Sentences with phrase «on cell behavior»

My laboratory also conducts fundamental research using genetics, biochemistry, cell biology and proteomics to define mechanisms of ECM assembly and turnover and their effects on cell behavior.

Biological Function of Ribosomal Protein L10 on Cell Behavior in Human Epithelial Ovarian Cancer Jimin Shi, Lingyun Zhang, Daibing Zhou, Jinguo Zhang, Qunbo Lin, Wencai Guan, Jihong Zhang, Weimin Ren, Guoxiong Xu J. Cancer 2018; 9 (4): 745 - 756.

«We're seeing that some of these factors have a major impact on cell behavior that is not possible to observe in conventional 2D cell cultures.»

Not exact matches

While we should hesitate to pass an anachronistic judgment on his behavior, we can at least restrain the celebrations of his fiancée, Maria von Wedemeyer, as his true love, the heroine for the perfect hero — celebrations that were inspired by the publication of their correspondence in Love Letters from Cell 92.

First seen as poisons, then as life - forms, then biological chemicals, viruses today are thought of as being in a gray area between living and nonliving: they can not replicate on their own but can do so in truly living cells and can also affect the behavior of their hosts profoundly.

I'm leaving my cell in the car and re-focusing on all that good ol' attachment - promoting behavior with which I was so engaged the first few months T was home with us.

While it may not be written in our conscious memories, experiencing birth remains in our very cells, and is certainly within our subconscious - influencing much of our behavior, reactions and perspectives later on in life.

It's important that your tween knows that his cell phone privileges mean he has to keep you in the loop on his behavior or the behavior of others.

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Joe W. Ramos, PhD, deputy director of the UH Cancer Center and collaborators focused on investigating how these oncogenes and related signals lead to dysregulation of normal processes within the cell and activate highly mobile and invasive cancer cell behavior.

Markram's model will electronically mirror the real brain's biological behaviors, imitating mathematically the interactions among individual neurons and the effects of neurotransmitters on those cells.

By manipulating chemical reactions, behaviors of cells can be mimicked resulting in chemical factories on the nanoscale controlled and not by physical touch but by magnets and light.

Next, Anderson and his colleagues used a set of genetic tools to identify exactly which neurons were responsible for the effect on aggression and to see if the gene that encodes for Tk also controls aggressive behavior by acting in that cell.

First seen as poisons, then as life - forms, then biological chemicals, viruses today are thought of as being in a gray area between living and nonliving: they can not replicate on their own but can do so in truly living cells and can also affect the behavior of their hosts profoundly.

«If cancer recurs, it may be because the therapy didn't hit key mature cells that take on stem cell - like behavior.

Mounted on a rat's head, the 1.5 - inch plastic and titanium instrument allows the animal to move freely and captures in real time how brain cells interact during everyday behaviors.

The «domestication syndrome» in mammals: A unified explanation based on neural crest cell behavior and genetics.

Wall was the senior and corresponding author on a paper, titled «Cell Rejuvenation and Social Behaviors Promoted by LPS Exchange in Myxobacteria» that was published in the May 18 online issue of the Proceedings of the National Academy of Sciences (PNAS).

But according to Michael McKeown, a developmental geneticist at the Salk Institute in La Jolla, California, fru's presence in nine small clusters of fly nerve cells — including several previously mapped by Hall as «courtship centers» — may begin to give researchers «a handle on how the neural circuits that generate complex behaviors are put together.»

These claims were based on subjective observations of ovarian tissue and on the behavior of extremely rare ovarian cells following extensive growth in tissue culture, a procedure that is capable of «reprogramming» cells.

Based on anatomy and molecular markers, we propose that it arose by duplication of a neighboring stem cell, which may have enabled finer neuronal control over leg - related behaviors, such as walking and grooming.»

The researchers also discovered an essential role for the mechanical properties, i.e. the physical stiffness, of the gel in regulating intestinal stem cell behavior, shedding light on how cells are able to sense, process and respond to physical stimuli.

On the other hand, when the researchers blocked f - circRNA activity, the cells» normal behaviors were restored.

Using juvenile and adolescent mice, Jeffrey Edwards and colleagues investigated the effects of tetrahydrocannabinol (THC), the chemical in marijuana responsible for its effects on cognition and behavior, on VTA GABA cells, an understudied inhibitory cell type in the reward system that regulates dopamine levels.

His research group focuses on big data network biology, exploring biological systems by developing and deploying algorithms aimed to predict cell behavior, in particular looking at cellular signal processing and decision making.

