 7917) and water.
Mice were weaned at 3 weeks, maintained
on a 12 - hour light cycle, and had
ad libitum access to water and a standard rodent chow diet (PicoLab Rodent Diet 20, 5053; LabDiet) or a high - fat diet (TD.88137; Harlan Teklad).
Mice were raised
on a 12 - h light / dark cycle, with food and water available
ad libitum and were housed in groups of two to three per cage.
Compared to
ad libitum fed controls, rodents maintained
on IER (100 % ER / alternate days) for periods of 12 to 24 weeks typically exhibit lower post-treatment levels of fasting glucose 14, 16, 17, 29 and insulin.16, 17, 29 Using this particular IER protocol, Jiang et al28 have also demonstrated an increase in oral glucose tolerance and tissue insulin sensitivity (measured using a hyperinsulinemic - euglycemic clamp) after four weeks in healthy rats.
Individuals are then asked to consume an
ad libitum or euenergetic intake
on non-restricted days.
Design: Appetite, caloric intake, body weight, and fat mass were measured in 19 subjects placed sequentially
on the following diets: a weight - maintaining diet (15 % protein, 35 % fat, and 50 % carbohydrate) for 2 wk, an isocaloric diet (30 % protein, 20 % fat, and 50 % carbohydrate) for 2 wk, and an
ad libitum diet (30 % protein, 20 % fat, and 50 % carbohydrate) for 12 wk.
Covert manipulation of the ratio of medium - to long - chain triglycerides in isoenergetically dense diets: effect
on food intake in
ad libitum feeding men.
Protein deficiency is a strong driver of appetite, especially during pregnancy, so it's likely that if the mice had been allowed to feed
ad libitum there would have been no problems
on a 10 % protein chow.
Ad libitum food intake
on a «cafeteria diet» in Native American women: relations with body composition and 24 - h energy expenditure
Replacement of dietary fat by sucrose or starch: effects
on 14 d
ad libitum energy intake, energy expenditure and body weight in formerly obese and never - obese subjects.
While alternate - day fasting leads to calorie restriction over a two - day period in many rodent species, in some strains of mice, the animals managed to compensate for the calorie deficit created
on fast days by increasing their intake
on feast days twofold and thus keeping the total calorie intake over a two day period at the same level as in mice fed an
ad libitum diet (17).
Furthermore, when myocardial infarction was induced in rats maintained
on an alternate - day fasting diet, reduced infarction size, improved cardiac function, and increased survival was observed, compared to rats fed
ad libitum (24,33,43).
Furthermore, in an animal model of Huntington's disease, prolonged survival, reduced disease - associated weight loss and improved motor function was observed in animals
on an alternate - day fasting diet compared to animals fed
ad libitum (49).
Anson et al. showed that mice
on alternate - day fasting regimen who consume the same amount of food in a 48 - hour period as mice fed
ad libitum, decreased glucose and insulin concentrations to a similar degree as did mice
on daily calorie restriction despite maintained energy intake and body weight (17).
However, C57BL / 6 mice maintained
on the same alternate - day fasting regimen consume similar food quantities in a 48 - hour time period and maintain body weights similar to that of mice fed
ad libitum (17).
They propose that animals
on alternate - day fasting diets increase life span compared to those fed
ad libitum (15,40).
When mice with progressive demyelinating disorders of the peripheral nervous system were put
on an alternate - day fasting diet regime, hampered disease progression was observed as indicated by improved nerve morphology and performance compared to mice fed
ad libitum (37).
Rats fed
on alternate days showed preserved kidney function as demonstrated by preserved glomerular filtration rate and renal plasma flow, compared to rats fed
ad libitum.
When an alternate - day fasting diet is implemented, overall calorie restriction and weight reduction occurs in most rodent species, indicating that the restriction
on the fasting day isn't compensated fully
on feasting days when food is offered
ad libitum (18 - 34).
Mice
on a 60 % fat diet were far healthier eating IF than
ad libitum, but also fitter than mice given a 13 % fat diet as control.
Scientists have gone
on to put people
on low fat high carbohydrate diets (
ad libitum, meaning completely unrestrained intake of carbohydrates), and the results are as good or better than the ADA recommend diet which restricts carbohydrates from entering the bloodstream to begin with.
In ADF, participants fast every other day and eat
ad libitum on in - between days (25).
Furthermore, why overeating during
ad libitum food availability occurred in the 9 - h condition is unclear, but perhaps not unexpected based
on the availability and palatability of food provided (36), and comparisons of other feeding models during adequate versus insufficient sleep are needed.
Rats were fed
ad libitum, meaning they could eat as much as they liked; they chose to eat twice as many calories
on the ketogenic diet.
Adhering to these traditional concepts the US Department of Agriculture has concluded that diets, which reduce calories, will result in effective weight loss independent of the macronutrient composition, which is considered less important, even irrelevant.14 In contrast with these views, the majority of
ad -
libitum studies demonstrate that subjects who follow a low - carbohydrate diet lose more weight during the first 3 — 6 months compared with those who follow balanced diets.15, 16, 17 One hypothesis is that the use of energy from proteins in VLCKD is an «expensive» process for the body and so can lead to a «waste of calories», and therefore increased weight loss compared with other «less - expensive» diets.13, 18, 19 The average human body requires 60 — 65 g of glucose per day, and during the first phase of a diet very low in carbohydrates this is partially (16 %) obtained from glycerol, with the major part derived via gluconeogenesis from proteins of either dietary or tissue origin.12 The energy cost of gluconeogenesis has been confirmed in several studies7 and it has been calculated at ∼ 400 — 600 Kcal / day (due to both endogenous and food source proteins.18 Despite this, there is no direct experimental evidence to support this intriguing hypothesis;
on the contrary, a recent study reported that there were no changes in resting energy expenditure after a VLCKD.20 A simpler, perhaps more likely, explanation for improved weight loss is a possible appetite - suppressant action of ketosis.
C) The rats were allowed to eat
ad libitum on the IF days, but they simply did not meet their caloric requirements this way.
Effects of a high - protein ketogenic diet
on hunger, appetite, and weight loss in obese men feeding
ad libitum.
For the
ad libitum feeding days, participants were given a monetary allowance ($ 25) to purchase foods and beverages of their choice to consume in the lab
on days 5 and 6.
A study carried out
on 48 Labrador Retrievers compared dogs fed
ad libitum, with puppies that were fed
on a more restricted diet.
Control dogs fed 1.1 % calcium and 0.9 % phosphorus (all
on a dry matter basis) were fed
ad libitum (n = 10) or in restricted amounts (n = 6); dogs fed high calcium (3.3 %) diets received either 0.9 % phosphorus (n = 6) or 3.0 % phosphorus (n = 6); dogs fed low calcium (0.55 %) diets received either 0.9 % phosphorus (n = 5 + 6) or 0.5 % phosphorus (n = 8).