Sentences with phrase «on as a major factor»

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

«I worked at Google for 3 years and it was very difficult to leave but there was one major factor that helped me make the decision - the impact I could ever have on the business as an individual was minimal.

«The major factor acting as a drag on long - term upside potential is the surge in U.S. shale supply.

There are worrying social impacts downstream as a result of these factors: a lowered marriage rate, more adult children cohabiting with their parents, a reduction in the birthrate, and young people holding off on major life events such as starting relationships or home ownership.

Factors that could cause actual results to differ include general business and economic conditions and the state of the solar industry; governmental support for the deployment of solar power; future available supplies of high - purity silicon; demand for end - use products by consumers and inventory levels of such products in the supply chain; changes in demand from significant customers; changes in demand from major markets such as Japan, the U.S., India and China; changes in customer order patterns; changes in product mix; capacity utilization; level of competition; pricing pressure and declines in average selling prices; delays in new product introduction; delays in utility - scale project approval process; delays in utility - scale project construction; delays in the completion of project sales; continued success in technological innovations and delivery of products with the features customers demand; shortage in supply of materials or capacity requirements; availability of financing; exchange rate fluctuations; litigation and other risks as described in the Company's SEC filings, including its annual report on Form 20 - F filed on April 27, 2017.

Factors that could cause actual results to differ include general business and economic conditions and the state of the solar industry; governmental support for the deployment of solar power; future available supplies of high - purity silicon; demand for end - use products by consumers and inventory levels of such products in the supply chain; changes in demand from significant customers; changes in demand from major markets such as Japan, the U.S., India and China; changes in customer order patterns; changes in product mix; capacity utilization; level of competition; pricing pressure and declines in average selling prices; delays in new product introduction; delays in utility - scale project approval process; delays in utility - scale project construction; continued success in technological innovations and delivery of products with the features customers demand; shortage in supply of materials or capacity requirements; availability of financing; exchange rate fluctuations; litigation and other risks as described in the Company's SEC filings, including its annual report on Form 20 - F filed on April 20, 2016.

Factors that could cause actual results to differ include general business and economic conditions and the state of the solar industry; governmental support for the deployment of solar power; future available supplies of high - purity silicon; demand for end - use products by consumers and inventory levels of such products in the supply chain; changes in demand from significant customers; changes in demand from major markets such as Japan, the U.S., India and China; changes in customer order patterns; changes in product mix; capacity utilization; level of competition; pricing pressure and declines in average selling prices; delays in new product introduction; delays in utility - scale project approval process; delays in utility - scale project construction; cancelation of utility - scale feed - in - tariff contracts in Japan; continued success in technological innovations and delivery of products with the features customers demand; shortage in supply of materials or capacity requirements; availability of financing; exchange rate fluctuations; litigation and other risks as described in the Company's SEC filings, including its annual report on Form 20 - F filed on April 27, 2017.

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commfactors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commfactors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commfactors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange CommFactors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

It is difficult to take proper account of the myriad relevant factors in making decisions on even relatively minor matters like diet, let alone such major concerns as foreign policy or population control.

The Republicans lost in 2012 with Ryan as their vice presidential candidate, but the GOP's boldness in taking on a major entitlement does not seem to have been a major factor.

8 February 2013 Media Statement Australian beverage industry responds to French study on consumption of artificially and sugar sweetened beverages and incident type 2 diabetes According to the World Diabetes Federation, ultimately the major risk factors for developing type 2 diabetes is lifestyle factors, including obesity and sedentary behaviour, as well as family history, age -LSB-...]

My stating that a decision made on Dotson will have his health as a major determining factor doesn't mean that I'm dismissing poor play by other players.

Kuchar has been a trendy pick at all three majors, but last week was another disappointment as the lanky Grey Goose pitchman never factored on the weekend.

That will have been a major blow for the 28 - year - old on a personal level as he'll be desperate to feature more prominently and consistently, but that has undoubtedly been a factor in the ongoing speculation linking him with an exit.

Most people depend on the television or video games for entertainment, which is one of the major factors in lifestyle diseases such as type II diabetes.

