To expedite research
on brain disorders, the National Institutes of Health is shifting from a limited funding role to coordinating a Web - based resource for sharing post-mortem brain tissue.
Lipkin and Hornig have worked together for 21 years trying to tease out the impact of infection and immunity
on brain disorders such as autism and schizophrenia, and more recently CFS / ME.
Not exact matches
One biotech firm, Ossianix, is already hard at work developing a VNAR - based drug - delivery system, in collaboration with the global pharmaceutical company Lundbeck, which focuses
on drugs for
brain disorders.
You sound as uneducated as a person
on another blog that claimed that being gay is the same as having ADHD or bipolar
disorder: a chemical imbalance in the
brain.
Impaired digestive health leads to serious health problems like: autoimmunity asthma allergies mood issues cardiovascular disease
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Early life stress, such as an extreme lack of parental affection, has lasting effects
on a gene important to normal
brain processes and is also tied to mental
disorders.
«BPA - free» means that the bottle was manufactured without the industrial chemical called bisphenol A. BPA has been connected to negative health effects
on the
brain, heart diseases, reproductive
disorders and impotence for men.
They also found that some of the athletes, none of whom suffered diagnosed concussions, didn't do as well as predicted
on tests of learning and memory at the end of the season, although the study did not find «large - scale, systemic differences» in the
brain scan measures, which the authors found «somewhat reassuring» and consistent with the fact that millions of athletes play contact sports for many years without developing progressive neurodegenerative
disorders.
Dr. Perry's research includes: the effects of prenatal drug exposure
on brain development, the neurobiology of human neuropsychiatric
disorders, the neurophysiology of traumatic life events, and long - term cognitive, behavioral, emotional, social and physiological effects of neglect and trauma in children, adolescents and adults.
He had been
on medical leave from the chamber since early this year after he was diagnosed with Creutzfeldt - Jakob disease, a rare, degenerative and fatal
brain disorder.
«Altering Huntington's patients» skin cells into
brain cells sheds light
on disease: Reprogrammed
brain cells exhibit «symptoms» of fatal
disorder.»
Significant advances emerging from neuroscience and computer technology have long been a goal of the U.S. military in its quest to find better ways to use
brain - related technology to boost national security, and more recently, address debilitative injuries resulting from improvised explosive devices and posttraumatic stress
disorder, according to two experts
on neuroscience and ethics.
In the first study to assess the relationship between structural and functional MRI data in bipolar
disorder, Dr. Shantanu Joshi and his colleagues at the University of California, Los Angeles focused
on brain regions that play a role in mood dysregulation in the
disorder.
Spurred
on by the finding, Johnson and Wemmie conducted an extensive search of the scientific literature
on bipolar
disorder and began to find pieces of evidence that suggested that the cerebellum may function abnormally in bipolar
disorder and that lithium might potentially target the cerebellum and alter glucose levels in this
brain region.
In the end all of the researchers interviewed by Scientific American emphasized significance only goes so far in making a case for IAD as a true
disorder with discrete effects
on the
brain.
They base their argument
on mounting evidence showing that the
brains of people who have committed suicide have striking similarities, quite distinct from what is seen in the
brains of people who have similar mood
disorders but who died of natural causes.
Emory medical school neurologist and depression researcher Helen Mayberg explains that her work
on depression strives to describe the same overarching concepts that Freud invoked, including links between
brain circuits and
disordered moods.
- Collaborative Research in Computational Neuroscience Supports collaborations among computer scientists, engineers, mathematicians, statisticians, theoreticians and experimental neuroscientists, which are imperative to advance our understanding of the nervous system and mechanisms underlying
brain disorders and have a significant impact
on the theory and design of engineered systems.
Scientists used CRISPR - Cas9 to shed light
on why people with 15q13.3 microdeletion syndrome — a rare human genetic
disorder — are more likely to develop
brain disorders like autism spectrum
disorder, epilepsy and schizophrenia (Karun K. Singh, abstract 103.05, see attached summary).
A groundbreaking therapy, relying
on mindfulness meditation to treat obsessive compulsive
disorder, suggests even adult
brains have neuroplasticity.
For example, knowing the precise
brain activity involved could shed light
on disorders in which body awareness is disrupted, such as schizophrenia, and help with the development of prosthetic limbs that are more easily incorporated into body image.
Stem cells have long been heralded as a potential treatment for a range of
brain ailments, but research has so far focused
on movement
disorders such as Parkinson's disease.
Last month, researchers led by Beth Stevens of Boston Children's Hospital reported that a process in which microglia prune excess synapses in the
brain during early life can turn
on inappropriately later
on, possibly triggering Alzheimer's or other
disorders marked by damage to connections between
brain cells.
The researchers caution that their findings, described online
on May 4 in npj Schizophrenia — a new publication from Nature Publishing Group — do not establish a cause - and - effect relationship between mental illness and yeast infections but may support a more detailed examination into the role of lifestyle, immune system weaknesses and gut -
brain connections as contributing factors to the risk of psychiatric
disorders and memory impairment.
Pandey explained that early life exposure to alcohol can have not only long - lasting effects
on brain chemistry but also induce a predisposition to psychiatric problems such as alcohol abuse and anxiety
disorders.
The discovery, which shows that the
brain has a far greater ability to adapt and respond to changes than previously believed, could have significant implications
on epilepsy, movement
disorders, and psychiatric and neurodegenerative disease.
