The planarian Schmidtea mediterranea are flatworms with bilateral symmetry used as models in the research
on cell regeneration and stem cells.
Not exact matches
On the logistics end, it is easier to manufacture certain stem -
cell therapies, which will be key for human trials like the heart - muscle -
regeneration program.
Low - power laser light shined
on damaged rat teeth activates growth factors that cue stem
cells to generate the tooth constituent dentin, leading to
regeneration.
Her PhD is focused
on developing a novel label - free imaging approach for assessing human stem
cells and skeletal
regeneration non-destructively and non-invasively.
Today is the 70th birthday of Elizabeth Hay, an embryologist at Harvard Medical School who, through pioneering studies
on regeneration of amphibian limbs, has shed light
on the cellular mechanisms that transform normal
cells into tumors.
Get a cut
on your finger and your skin can make new
cells to heal the wound; lose your tail — if you are a particular kind of lizard — and tissue
regeneration may produce a new one.
Building
on the evidence that microglia were in play during injury, the researchers conducted tests in zebrafish with the specialized enzyme incorporated into both rod
cells and microglial
cells, removing both
cell types to ask what role microglia play during
regeneration.
Mark Poznansky, MD, PhD, director of the MGH - VIC and senior author of the Wound Repair and
Regeneration report adds, «Having a novel therapeutic that is based
on the immediate isolation of a patient's own
cells, with minimal manipulation, will represent an attractive option for the wound care field; and a successful option that accelerates healing would greatly benefit patients, as diabetic ulcers typically need up to a year or more heal.
Weissman says that most clinical studies of stem
cells fail to meet what he sees as key criteria: They should be based
on clear, peer - reviewed demonstrations of tissue
regeneration, replicated by a large number of independent groups that provide rapid, long - lasting benefits.
Previous research has described at least some of the fundamental processes involved in healthy,
on - going peripheral nerve growth
regeneration, including the critical role of mitochondria — cellular organelles that produce adenosine triphosphate (ATP), the energy - carrying molecule found in all
cells that is vital to driving nerve recovery after injury.
«Our results suggest that megakaryocytes might be used clinically to facilitate adult stem
cell regeneration and to expand cultured
cells for adult stem
cell transplants,» says Meng Zhao, Ph.D., a postdoctoral fellow at Stowers and lead author
on the study.
«The
cell puts up a stop sign
on the
regeneration pathway that serves as a «wait, I'm not ready yet» sign,» Lin said, speculating that if the stop sign is removed, «that will speed up traffic, in this case speeding up
regeneration.»
Aurora kinase has many subtypes, but is generally known for its role in
cell division — an additional link between
regeneration and division that helped to confirm Lin was
on to something.
which is focused
on mouse models of adult stem
cell differentiation and tissue
regeneration.
Normal maintenance and
cell turnover throughout the planarian body continue unaffected when fst is inhibited, even though these activities rely
on the same neoblast
cell population that creates new tissue during
regeneration.
The authors were led into the realm of muscle and sex when they realized that they were relying heavily
on cell lines derived from female mice to study muscle
regeneration.
On the other hand, genetic mutations that further promote the growth of intestinal stem
cells are associated with uncontrolled organ
regeneration and the development of colon cancer.
Discussion themes included: - stem
cell heterogeneity - stem
cell fate decisions - stem
cells in
regeneration & development - stem
cells in disease & treatment - stem
cell related bioengineering & biomaterial - theoretical stem
cell biology - mathematical modelling with a focus (but no restriction)
on neural stem
cells, hematopoietic stem
cells and diabetes.
Most of the scientific focus to date has been
on trained
on the blastema, a remarkable cluster of
cells that forms at the base of an amputated limb or damaged tissue and is the modus operandi for
regeneration.
The influence of cellular source
on periodontal
regeneration using calcium phosphate coated polycaprolactone scaffold supported
cell sheets.
Towards our goals we study retinal
cells throughout their life, from embryonic stem
cells to retinal progenitors to differentiating and mature neurons and glia — with one eye
on neuronal
regeneration (meaning de-novo neurogenesis) in the mammalian retina — and with another eye
on retinal disease pathomechanisms.
To this end, we are focusing
on two aspects of β -
cell regeneration: enhancing β -
cell proliferation in vivo and stimulating the differentiation of new β -
cells from endogenous progenitors in the pancreas.
EMBO Conference - Advances in Stem
Cell Research: Development,
Regeneration and Disease The 3rd event in this EMBO Conference Series
on Stem
Cells.
