Sentences with phrase «on cell metabolism»

Carbohydrate availability and training adaptation: effects on cell metabolism.

Aguayo - Mazzucato was lead author on the Cell Metabolism paper.

Peg 3 enhances cell reprogramming by acting on cell metabolism.

An acid condition has several adverse effects on cell metabolism, including impaired energy production, fluid accumulation and edema, and a likely increase in free radical production.

Not exact matches

Maybe Brussel sprouts weren't on your greens list for starting a post-holidays detox, but I'm about to turn those feelings around, with this creamy, comforting soup, flavoured with Ayurvedic spices to kick start your metabolism and help your body cells cleanse naturally.

Maybe Brussel sprouts weren't on your greens list for starting a post-holidays detox, but I'm about to turn those feelings around, with this creamy, comforting soup, flavoured with Ayurvedic spices to kick start your metabolism and nourish your body cells.

The hope is that 3BP specifically kills certain cancer cells — while leaving normal cells alone — because they rely more on glucose metabolism than on an alternative pathway called oxidative phosphorylation.

The study, recently published in Cell Metabolism, also found that beige fat, unlike the better - known white and brown fat, has interesting anti-diabetic effects on blood sugar metabolism that seem independent of temperature rMetabolism, also found that beige fat, unlike the better - known white and brown fat, has interesting anti-diabetic effects on blood sugar metabolism that seem independent of temperature rmetabolism that seem independent of temperature regulation.

Calcium, however, puts a strain on cells — it is known to hinder protein - folding and metabolism when it accumulates — disrupting normal cellular function.

Researchers measure the impact on cancer stem cell metabolism of 3 natural substances, 3 experimental pharmaceuticals and 1 clinical drug.

Investigators focused on the tumor suppressor liver kinase B1 (LKB1), a protein that controls cell growth and metabolism.

The cause of this phenomenon has so far been attributed to the thyroid hormones» general effect on the metabolism in the cells themselves.

These techniques include: human tissue created by reprogramming cells from people with the relevant disease (dubbed «patient in a dish»); «body on a chip» devices, where human tissue samples on a silicon chip are linked by a circulating blood substitute; many computer modelling approaches, such as virtual organs, virtual patients and virtual clinical trials; and microdosing studies, where tiny doses of drugs given to volunteers allow scientists to study their metabolism in humans, safely and with unsurpassed accuracy.

The results are important, according to the authors, because they deepen our understanding of conditions on Earth when all life consisted of single - cell microbes and their metabolisms that we know today were only just emerging.

Building upon their earlier research on the biology of fat metabolism, Joslin scientists discovered that microRNAs - small RNA molecules that play important roles in regulation in many types of tissue — play a major role in the distribution and determination of fat cells and whole body metabolism.

Kim and his colleagues are planning to continue their studies of pancreatic and islet - cell development as part of a Stanford focus on diabetes and metabolism research.

The cells enlarge, develop complex elements that enable them to contract, and switch from a metabolism that depends on glucose for most of its energy to a metabolism that derives most of its energy from fats.

On the other hand, when they increased let - 7 levels, the cells switched to a fatty acid - based metabolism and became larger, stronger and structurally and functionally more mature.

More work is needed to determine whether the findings on rapamycin hold true in animal models of Leigh syndrome and other neurodegenerative diseases, and to ascertain how exactly rapamycin is altering the metabolism of the cells.

In their efforts to conquer the aging process, researchers are zeroing in on one specific part of the cell: mitochondria, the energy - generating organelles that control our metabolism and, it seems, help regulate how long we live.

We would know the basic structure of every last one of its proteins: every enzyme in its metabolism, every signal - bearing hormone coursing through its body, every receptor poised to receive those signals on the surface of its cells.

After completing her graduate studies in 2006, she joined the laboratory of Dr. Craig B. Thompson at the University of Pennsylvania for postdoctoral work focusing on cancer cell metabolism.

We also observed a strong increase in the production of GLP1 in the gut cells, thus proving the crucial role of the intestine in the control of carbohydrate balance and the influence of estrogens on the entire metabolisms at stake.»

In a study published today in Cell Metabolism, UT Southwestern researchers identify a hormone that acts on the brain to increase the desire to drink water in response to specific nutrient stresses that can cause dehydration.

In addition to 6 - PN, Bolton and her colleagues studied 8 - prenylnarigenin (8 - PN), isoxanthohumol (IX) and xanthohumol (XH) for their effects on estrogen metabolism in breast cells.

Craig Thompson, president of the Memorial Sloan - Kettering Cancer Center in New York City, yesterday was hit with a second lawsuit alleging that he made an improper business deal to exploit his research on the metabolism of cancer cells.

When temperatures drop below freezing, the frog's metabolism eases to a near halt, so its cells can survive on negligible amounts of oxygen and energy.