Neuroscientists are now using optogenetics to map
brain activity and test the effectiveness of an
on / off switch in treating
disorders.
As a whole, the findings suggest the proteins act
on the gut —
brain axis — the collection of two - way nerve and chemical pathways that communicate between the digestive tract and the
brain — and that GDF15 might be a clinical target for metabolic
disorders.
The
brain -
on - a-chip could be useful for studying any number of neurological and psychiatric diseases, including drug addiction, post traumatic stress
disorder, and traumatic
brain injury.
The projects vary slightly in their aims — the US
BRAIN initiative will start by cataloguing the types of cells in the brain and how they wire together, while the China Brain Science Project is focused on developmental, psychiatric and neurodegenerative disor
BRAIN initiative will start by cataloguing the types of cells in the brain and how they wire together, while the China Brain Science Project is focused on developmental, psychiatric and neurodegenerative disor
BRAIN initiative will start by cataloguing the types of cells in the
brain and how they wire together, while the China Brain Science Project is focused on developmental, psychiatric and neurodegenerative disor
brain and how they wire together, while the China Brain Science Project is focused on developmental, psychiatric and neurodegenerative disor
brain and how they wire together, while the China
Brain Science Project is focused on developmental, psychiatric and neurodegenerative disor
Brain Science Project is focused on developmental, psychiatric and neurodegenerative disor
Brain Science Project is focused
on developmental, psychiatric and neurodegenerative
disorders.
And its Defense Sciences Office (DSO) has aligned with President Barack Obama's
Brain Research through Advancing Innovative Neurotechnologies Initiative, calling for grant applications on projects to design therapeutic devices for neurological disorders and to repair brain damage in military service mem
Brain Research through Advancing Innovative Neurotechnologies Initiative, calling for grant applications
on projects to design therapeutic devices for neurological
disorders and to repair
brain damage in military service mem
brain damage in military service members.
«The imaging technique could shed light
on the immune dysfunction that underpins a broad range of neuroinflammatory diseases, such as Alzheimer's disease, depression, post-traumatic stress
disorder and addiction,» said Christine Sandiego, PhD, lead author of the study and a researcher from the department of psychiatry at the Yale School of Medicine in New Haven, Conn. «This is the first human study that accurately measures this immune response in the
brain.
Voss now plans to test whether this method works
on individuals who have
disorders in which the memory association network is weak, such as Alzheimer's disease, traumatic
brain injury and schizophrenia.
It is exactly during puberty that substances like drugs of abuse — alcohol, cannabis, etc. — may induce the most destructive and also persistent effects
on the still developing
brain, which may in some cases even result in neuropsychiatric
disorders, such as schizophrenia or addictive
disorders.
Clinically, this growing body of knowledge
on the multisensory
brain is opening novel avenues for addressing sensory and learning
disorders.
Scientists hope the hundreds of thousands of images they produce will help them zero in
on brain wiring and anatomical differences in children that develop
disorders such as autism.
«Antiretroviral treatment only partially penetrates the blood
brain barrier, which means that even if a patient is free of HIV systemically, the virus is still able to rage
on in the
brain, causing cognitive
disorders and mental decline,» Dr. Dadachova said.
The study focused
on the serotonin transporter, a molecule that regulates the amount of serotonin signaling between
brain cells and is a major target for treatment of depression and mood
disorders.
The discovery of connectivity deficits in a specific region of the
brain like the SLF provides an important starting point for more research
on people with IED, as well as those with borderline personality
disorder, who share similar social and emotional problems and appear to have the same abnormality in the SLF.
For example, the American Psychiatric Association, which publishes the DSM,
on its website describes schizophrenia as «a chronic
brain disorder,» and academic journals describe it as a «debilitating neurological
disorder,» a «devastating, highly heritable
brain disorder,» or a «
brain disorder with predominantly genetic risk factors.»
Mitochondrial diseases include Leigh syndrome, a progressive and fatal
disorder characterized by lesions
on the
brain that may lead to heart, kidney, vision and breathing complications, and Alpers Disease, a neurologic illness that causes seizures, dementia, spasticity, blindness, liver dysfunction and cerebral degeneration.
«It suggests that lithium could have its well - known therapeutic effect
on patients with bipolar
disorder by changing the stability of spines in the
brain.»
The cover story
on novel ways of treating
disorders of the
brain (9 April, p 35) stated that «until recently...
The detailed new map of early
brain growth in healthy babies could shed light
on what goes wrong in neurodevelopmental
disorders such as autism, BBC reports.
A genetic variation linked to schizophrenia, bipolar
disorder and severe depression wreaks havoc
on connections among neurons in the developing
brain, a team of researchers reports.
The group» finding that the impaired intracellular protein trafficking leads to neuropsychiatric
disorders - related abnormal higher
brain functions has high impact
on the fields of psychiatry, basic medical sciences, and pharmaceutical sciences.
«Blame it
on the astrocytes: does
brain's most abundant cell type have role in neurological
disorders?.»
«Studies
on post-traumatic stress
disorder have shown traumatic events can have profound influences
on receptors in this region of the
brain, perhaps rendering soldiers more prone to addiction.
Understanding how common
brain circuits for decision - making contribute to seemingly unrelated
disorders will allow researchers to focus
on core disturbances and leverage treatment advances across different
disorders.»
The researchers are now examining changes in the
brains of individuals who go
on to develop psychotic
disorders, as well as potential environmental and genetic risk factors that may predispose individuals to poor cognition.