Sentences with phrase «on cell and tissue»

«It provides up - to - date insights into recent regulatory developments, challenges to international harmonization, new perspectives on cell and tissue banking as well as critical reflections on the marketing of stem cell therapies, among many other themes.»

Wanting to pursue more experimental research, he headed to the Massachusetts Institute of Technology for a postdoc to join a lab of engineers who focused on cell and tissue culture experiments.

Oxidation — Stress on the cells and tissues cased by oxidation is one of the leading causes of aging.

When applied to humans and other animals, cytokinins have potent anti-aging effects on cells and tissues.

The following beneficial effects of K laser [Class IV laser] therapy on cells and tissues have been demonstrated in clinical trials and studies of laser therapy technology:

BioActive is the use of biologically active compounds in the product and is also a term used in veterinary research, referring to the compounds that have an effect on cells and tissues — examples include fatty acids, flavonoids, choline, prebiotics and polyphenols.

Not exact matches

In the course of it, you lose hundreds of millions of muscle cells that won't be replaced, and instead less flexible scar tissue forms on the heart, which can lead to patients needing a heart transplant.

ReInnervate, a start - up in Durham, England, is developing a tiny, three - dimensional plastic scaffolding on which human cells can be grown into artificial tissue, and perhaps eventually into replacements for organs.

Drawing on Toronto's leading stem cell and tissue engineering expertise, one group will focus on new models for repairing damaged hearts.

Whilst acknowledging that many questions remain unanswered in the debate between those who would advocate the use of stem cells taken from human embryos, and those experimenting on stem cells drawn from tissues of the adult human body, there is a lengthy discussion of the moral status of the human embryo as being a crucial matter in this regard.

Thus, the rate of freezing for plant tissues is extremely important due to the effect of freezing rate on the size of ice crystals, cell hydration, and damage to cell walls (Rahman, 1999).

Most other lubricants, freshening gels, and massage oils on the market are hypo or hypertonic (too low or too high of a salt concentration compared with vaginal tissues), and cause water to be pushed into, or pulled out of the vaginal cells.

One such protein, EGF, was already high on the list of suspects due to its abundant presence in breast milk and its well - known role in promoting the growth and development of cells in various tissues.

They're harmless, but do keep an eye on the size and quantity of these spots, since having six or more that are larger than a quarter may be a sign of neurofibromatosis (a genetic disorder that causes abnormal cell growth of the nerve tissue).

Lab - grown tissues derived from patients» stem cells may also allow researchers to screen drugs and test their effectiveness on diseases like cancer.

The fields within biology are further divided based on the scale at which organisms are studied and the methods used to study them: biochemistry examines the fundamental chemistry of life; molecular biology studies the complex interactions of systems of biological molecules; cellular biology examines the basic building block of all life, the cell; physiology examines the physical and chemical functions of the tissues and organ systems of an organism; and ecology examines how various organisms interrelate.

To discover these targets, the team determined when and where each gene is turned on or off in the cells and tissues of H. contortus to reveal new insights into the worm's lifecycle.

On Thursday, the United Nations» member states will consider two resolutions: One resolution would ban all human cloning methods, including efforts to use cloned embryonic stem cells to try and generate healthy tissues, or to treat degenerative diseases such as Parkinson's.

Da Cruz and his team grew replacement RPE cells from human embryonic stem cells on a thin plastic scaffold, before transplanting the tissue into the back of each volunteer's eye.

This pilot research builds on an earlier study by Milovancev and collaborators that examined the ability of MRIs and CT angiograms to detect cancerous lesions related to FISS, and another study that looked at three methods for assessing margins for canine mast cell tumors and soft tissue sarcomas.

Now, the team has examined whether sepsis has the same impact on tissue resident memory T cells (TRM), which do not circulate but stick to the skin, lungs, and gut — where infections often enter the body.

Scientists are forced either to experiment on whole animals, which is expensive, raises ethical issues and may not predict effects in humans, or to perform tests on microscopic human cells found in tissue cultures, which have been altered to live forever and bear little relation to actual living, breathing people.

It can be done on tissue sections (fresh or fixed tissue), cell suspensions, and so on.

A detour on the road to regenerative medicine for people with muscular disorders is figuring out how to coax muscle stem cells to fuse together and form functioning skeletal muscle tissues.

As might be expected of an autoimmune disease, where the immune system turns on healthy tissue, all the genes play a role in controlling the growth and multiplication of cells in the immune system.

This drug (vedolizumab) blocks a specific adhesion molecule on the surface of the T - cell and thereby inhibits immune cells from binding themselves to receptors present in the intestine, preventing the T - cells from penetrating the blood vessels in the intestinal tissue.