«We wanted to understand how the monarch is processing these different types of information to yield this constant behavior — flying southwest each fall,» said Shlizerman, who is lead author on the team's recent paper in the journal Cell Reports.

They used their method to trace the lineages of 295 neuroblasts (precursors of nerve cells) and discovered that it is possible to predict the future fate and function of many cells based on their early dynamic behavior.

For another, although the unusual T cell behavior was entirely absent in kids who didn't get autoantibodies later on, it was recorded in only about half who did.

A strategic focus is to continue to develop computational tools (such as KinomeXplorer, NetworKIN, and NetPhorest) and to deploy these on genome - scale quantitative data obtained by, for example, mass spectrometry, genomic, and phenotypic screens to understand the principles of how spatio and temporal assembly of mammalian signaling networks transmit and process information at a systems level in order to alter cell behavior.

The new research finds that the stiffness of the extracellular matrix and the availability of certain ligands (molecules that bind to cell membranes) can together determine which genes are actually called on — and whether normal epithelial cells begin to exhibit the behaviors characteristic of highly malignant cancer cells.

However, due to technological limitations, previous genetic studies largely focused on mixed populations of cells, obscuring critical nuances in cellular behavior.

The study, «Modulating Behavior in C.elegans Using Electroshock and Antiepileptic Drugs,» just published in PLOS One, has led the researchers to build on the current animal models for inducing seizures via electroconvulsion in the genetically modifiable C.elegans that only has 302 brain cells called neurons.

To tie the mechanism to behavior, he says, researchers still must try to disrupt the cells and show an effect on navigation.

This behavior can be exploited in microbial fuel cells, with a special focus on wastewater treatment schemes.

«The dose of transplanted bone marrow has strong and lasting effects on how HSCs specialize and coordinate their behavior,» said Rong Lu, senior author and assistant professor of stem cell biology and regenerative medicine.

Thomas L. Kash, PhD, associate professor of pharmacology and the lead author of the study published in the journal Cell Reports, used mice to show the effects of KORs on behavior.

Dr. Christie's research team will further investigate the activity of Purkinje Cells in motor learning and the potential modifications in their activity caused by a perturbation on their behavior.

On the material side, it's creating the right materials that are highly biocompatible and that stimulate the right growth and cell behavior.

The firing of the anxiety cells sends messages to other parts of the brain that turn on anxious behaviors — in mice, those include avoiding the dangerous area or fleeing to a safe zone.

When an enzyme that normally breaks down 2 - AG was blocked, and the supply of the endocannabinoid was restored to normal levels, these behaviors were reversed, the researchers reported on Nov. 26 in the online edition of the journal Cell Reports.

«These response behaviors, in two separate species of animals, validate that the cells containing the synthetic gene turn on in a magnetic field,» Wheeler noted.

The vectors also contained DNA bar codes, sequences that the researchers could look for later to determine which small RNAs were having a big effect on a cell's behavior.

The wiring diagrams look like colorful threads on a tapestry, and they're clear enough to show which cell clusters control specific behaviors.

How is it that cells can change their behavior based on signals from their neighbors, or even cells in entirely different parts of the body?

Thomas L. Kash, PhD, associate professor of pharmacology and the lead author of the study published today in the journal Cell Reports, used mice to show the effects of KORs on behavior.

The information gathered by your senses is transmitted by nerve cells, or neurons, to specific brain regions where the signal is routed through circuits and sent downstream to areas that essentially translate the information into behavior and get you back on track.

Supported by National Institutes of Health grants, researchers at Oak Ridge National Laboratory (ORNL), the University of Tennessee (UT), and the UT — ORNL Joint Institute for Computational Sciences (JICS) discovered a molecular «switch» in a receptor that controls cell behavior using detailed molecular dynamics simulations on a computer called Anton built by D. E. Shaw Research in New York City.

«On the symmetry of siblings: automated single - cell tracking to quantify the behavior of hematopoietic stem cells in a biomimetic setup» is featured on the February issue coveOn the symmetry of siblings: automated single - cell tracking to quantify the behavior of hematopoietic stem cells in a biomimetic setup» is featured on the February issue coveon the February issue cover.

By turning the anxiety cells off and on using a technique called optogenetics, which allows scientists to control the activity of neurons using beams of light, the researchers demonstrated that the anxiety cells control anxiety - related avoidance behaviors.

To this end, we are developing a new multi-scale live imaging approach to characterize nuclear organization dynamics at the single cell level based on the simultaneous characterization of both the local dynamics of RNA polymerases and transcription factors and the large scale behavior of chromatin.