Lead author Nora Volkow, a psychiatrist at the National Institute on Drug Abuse of the National Institutes of Health, recruited 47 healthy volunteers and used positron emission tomography (PET) scans to measure glucose metabolism in the brain while cell phones were placed over the right or left ear.

He and his colleagues report their results on 19 May in Cell Metabolism.

«Boosting serotonin signaling has been seen as a viable strategy for weight loss in people, but our results hint that boosting serotonin plus adrenaline should produce more potent effects — and there is already some evidence that that's the case,» said TSRI Assistant Professor Supriya Srinivasan, who was principal investigator for the study, published online before print on October 10, 2013 by the journal Cell Metabolism.

The results, revealing new examples of heritable bacterial species — including those related to diet preference, metabolism, and immune defense — appear May 11 in Cell Host & Microbe's special issue on the «Genetics and Epigenetics of Host - Microbe Interactions.»

The structure of this complex, determined using cryo - electron microscopy, shows how it converts near - infrared light into an electrical charge in order to power cell metabolism, which enables this bacterium to live at the extreme red limit of photosynthesis on Earth.

The basics of glycogen biology are thought to be well established, but a study in rodents published July 5th in the journal Cell Metabolism turns long - standing assumptions on their head.

The research was published online on October 8th in the journal Cell Metabolism.

They were surprised to discover that it also had an enormous impact on metabolism in cells — how fast cells can convert nutrients into energy — throughout the course of a day.

«This study breaks new ground because it focuses on boosting beta cell performance and shows that beta cell preservation is possible even in the face of such immune attack,» said senior author Gökhan S. Hotamisligil, chair of the Department of Genetics and Complex Diseases and J.S. Simmons Professor of Genetics and Metabolism at HSPH.

In Cell Metabolism on August 13, the Harvard scientists who discovered irisin address this contentious issue by showing that human irisin circulates in the blood at nanogram levels and increases during exercise.

The light or «autoflorescence» produced changes according to the chemical reactions or metabolism going on in the cell.

In this schematic of the new «liver on a chip» device, adding blood - sugar - raising glucagon to inlet 1 and blood - sugar - lowering insulin to inlet 2 distributes the hormones across the field of hepatocytes (purple box) along opposing gradients, altering the cells» metabolism from glucose release on the left side to glucose uptake on the right.

«Additionally, we showed that obesity increases the number and activity of NK cells in abdominal fat but not in other tissues,» says Lee, senior author on a paper published online in Cell Metabolism.

«Conversely, the necrotic part of the tumor is driven by a distinct set of glioma stem cells utilizing the BIM1 pathway and are characterized by a mesenchymal, inflammatory cell type dependent on glucose metabolism in the absence of oxygen.

Not only were levels of metabolic compounds different, but the expression of certain genes involved in metabolism was turned up, and the epigenome of the cells — molecular markers on DNA that change gene expression on a broader scale — was altered.

«Our original hypothesis was that cancer cells were modifying their metabolism based on communications they were receiving from cells in the microenvironment near the tumor,» said Nagrath, assistant professor of chemical and biomolecular engineering at Rice and co-author of a new study describing the research in the open - access journal eLife.

«Some studies suggested that exosomes harbored the potential to regulate cancer cell metabolism, but most research had focused on the exosomes that were produced and emitted by cancer cells themselves.

Now, however, a team of researchers led by Yu - Hua Tseng, Ph.D., Investigator in the Section on Integrative Physiology and Metabolism at Joslin Diabetes Center and an Associate Professor of Medicine at Harvard Medical School, has created cell lines of human brown and white fat precursor cells that will help investigators to pick apart the factors that drive the development and activity of each type of cell.

Zinc finger nuclease mediated knockout of ADP - dependent glucokinase in cancer cell lines: effects on cell survival and mitochondrial oxidative metabolism.

Their work was reported online in the journal Cell Metabolism on November 30.

Yu - Hua Tseng, Ph.D., is an Investigator in the Section on Integrative Physiology & Metabolism at Joslin Diabetes Center, Assistant Professor of Medicine at Harvard Medical School, and Principal Faculty of the Harvard Stem Cell Institute.

So what I mean by that is, metabolism is basically the housekeeping chemical processes that are going on in the cell.

Better understanding of the beta - cell proliferation process eventually may lead toward therapies for diabetes patients, whose supplies of these cells often shrink over time, says Rohit Kulkarni, M.D., Ph.D., a Joslin Senior Investigator and senior author on a paper about the work published in the journal Cell Metabolcell proliferation process eventually may lead toward therapies for diabetes patients, whose supplies of these cells often shrink over time, says Rohit Kulkarni, M.D., Ph.D., a Joslin Senior Investigator and senior author on a paper about the work published in the journal Cell MetabolCell Metabolism.