Sentences with phrase «on cancer cell»

Part of the talk discussed results of experiments which showed the inhibiting effects of diet (plant substances) on cancer cell growth.

In an attempt to «determine the underlying mechanisms for these anticancer effects», cell apoptosis was again to be examined when the blood of a group eating a similar diet was dripped on a cancer cell line.

did they pour those veggies, pureed, on a cancer cell?

Historically, a potential therapeutic compound would be tested on cancer cell lines to validate the functional efficacy of the compound.

Researchers can also find information on the cancer cell lines that are most suitable for their experiments.

We target tumours by exploring how the proteins found on the cancer cell surface can be utilised to inhibit growth or kill tumours.

Lycopene's effects on cancer cell functions within monolayer and spheroid cultures.

«Once we identify candidate proteins, we can manipulate and test them for their effect on cancer cell metastasis,» says Klemke.

Triple negative breast cancers are those that do not have estrogen or progesterone receptors, and do not have an excess of the HER2 protein on the cancer cell surfaces.

In the new paper, researchers led by Dr. Torres showed that LPA keeps T cells inactivated even after they have «seen» a target, or antigen, on a cancer cell that would normally trigger an immune response.

On a cancer cell, long glycopolymers result in an expanded membrane - extracellular matrix gap, clustering of integrins and membrane bending.

The researchers found that long glycoprotein chains on a cancer cell's surface cause the cell membrane to push away from its environment and bend inward.

Co-senior author on the Cancer Cell study, Dr. Matthew Wilkerson, associate professor and Bioinformatics Director of The American Genome Center and the Collaborative Health Initiative Research Program at the Uniformed Services University.

The ManCou multicolored fluorescent probe glows different colors and different intensities depending on a cancer cell's type and malignancy.

«We developed a technique that targets lipid rafts on cancer cell membranes,» says Professor Ye Zhang from OIST's Bioinspired Soft Matter Unit, who led the research.

After completing her graduate studies in 2006, she joined the laboratory of Dr. Craig B. Thompson at the University of Pennsylvania for postdoctoral work focusing on cancer cell metabolism.

«Over the years, we've developed the theory of «sequential cytotoxicity,» which simply means you give an initial attack on the cancer cell and then you give a second chemical attack,» Dimmock said.

In this study, the SIgN team discovered for the first time that the integrity of p53 affects the production of a special cell surface protein called Major Histocompatibility Complex (MHC) class I. MHC class I molecules on the cancer cell surface serve as targets for the immune system.

did they pour those veggies, pureed, on a cancer cell?

The medicines, which help unleash the immune system on cancer cells, were tested in patients with advanced lung cancer.

It's a type of cancer immunotherapy, which harnesses the body's immune system to take on cancer cells.

Investigators have repeatedly touted the drug as a potential lynchpin in immuno - oncology, focusing on an enzyme that suppresses the immune cells Opdivo and a whole new class of PD - 1 / L1 checkpoints are designed to unleash in an attack on cancer cells.

He also investigates the effects of 2HG inhibitors on cancer cells.

The same seems to be true of the gene switches that turn on cancer cells.

The removal of these components might be expected to unleash an assault by the immune system on cancer cells left after surgery.

In the early 1990s, in vitro tests on cancer cells by Lane and his colleagues hinted that some compounds could restore mutant p53's normal function.

Erbitux binds to and inhibits a growth - promoting protein on cancer cells.

Lab testing showed that the plant - made virus particles, which naturally bind to receptors on cancer cells, were taken in by human breast cancer cells.

This mutation is on a particular receptor, or docking site, on the cancer cells that is crucial to the cell's growth and survival.

Among patients who have this type of lung cancer, nearly one in three will carry a particular genetic mutation on their cancer cells.

Once Herceptin binds to HER2, however, DM1 is released and acts on cancer cells in the vicinity.

Similar strategies already in use select immune cells that recognize any cancer antigen, but Swanton's group would select those that are primed to recognize the trunk antigens that occur on all cancer cells.

The targeted viruses «have the potential to add a new tool to our arsenal,» he says, because they home in on cancer cells more aggressively.

To date, it was assumed that chloroquine increases the sensitivity of cancer cells to chemotherapy by means of a direct effect on the cancer cells.

Mouse fibroblasts, however, had no effect on the cancer cells.

«We have shown that our molecule works on cancer cells in the lab, but the next step is to see if it works on real tumors in animals.

This ability to isolate, culture and grow the cancer cells will allow researchers to zero in on the cancer cells that matter to the health of the patient.

It also focuses more narrowly on cancer cells, so that far fewer healthy cells are killed,» she says.

About 20 percent of breast cancer patients have overexpressed growth receptors, known as Her2 + receptors, on the cancer cells, which cause uncontrolled tumor growth.

«The big surprise,» Discher said, «is that injected macrophages circulate all around the body but accumulate only within the tumors where they engorge on cancer cells.»

Three new studies suggest ways to home in on cancer cells during treatment, leaving surrounding healthy tissue unharmed.

The more it's expressed only on cancer cells, the more targeted the therapy becomes,» says Colin Weekes, MD, PhD, CU Cancer Center investigator and assistant professor in the Division of Oncology at the CU School of Medicine.

The team demonstrated the efficacy of the system by analyzing the metabolic conversion in liver cells of Tegafur, a chemotherapeutic pro-drug, into the toxic metabolite 5 - fluorouracil and its subsequent effect on cancer cells.

FY26 has been shown to be more selective between normal cells and cancer cells than cisplatin — having a greater effect on cancer cells than on healthy ones.

The sponge is implanted under the skin, and is designed to recruit and reprogram a patient's own immune cells «on site,» instructing them to travel through the body, home in on cancer cells, then kill them.

«The LINK - A dependent HIF1 signalizing cascade and the consequent effects on cancer cells implicate LINK - A and LINK - A interacting kinases and receptors as promising therapeutic targets for TNBC.»

A new study by a Cornell University researcher found this coating is especially thick and pronounced on cancer cells and is a crucial determinant of the cell's survival.

Antibody that blocks a «do not eat» flag on cancer cells turns the immune system against all tumor types

Further, when TILs have been used for such purposes, the proportion of what Harari calls the «juiciest» T cells — those recognizing mutations on cancer cells — tends to decline significantly when the cells are expanded in culture.

The demands of rapid cell division put a strain on cancer cells, and the approach works by tipping cell stress over the edge.