Sentences with phrase «on antibody probes»

Olink's Proximity Extension Assay (PEA) detection technology is based on antibody probes linked to DNA tags.

Not exact matches

The residues altered were selected based on the observation that the three VHH described herein, B9, A14 and B21, bind to the RSC3 probe that was used to isolate the VRC01 - class of human CD4 binding site broadly neutralizing antibodies (Fig. 2) and that previously the introduction of an aromatic residue into the VRC01 - like antibody NIH45 - 46 resulted in increased breadth and potency [38].

The researchers then used a dynamic force - scanning probe microscope for single - molecule force spectroscopy as well as antibody - recognition force microscopy (Ig - RFM) to map the locations of MtrC and OmcA on the surface of live Shewanella cells.

The cell assays are based on blood samples or tissue biopsies from these patients, and readouts are either specific, such as antibody production or the production of proinflammatory cytokines, or wider, such as proteomic effects of the probes.

Current research applications focus on new approaches to a) drug and probe development for neurodegenerative disorders and diseases including Schizophrenia, Alzheimer's, and Parkinson's, b) understanding the structural determinants of antidepressant binding to neurotransmitter transporters, c) cardiac arrhythmia as caused by the complex interplay of potassium channel regulation and drug interactions, d) multidrug resistance in cancer and bacterial cells related to multidrug transporter proteins, and e) structural basis of viral infections and antibody activity.