L - carnitine also exerts positive effect
on blood lipids by lowering cholesterol LDL, total cholesterol and triglycerides (another bad fat which contributes to heart attacks and strokes) while raising good HDL - cholesterol.
Not exact matches
A new strategy — an injectable antibody — for lowering
blood lipids and thereby potentially preventing coronary artery disease and other conditions caused
by the build - up of fats, cholesterol, and other substances
on the artery walls, is supported
by findings from two new studies from researchers in the Perelman School of Medicine at the University of Pennsylvania.
Even that modest reduction in fat intake
by the dieters may have been fudged:
blood cholesterol and
lipid levels between the low - fat diet and control groups were nearly identical, suggesting that they were dining
on similar foods.
The researchers went
on to demonstrate that SHP - 1 is reduced in mouse vascular smooth muscle cells primarily
by the high levels of
lipids in the
blood associated with diabetes and related conditions, rather than the high levels of glucose also present in those conditions.
«Deficient neuron - microglia signaling results in impaired functional brain connectivity and social behavior» Y. Zhan, R.C. Paolicelli, F. Sforazzini, L. Weinhard, G. Bolasco, F. Pagani, A. L. Vyssotski, A. Bifone, A. Gozzi, D. Ragozzino, C.T. Gross Nature Neuroscience 17 (3), 400-4006 (2014) «USPIO - loaded Red
Blood Cells as a biomimetic MR contrast agent: a relaxometric study» A. Boni, D. Ceratti, A. Antonelli, C. Sfara, M. Magnani, E. Manuali, S. Salamida, A. Gozzi, and A. Bifone Contrast Media and Molecular Imaging 9, 229 - 236 (2014) «Distributed BOLD and CBV - weighted resting - state networks in the mouse brain» F. Sforazzini, A.J. Schwarz, A. Galbusera, A. Bifone, and A. Gozzi NeuroImage 87, 403 - 415 (2014) «Antimicrobial peptides design
by evolutionary multiobject optimization» G. Maccari, M. Di Luca, R. Nifosì, F. Caldarelli, G. Signore, C. Boccardi, and A. Bifone PloS Computational Biology 9 (9): e1003212 (2013) «Differential effect of orexin - 1 and crf - 1 antagonism
on stress circuits: a fMRI study in the rat with the pharmacological stressor yohimbine» A. Gozzi, S: Lepore, E: Merlo Pich, and A. Bifone Neuropsychopharmacology 38 (11): 2120 - 2130 (2013) «Water dispersal and functionalization of hydrophobic iron oxide nanoparticles with
lipid - modified poly (amidoamine) dendrimers» A. Boni, L. Albertazzi, C. Innocenti, M. Gemmi, and A. Bifone.
Kronenwett et al. «Oligodeoxyribonucleotide Uptake in Primary Human Hematopoietic Cells Is Enhanced
by Cationic
Lipids and Depends
on the Hematopoietic Cell Subset»,
Blood, 91 (3): 852 - 862, 1998.
Fasting
blood samples were processed
on the same day for serum
lipids, plasma glucose concentrations, white
blood cell (WBC) count, and fibrinogen
by the Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, Australia.
This paper, Effect of hypothalamic - pituitary - adrenal axis alterations
on glucose and
lipid metabolism in diabetic rats, reports that astragalus may improve HPA axis functioning and aid in the treatment of diabetes
by lowering
blood sugar and high levels of corticosterone (the rat version of cortisol).
Another important advantage to MCT consumption, is that KBs can be generated without the need to consume hard - to - follow, classical ketogenic diets containing very high amounts of fats (70 - 90 %
by weight), which may have adverse effects
on blood lipids and digestion.
A study in the journal Circulation found people with abnormally high level of
lipids, such as cholesterol, in their
blood were able to significantly reduce their risk factors for coronary heart disease
by snacking
on whole almonds (those who snacked
on whole - wheat muffins received no such benefit).6
The therapeutic dotential of dietary precursor modulation
by a fish - oil - supplemented diet (n - 3 fatty acids), such as eicosapentaenoic acid (C20: 5,n - 3) and docosahexaenoic acid (C22: 6,n - 3) in the therapy of ulcerative colitis has been shown to result in a 35 % to 50 % decrease in neutrophil production of LTB4.28 Significant improvement in symptoms and histologic appearance of the rectal mucosa has been observed in several small series of patients with Crohn's disease and ulcerative colitis given fish oil at 3 to 4 g daily for 2 to 6 months in uncontrolled studies.29 However, a larger, randomized, double - blind trial comprising 96 patients with ulcerative colitis failed to reveal any benefit in remission maintenance or treatment of relapse
on 4.5 g of eicosapentaenoic acid daily, despite a significant reduction in LTB4 synthesis
by blood peripheral polymorphonuclear cells.30 It should be emphasized, however, that the anti-inflammatory actions of the fish oils, in addition to inhibition of LTB4, include suppression of IL - 1 and platelet activating factor synthesis and scavenging of free oxygen radicals.30 The impact of increased
lipid peroxidation after fish oil supplementation should be considered when altering the n - 6: n - 3 fatty acid ratio.31 Antioxidant supplementation may be able to counteract the potentially adverse effects of n - 3 fatty acids.