His research is focused
on retinal
regeneration by reprogramming human fibroblasts either into induced pluripotent stem
cells or directly into photoreceptors.
In the October 28th issue of
Cell, Bi-Sen Ding, PhD, a NYSCF — Druckenmiller Fellow in Dr. Shahin Rafii's laboratory at Weill Cornell Medical College, presented the discovery of signals that «turn
on»
regeneration of oxygen - exchanging sacs in the lungs.
The ability to switch
on and mobilise resident stem
cells in
regeneration will be important in a wide range of new therapies, particularity for organs affected by injury or disease.
During this time, her research focused
on nutritional modulation of olfactory function, neuronal development and
regeneration, and chemosensory
cell biology.
Topics such as the mechanisms of
cell injury in normal and dystrophic muscle, compensatory muscle
regeneration and hypertrophy, and the effects of various therapies or voluntary exercise
on muscle repair, satellite
cell activation, muscle growth, bone density and age - related atrophy are examined using a large variety of cellular, molecular and whole - animal in vivo assays of function.
Studies of satellite
cell activation via nitric oxide have opened an exciting area of research
on muscle
regeneration, growth and the muscle - fiber cytoskeleton that integrates mechanical and biochemical signal transduction with
cell and molecular biology of muscle tissue in growth, development, disease, aging and evolution.
For more
on this simple and effective approach to promote kidney
regeneration, stay tuned to the Stem
Cells Portal!
Review of «The Effects of Platelet - Derived Growth Factor - BB
on Human Dental Pulp Stem
Cells Mediated Dentin - Pulp Complex Regeneration» from STEM CELLS Translational Medicine by Stuart P. Atk
Cells Mediated Dentin - Pulp Complex
Regeneration» from STEM
CELLS Translational Medicine by Stuart P. Atk
CELLS Translational Medicine by Stuart P. Atkinson
The safety and efficacy of using embryonic and other stem
cells for tissue
regeneration will depend
on harnessing and precisely controlling their proliferative capacity.
He has also made fundamental contributions to understanding the role of apoE in the nervous system, specifically in nerve injury and
regeneration and in the remodeling of neurites
on neuronal
cells.
Suzuki, possibly inspired by his new job as a research scientist at the Research Unit for Organ
Regeneration in Kobe, Japan, explains it this way: «Just as humans can start over in life, differentiated
cells can also take
on other fates following the generation of undifferentiated stem
cells.»
Two studies find adult pancreatic
cells maintain islet population, contradicting a hypothesis that
regeneration relies
on stem
cells
Ettema Lab is pleased to announce the new paper in Current Biology by Henning Onsbring Gustafson
on cellular
regeneration in the ciliate Stentor at single
cell resolution.
Stewart discovered that the histone modifications that poise embryonic stem
cell - specific genes for activation are also found
on the histones near genes involved in
regeneration, putting them into a ready - to - go state.
√ SLATHER
ON THE BENEFITS: Rich in antioxidants, vitamin A, E and C; retain and maintain moisture, promote healthy hair growth and
cell regeneration, and protect from sun damage - Simply cut into small chips or wafers, rub in your hands until soft, and apply to skin for benefits
Your skin relies
on you to provide it with the necessary nutrients it needs for proper
cell repair and
regeneration, moisture, and a healthy radiant glow.
Cell energy (of which in their study
on bone
regeneration creatine played a major role) is important for bone development and maintenance, and therefore directly related to osteoporosis.
It causes them to grow to an enormous size, act out aggressively and take
on the genetic qualities of other animals, like rapid
cell regeneration, or exploding porcupine quills, or, you know, flying.
By using stem
cells in an area of the body that requires healing, they will go to work
on that area, greatly enhancing the process of
regeneration.
Programs with research emphasis
on signal transduction in development and oncogenesis,
cell adhesion molecules in development and oncogenesis, muscologskeletal atrophy and countermeasures, ovarian follicle development, neural
regeneration, implantable therapeutic or diagnostic devices and application of computers in veterinary education.
On Houston's Clear Thinkers, Tom Kirkendall ponders the view of cancer as tenaciously persistent and able to regenerate after apparently disappearing — driven by a specific
cell type lurking within the cancer that is capable of dormancy, growth and infinite regeneration — a cancer «stem cell» in The Cancer Sleeper
cell type lurking within the cancer that is capable of dormancy, growth and infinite
regeneration — a cancer «stem
cell» in The Cancer Sleeper
cell» in The Cancer Sleeper
CellCell