Additionally, in over half of these cases other major risk factors, such as smoke exposure or sleeping on soft surfaces, were present at the death scene.

Instead, the Pakistan which remained tried to carry on, pretending that it was still the land of South Asia's Muslims, just smaller... It never figured out why it should exist as a nation - state, and that combined with poor governance and major geostrategic factors have brought the country to a pass where its further dissolution is now argued increasingly in terms of when and how, not if.

I'm still miffed that Kerry Kenndy, supposedly Mary Kennedy's best friend, blamed Mary's suicide on depression that she'd had even before she married RFK Jr. — as if Mary's cheating husband who was stiffing her on court ordered payments wasn't a major factor in her depression.

«For us, the biggest distinguishing factor is that every major newspaper in the state endorsed Gelber, so that's a message we could get to voters in a few words in an ad, catching their attention on their phones as they're going into the polls,» Christian Ulvert, Gelber's campaign aide, told us.

In making her submission, the minister cum queen mother stated that the encounter with the movie producers revealed power outages, competition from foreign movies, TV stations showing recently released locally made movies and piracy as being the major factors killing the movie industry as little or no return is made on investment.

«For the UK's two million blind and partially - sighted people, as well as those with other disabilities or who are simply unfamiliar with their surroundings, a major factor stopping them from using buses is the lack of accessible information on board, such as next stop and final destination details.

A major factor in this high incidence of fuel poverty is lack of access to mains gas and dependence on more expensive oil as a heating fuel.

The Pataki Commission can only justify this giveaway by totally ignoring research by the State's tax policy experts who, in the Department of Taxation and Finance's recent report on the estate tax, concluded that «Migration studies regarding the impact of taxes such as the estate tax have shown that taxes generally are not a major factor in the decision of where to live or retire.»

And lets be honest, there has to be a major motivating factor to get us out to the polls as opposed to doing whatever other activity we undoubtedly had planned on election day.

A major study conducted on twins shows that environmental factors may be at least as important as genes in causing autism.

There's been some dispute over whether the pesticides are a major contributor to pollinator decline, with some farmers and pesticide manufacturers arguing that factors such as habitat loss and parasite infection have a bigger impact on bee populations.

Critics also claim that factors such as anxiety, boredom, weariness or ill - health can lead people to give different answers on different occasions, but in fact this is not a major weakness of psychological tests.

The effects of PTSD on heart disease remained strong even after researchers accounted for lifestyle factors such as smoking, physical activity level, and drinking; and major depression and other psychiatric diagnoses.

As an undergraduate biology major at Johns Hopkins University in Baltimore, Maryland, Niyogi focused on molecular and cell biology and thought about immunology or transcription factors as a potential field of studAs an undergraduate biology major at Johns Hopkins University in Baltimore, Maryland, Niyogi focused on molecular and cell biology and thought about immunology or transcription factors as a potential field of studas a potential field of study.

Although some of these factors appear to have a demonstrable effect on prevalence or course of macular degeneration (green leafy vegetables are good, cigarettes are bad), none has emerged as a likely major cause of it.

Steven E. Gelda, MD, focuses his clinical interest and expertise on ways to help stabilize psychiatrically hospitalized patients who enter the hospital in crisis due to environmental and interpersonal factors as well as those experiencing an episode of major mental illness.

The editors of JLR will pay close attention to the Spotlight Talks, as the journal is just wrapping up an eight - review series on the major risk factor for Alzheimer's disease, apolipoprotein E, and it's time to get inspired for the next one.

The Institute of Epidemiology II (EPI II) focuses on the assessment of environmental and lifestyle risk factors which jointly affect major chronic diseases such as diabetes, heart disease and mental health.

Components of the major metazoan developmental signalling pathways, as well as classes of developmental transcription factors, are mostly present in Amphimedon and absent from Monosiga and other non-metazoan genomes13, 14,16,27,29, suggesting that ontogenetic development, including primary germ cell formation (Supplementary Note 8.4), originated on the metazoan stem3, 11,12.

