In the absence of the Aβ challenge, tau reduction had no effect
on axonal transport.
Not exact matches
Work in several laboratories has shown that the retrograde
axonal transport of NGF follows its interaction with specific receptor sites
on the nerve terminals of the newly established fibers.
We study the influence of the Maillard reaction (leading to advanced glycation endproducts, AGEs)
on the function of specific proteins which are involved in the
axonal transport.
AGEs impair this
axonal transport and alpha adrenergic blockers (acting
on cell «stress receptors») can exert a protection of this phenomenon.Thus, will look
on the molecular mechanisms of this process (crosslinking of motor proteins in
axonal transport, energy depletion etc.) by analyzing the colocalization of fluorescence staining of (motor --RRB- proteins and tagged AGE - molecules and by methods of molecular biology.
Scaling great walls When they both started at Penn, Lee had a project
on the effects of nerve growth factor
on PC12 cells, and Trojanowski was studying
axonal transport and endocytosis.