«ENCODE is a living project and the maps that are generated are constantly updated and improved, with information being added on new types of cells and tissues or new complementary genome assays.

Many studies have shown that stiffness of the extracellular matrix, the fibrous network of collagen that surrounds cells, promotes cellular mobility; cells can get a better grip on stiffer surfaces and thus invade neighboring tissue.

Some of the leading non-animal tests are conducted on cell cultures, human and animal corneas from eye banks, corneal tissue cultures, and frozen corneas supplied by hospitals.

Experiments on Earth using microgravity have shown that stem cells — the master cells that produce all organ and tissue cell types — will grow faster, compared to conventionally grown cells.

In a study published in the journal Science, an international collaboration of investigators from Dana - Farber, Harvard Medical School, Boston Children's Hospital, and the University of Strasbourg uncovered a mechanism that allows key immune system cells to keep a steady rein on their more belligerent brother cells, thereby protecting normal, healthy tissue from assault.

Previous studies have found that brown fat can be coaxed into action by activating the β3 - adrenergic receptor, which is expressed on the surfaces of brown and white fat cells, as well as on cells of the urinary bladder and other tissues.

«Knowing how cells respond to mechanical cues in the living embryo and how they physically sculpt tissues and organs in the 3D space will transform the way we think about developmental processes,» said Otger Campàs, a professor in the Department of Mechanical Engineering at UCSB and senior author on the paper that reports this novel technique in Nature Methods.

When they examined mice genetically incapable of producing Helios, they found the animals beset by a T - cell and antibody attack on normal tissue.

These techniques include: human tissue created by reprogramming cells from people with the relevant disease (dubbed «patient in a dish»); «body on a chip» devices, where human tissue samples on a silicon chip are linked by a circulating blood substitute; many computer modelling approaches, such as virtual organs, virtual patients and virtual clinical trials; and microdosing studies, where tiny doses of drugs given to volunteers allow scientists to study their metabolism in humans, safely and with unsurpassed accuracy.

The «target» cells on the other side of the BeWo barrier to the nanoparticles were human fibroblast cells, found in skin and connective tissue.

Sen and his colleagues tested sucralose, a popular low - calorie sweetener, on stem cells — cells that could change into mature fat, muscle, cartilage or bone cells — taken from human fat tissue.

Scientists have focused for decades on the role of biochemical cues in embryonic development, Campàs said, because no techniques existed to measure the mechanical cues that cells are exposed to during the formation of tissues and organs.

Four weeks after the team switched on the enzyme, they found that tissue had regenerated in several organs, new brain cells were developing and the mice were living longer.

Matteo Boretto, the first author on this study, commented that «we were very excited to see that we could not only robustly grow and amplify endometrial tissue in a dish, but that the tiny structures were also able to reproduce normal responses of the endometrium to hormones: oestrogen makes the tissue thicken, progesterone then induces maturation including folding (see picture), and subsequent removal of both hormones mimics the cell shedding of the menstrual period.»

Building upon their earlier research on the biology of fat metabolism, Joslin scientists discovered that microRNAs - small RNA molecules that play important roles in regulation in many types of tissue — play a major role in the distribution and determination of fat cells and whole body metabolism.

Biotech's latest mantra is «proteomics,» as it focuses on how dynamic networks of human proteins control cells and tissues

Deleting telomere elongation capacity throughout the body would also be life - threatening, because it would mean that our regular proliferating cells (like those in the skin or the lining of the gut) would suddenly have iron limits on their ability to reproduce themselves and thus replenish tissue.

Get a cut on your finger and your skin can make new cells to heal the wound; lose your tail — if you are a particular kind of lizard — and tissue regeneration may produce a new one.

By monitoring stem cell differentiation on gels that mimic the stiffness and nanofibrous structure of biological tissue, researchers have identified the specific molecules that stem cells use when selecting bone and cartilage fates.

They took cells from those tissue samples and successfully grew them on a three - dimensional scaffold to produce new vocal cords.

Yonju Ha, a lead author of this article, said that further studies on this receptor and its role in white blood cell recruitment following tissue injury may aid in the development of new interventions for diseases associated with nerve injury, such as TON, stroke, diabetic retinopathy and glaucoma.

The same compound promotes the growth of tooth tissue called dentine — a protective material between the sensitive pulp inside a tooth and the enamel on its surface — so Cohen believes that the type of tissue formed partly depends on the neighbouring cells.

At its most basic, synthetic biology is about making DNA from scratch, on scales from individual molecules to cells, tissues and even entire organisms.

«To date, there has been no systematic means of assessing the fidelity of cellular engineering — to determine how closely cells made in a petri dish approximate natural tissues in the body,» says George Q. Daley, MD, PhD, Director of the Stem Cell Transplantation Program at Boston Children's and senior investigator on both studies.