We propose that the discrepancies between the adult ASD and childhood ASD findings with respect to whole - brain functional connectivity may be reconciled by considering critical developmental factors such as the onset of puberty, which signals the beginning of adolescence and has a major impact on brain structure and function.

ApoE as a major causative factor and therapeutic target in Alzheimer's disease and other neurodegenerative disorders; small - molecule structure correctors to convert apoE4 to apoE3 and reverse the detrimental effects of apoE4 on mitochondria and the cytoskeleton; small - molecule protease inhibitors to block the formation of toxic fragments of apoE4; Plasma lipoprotein metabolism regulation involving apoE and apoB; cholesterol homeostasis modulation by lipoprotein receptors controlling lipoprotein clearance by the liver; Plasma HDL cholesterol (HDL - C) metabolism in the progression of atherosclerosis; the genetic epidemiology of the metabolic syndrome and low HDL - C levels established by the Turkish Heart Study.

The researchers concluded their study by noting that estimated fitness level — in consideration with other risk factors such as smoking status, alcohol consumption, and other health conditions — could have a major impact on identifying people at risk for future cardiovascular disease.

This has a negative impact on health, as studies show that low aerobic capacity is a major risk factor for premature death.

The delicate balance between the human microbiome and the development of psychopathologies is particularly interesting given the ease with which the microbiome can be altered by external factors, such as diet, 23 exposure to antimicrobials24, 25 or disrupted sleep patterns.26 For example, a link between antibiotic exposure and altered brain function is well evidenced by the psychiatric side - effects of antibiotics, which range from anxiety and panic to major depression, psychosis and delirium.1 A recent large population study reported that treatment with a single antibiotic course was associated with an increased risk for depression and anxiety, rising with multiple exposures.27 Bercik et al. 28 showed that oral administration of non-absorbable antimicrobials transiently altered the composition of the gut microbiota in adult mice and increased exploratory behaviour and hippocampal expression of brain - derived neurotrophic factor (BDNF), while intraperitoneal administration had no effect on behaviour.

That innovation continues on today as teachers blend styles like yin and vinyasa, as well as bringing in other practices into yoga, like Sculpt, which includes a major fitness factor.»

Shortened psoas major - this will often appear as rib thrusting when lying down on your back with the legs out straight (this was the most noticeable factor amongst the three aforementioned men with DR) and means that even just lying flat on your back, doing nothing -LRB-!)

Stress is known to have damaging effects on health and is widely recognized as a major risk factor in the development of heart disease and in heart disease -LSB-...]

Director of successful films about Indian retirement hotel says another film not on the horizon, citing age of principal cast as major factor

My own research (Burns, 2013) on online learning in Indonesia suggests that, as in a face - to - face classroom, the presence of a caring and knowledgeable online instructor is a major retention factor for teachers taking an online course.

As they put it, «[their] experts did an extensive study of all major LMS solutions currently available on the market and after analyzing their features, pricing plans, support quality, integrations, mobile support capabilities and other factors we know are important to users we found TalentLMS to be the best option available.»

That could have another major impact on colleges and universities, 800 of which have agreed to use the tests as at least one factor in deciding which students can bypass those exasperating and costly remedial courses.

IMPACT was designed to control for variables like the class's income level and English - language proficiency, and scores teachers on two major factors: classroom skill, as determined by multiple evaluations, and results, based on students» improvement on standardized tests.

If the announcement is as impressive as suggested, it would mean that the leadership of Connecticut's teacher unions have finally moved 180 degrees from the position they held on January 25, 2012 when the CEA and AFT joined with the other members of Governor Malloy's Performance Evaluation Advisory Council (PEAC) to approve the so - called «teacher evaluation framework» that inappropriately and unfairly mandates that student's standardized test scores be a major factor in the teacher evaluation process.

On Friday, The New York Times ran a story called «Higher Education in Illinois Is Dying» and cited rising pension costs as a major factor in the state's budget woes.

Hyundai was savvy enough to place a big emphasis on styling, as looks tend to be a major deciding factor for customers in this space.