Sentences with phrase «on allelic»

Analyses were conducted using aggregate published data on allelic frequency of 5 - HTTLPR, cultural values of individualism — collectivism and global prevalence of historical and contemporary pathogen prevalence, with nation as the cultural unit of analysis.

Data on allelic frequency of the 5 - HTTLPR from 50 135 individuals living in 29 countries (Argentina, Australia, Austria, Brazil, Denmark, Estonia, Finland, France, Germany, Hungary, India, Israel, Italy, Japan, Korea, Mexico, the Netherlands, New Zealand, Poland, People's Republic of China, Russia, South Africa, Singapore, Spain, Sweden, Taiwan, Turkey, UK and USA) were compiled from 124 peer - reviewed publications (see table S1 and methods in electronic supplementary material for further detail).

Analyses were conducted using aggregate published data on allelic frequency of 5 - HTTLPR, cultural values of individualism — collectivism and global prevalence of anxiety and mood disorders, which refers to bipolar disorder, dysthymia and major depressive disorder defined by DSM IV / CIDI criteria in the 2008 World Health Organization (WHO) survey, with nation as the cultural unit of analysis.

The authors conclude that»... by 4400 years ago, early farmers had already had a substantial homogenizing effect on allelic diversity at three genes associated with maize morphology and biochemical properties of the corn cob.»

Not exact matches

Junji Hirota at Tokyo Tech and team focused on discovering a long - range enhancer for a large gene cluster, finding an evolutionary conserved sequence motif in mammalian evolution, and elucidating enhancer - dependent allelic preference or exclusion mechanism for odor - detecting receptor genes.

Therefore, we assessed the genotype and allelic frequency of this SNP in elite athletes participating in 11 different sports differing in dependence on endurance.

Many of the allelic effects in the QTL were driven by the two founders with underrepresented subspecific origins, including a QTL on chromosome X for infertility that was driven by the PWK / PhJ haplotype.

«Some are strong and some more moderate; there is an allelic series where the degree to which genes are turned on and off varies depending on which guide RNA we use.

He has focused on leveraging allelic expression data to quantify regulatory variation within individuals.

Please contact [email protected] for more information on the C / C mouse and other SMA Foundation allelic series mice.

Such an allelic chromatin organization might be present at other DMRs as well, and a recent study by Schweizer et al. (2) shows that the imprinting - control region in the 5 % portion of the SNRPN gene has strong hypersensitive sites on the unmethylated maternal chromosome only.

Based on differences in imputed nsSNP allelic frequencies in different genetic backgrounds, likelihood measurements were calculated for European relative to African genetic backgrounds, with distinct patterns emerging as a function of genetic background.

The allelic diversity sampled on the Channel Islands was mostly a subset of the diversity on the mainland, because only 2 of the 19 private alleles found in the study were private to the islands.

We examined the influence of a common allelic variation in the dopamine receptor D4 (DRD4) gene and caregiver quality on temperament in early childhood.

To further determine the specificity of the mediating role of collectivistic cultural values on the association between allelic frequency of the 5 - HTTLPR and mental health disorders, we also conducted regression of mediation on 5 - HTTLPR, individualism — collectivism and two mental health disorders included in the 2008 WHO Mental Health Survey, but not previously associated with the 5 - HTTLPR, namely substance abuse and impulse control.

More importantly, however, it will be crucial to determine (1) how this functional locus interacts with the allelic expression imbalance markers downstream (and which the actual locus conferring allelic expression imbalance is, see in what follows)(2), what the relative contribution to a net effect on serotonin transporter gene expression is in vivo and (3) how (if at all) this translates into protein abundance and actual genetically determined differential functioning of the serotonergic synapse.

The allelic variant, RS3 334, is associated in men, but not women, with a lower bonding quality with the partner (characterized by lower scores on the partner bonding scale and a greater likelihood of reporting martial problems)(Walum et al., 2008).

CONCLUSIONS: These results suggest that the behavioral expression of allelic variation in MAOA activity is sensitive to social experiences early in development and that its functional outcome might depend on social context.

Next, the primary research questions were addressed by examining the moderating effects of allelic group on task - specific brain activation.

During the outcome phase (during presentation of feedback), the contrast of interest was the effect of allelic groups on differences in brain activation for reward versus non-reward trials.

During the anticipation phase (the time between presentation of cues and potential reward receipt), the contrast of interest was the effect of allelic group on differences in brain activation for incentive versus non-incentive trials.