Sentences with phrase «on breast cancer tissue»

Fluorescence in situ hybridization, or FISH, is a screening test that can be performed on breast cancer tissue removed during a biopsy.

Not exact matches

Their research, published in PLOS ONE, focused on one particular gene — TRIM29 — selected from a pool of 100 genes with regulatory patterns specific to normal breast tissue, to prove the link between breast - specific genes and the pathology of cancer.

«Our findings highlight the potential value for a randomized controlled trial of aspirin as an agent in early detection of breast cancer, particularly for women with naturally dense tissues who may be at an increased risk for certain cancers,» said Despina Kontos, PhD, assistant professor of Radiology, and co-author on the study.

In tests on human breast cancer cells and in special immunodeficient mice with tissue grafts, the scientists found that both agents interfered with genes involved with breast cancer cell growth, resulting in more cancer cells.

The authors believe theirs is the first study to show that mouse mammary gland tissues are sensitive to a mixture of 23 commonly used UOG chemicals, with dose - specific effects on tissue morphology, cell proliferation and induction of intraductal hyperplasias, an overgrowth of cells considered a marker for future breast cancer risk.

Since diet can influence insulin activation, the researchers wondered whether diet could impact breast cancer prognosis based on expression of the IGF1 receptor in the primary breast tumor tissue.

Women with higher breast density — detected on mammograms — have more compacted breast tissue and are more likely to develop breast cancer, but until now the reasons for this have been unclear.Manchester scientists, funded by leading UK research organisation Breakthrough Breast Cancer, worked with IBM researchers and academics in the USA and Cyprus to uncover the biological mechanisms atbreast density — detected on mammograms — have more compacted breast tissue and are more likely to develop breast cancer, but until now the reasons for this have been unclear.Manchester scientists, funded by leading UK research organisation Breakthrough Breast Cancer, worked with IBM researchers and academics in the USA and Cyprus to uncover the biological mechanisms atbreast tissue and are more likely to develop breast cancer, but until now the reasons for this have been unclear.Manchester scientists, funded by leading UK research organisation Breakthrough Breast Cancer, worked with IBM researchers and academics in the USA and Cyprus to uncover the biological mechanisms atbreast cancer, but until now the reasons for this have been unclear.Manchester scientists, funded by leading UK research organisation Breakthrough Breast Cancer, worked with IBM researchers and academics in the USA and Cyprus to uncover the biological mechanisms atcancer, but until now the reasons for this have been unclear.Manchester scientists, funded by leading UK research organisation Breakthrough Breast Cancer, worked with IBM researchers and academics in the USA and Cyprus to uncover the biological mechanisms atBreast Cancer, worked with IBM researchers and academics in the USA and Cyprus to uncover the biological mechanisms atCancer, worked with IBM researchers and academics in the USA and Cyprus to uncover the biological mechanisms at play.

The news wasn't all bad: When Fischbach's team put obese mice on a diet, their mammary fat tissue had fewer myofibroblasts, suggesting losing weight could make a woman's fat tissue structure more normal and lower her breast cancer risk.

«Computer accurately identifies and delineates breast cancers on digital tissue slides: Deep - learning network possible step toward automating biopsy slide analysis.»

Cosmetic breast implants have become increasingly popular, but some studies have suggested that implants can make it more difficult to detect breast cancer at an early stage because they create shadows on mammograms that can obscure some breast tissue.

Interestingly, the team found that radiologists could do better than chance in discriminating breast cancer cases from normal tissue, even when the images of abnormal breast tissue did not directly capture a cancerous lesion or when those images were taken from the contralateral breast (the breast on the other side of the body) of a woman with breast cancer.

On Capitol Hill last week, Weinberg, an expert in the molecular biology of cancer, pointed out to the Congressional Biomedical Research Caucus that the major advances in understanding human cancer genetics had come, not from studying breast tissue, but from studying cow warts, worm vulvas, fruitfly retinas, and a chicken virus.

Injections of iPSC - EPCs did not however have significant effect on tumor growth or on overall survival, but transducing cells with a baculovirus expressing CD40L, a member of the TNF gene family which can induce apoptosis [6, 7], and injection into the breast cancer lung metastasis, increased levels of pro-apoptotic cytokines in lung tissues, indicating the induction of apoptosis by CD40L carried by the EPCs (See figure).

Understanding what regulates CSCs in specific tissues, such as for breast cancer, will inform on drug regimens and may allow us to predict cancer outcomes.

Here, we elaborate on how these findings pertain to cancer cells dispersed in the tumor - adjacent stroma of breast cancer tissues, and how BH3 - mimetics may provide a therapeutic strategy to eliminate cancer cell populations that have passed through an EMT.

I had a hunch based on this work that microRNA expression would be different in breast cancer stem cells than in more differentiated tumor cells or normal tissue and that it would change as the stem cells differentiated to form a tumor.

Our bioinformatics analysis, based on multiple independent large - size cohorts shows that MELK is strongly overexpessed in BBC / TNBC, not only compared to normal breast tissues, but also compared to luminal or ER / PR + breast cancer.

For severe cases, doctors sometimes prescribe Danazol, a steroid derivative that decreases levels of the reproductive hormones FSH and LH, or tamoxifen, a breast - cancer drug that helps relieve breast pain by blocking estrogen receptors, thus preventing estrogens effect on breast tissue.

The cancer promoting effects of estrogen on breast tissue are restricted by lignan compounds which bind to estrogen receptors.

Your treatment will depend on where your cancer started, whether it has invaded other breast tissue or spread to other parts of your body, and whether hormones like estrogen or progesterone fuel its growth, among other factors.

(55) A 2007 animal study with primates treated with either bioidentical progesterone or a progestin (Provera ™) showed that the progestin drug (Provera ™) worsens breast cancer biomarkers, while the bioidentical progesterone provides a beneficial effect on breast tissue and reduces cancer markers.

Really, it depends on a number of factors not the least of which is that mammography is looking at shadows, and if you have dense breasts, if you have a lot of tissue in your breasts, it can easily hide a cancer.

Studies have shown that women on a high - fiber diet have lower levels of circulating estrogen, meaning less estrogen stimulation of breast tissue, for example, which reduces the risk of breast cancer.

Most breast cancers can be seen on a mammogram even in women who have dense breast tissue, so it's still important to get regular mammograms.

A tissue culture study of human breast - cancer cells found that epigallocatechin gallate, or EGCG, an active compound in green tea, protects against some forms of breast cancer by regulating estrogen receptors on breast cells and inhibiting growth and reproduction of estrogen - dependant breast - cancer cells.

There's a lot of buzz on the blogosphere that aluminum causes breast cancer because it's found in breast tissues, but correlation does not mean causation.

Dr. Kelly is one of the country's leading authorities on ultrasound to detect cancers on women with dense breast tissue and / or implants.

At diagnosis, inflammatory breast cancer is either stage III or IV disease, depending on whether cancer cells have spread only to nearby lymph nodes or to other tissues as well.

Tell One., a cancer organization focused on dense breast tissue awareness.