Sentences with phrase «on cell surface»

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Multiple round bumps on cell surface A video by Gay Men's Health Charity sees men reading out the mean messages they've been sent online - including «Sluts like you deserve it» and «Are you

Multiple round bumps on cell surface Muluba Habanyama was born HIV - positive.

Multiple round bumps on cell surface

They bind to receptors on the cell surface and tell other cells and molecules what to do.

Glucose is carried into cells by the hormone insulin and its interaction with the insulin receptor on the cell surface.

Curcumin inhibits interleukin 8 production and enhances interleukin 8 receptor expression on the cell surface: impact on human pancreatic carcinoma cell growth by autocrine regulation.

Innate dendritic cells engulf and partially digest antigens (pathogens like our virus) and present a piece of that antigen on their cell surface, waving it like a flag for other immune cells to see.

ABCA1 mediates unfolding of apoAI N - terminus on the cell surface prior to lipidation and release of nascent HDL.

In fact, internalization of the prepared nanoparticles may depend on various factors, one being surface charge of nanoparticles, another one being the presence of specific receptors on cell surface and finally, it will also depend on the composition of the protein corona [30]- [32].

When α or β secretase cleave APP on the cell surface, the N - term mCherry containing domain is released into the medium and the 1:1 fluorescence intensity ratio between the red and green channels is lost.

However, in a 2014 study, Dr. Sulzer's lab demonstrated that dopamine neurons (those affected by Parkinson's disease) are vulnerable because they have proteins on the cell surface that help the immune system recognize foreign substances.

The model predicted that the time scales of receptor (de) activation kinetics on the cell surface and the interior compartments were comparable.

Proteins on the cell surface can detect that bacteria are present and mount a weak and transient defense called pattern - triggered immunity (PTI).

Like in the Wnt signaling pathway, ligands bind to the EGFR on the cell surface and initiate a cascade of events in the cell that in this case lead to regulation of genes that control cell cycle progression.

It's also been postulated that the leptin receptor binds to a leptin co-receptor on the cell surface.

IHC can be used to show whether cancer cells have HER2 overexpression and / or hormone receptors on the cell surface.

The Wnt proteins bind to receptors on the cell surface.

The neurotransmitter molecules act on the post-synaptic cell by binding to specific receptors on the cell surface (purple).

Based on cell surface markers known as CD4 and CD8, T cells generally fall into two broad categories: CD4 — positive helper T cells, which ¬ help activate other immune cells and CD8 - positive cytotoxic T cells, which kill cells that are cancerous or infected with viruses.

They receive signals from outside the cell via partner receptors on the cell surface, and G - proteins help deliver those signals to their proper destinations within the cell.

These chains are present on the cell surface and are crucial for many biological processes, including cell adhesion and signal transduction.

The mRNA directs cells to produce and express the proteins on the cell surface, much like a native infections would do, but without the ability to cause disease.

Clone 1022 cells ezpress human CD4 protein on the cell surface and can be infected by most isolates of HIV.

The mRNAs are delivered to the body and direct cells to produce and express both antigenic proteins on the cell surface, much like a native infection would do but without the ability to cause disease or spread.

The team chose integrin receptors that control a variety of functions on the cell surface as a target for their peptides.

However, this is unlikely given that the frequency of in - frame mutations remained stable over nearly four weeks in culture, that there was no significant increase in cell death between control cultures and those treated with X4 - ZFNs, and that the most common in - frame mutant was not expressed on the cell surface and thus can not maintain functionality.

WtCXCR4 was detected equally by both antibodies on the cell surface (middle panel, top row) and intracellularly (middle panel, lower row).

These effects can be seen as a general response to the primitive signal conveyed by NGF through its specific receptors on the cell surface.

This physical change causes adhesion receptors on the cell surface called integrins to clump together.

The virus seemed to trigger and enter through a balloonlike structure, or bleb, on the cell surface, which normally only forms during cell movement, division, or death.

The group was then able to sort the cells using markers expressed on the cell surface, to help pull out successfully edited cells for research, and eventually for therapeutic use.

«Changes to the sugar composition on the cell surface could alter physically how receptors are organized,» he said.

The R117H mutation, carried by about 3 percent the CF population, creates a protein that reaches its destination on the cell surface, but then malfunctions.

To identify which structure on the cell surface helped it enter the cell, Raines screened 264 structures using a specially designed chip.

«It took us around four years to discover that phthalocyanine, which is a blue paint used on the surface of the Japanese bullet trains and road signs, could bind competitively to the HasA protein,» adds Ms. Chikako Shirataki, a PhD student in her final year, «crystal structures of metal protein complexes helped us to show that the phthalocyanine - bound HasA protein blocks the receptors on the cell surface of the bacterium and thus, inhibits the uptake of heme.»

When applied to neurons in cell culture, the antibody locked onto a protein on the cell surface.

The cancer cell marker that Johnson and her team identified was a specific change in protein glycosylation, that is, a unique pattern of sugars decorating a protein found on the cell surface.

In earlier research, Barbolina discovered that a fractalkine receptor — a protein found on the cell surface — is expressed in the majority of ovarian cancer cases.

Integrins are proteins on the cell surface that attach to and interact with the cell's surroundings.

(Right) In a liver with HCC, AIM accumulates on the cell surface, resulting in the activation of the complement cascade and inducing necrotic cell death.

This antibody activates an integrin on the cell surface of basal progenitors and thus stimulates their proliferation,» explains Denise Stenzel, who headed the experiments.

Plasmodium parasites infect human red blood cells and gain entry via receptors on the cell surface.

The impulses cause glutamate (one of the brain's main neurotransmitters) to pop out of one nerve cell and travel across the synapse to activate the next by binding to its receptors, chemically active signaling stations on the cell surface.

A protein on the cell surface of P. syringae binds water in a way that mimics the structure of an ice crystal, and this helps start the transformation of cold water into ice.

Like many other fungi, Baker's yeast has mating receptors, proteins on its cell surface that detect pheromones released by potential partners.

Measuring changes in a voltage bias applied to the saline reveals how close the capillary tube is to the cell, allowing researchers to scan subtle structures on the cell surface without disrupting them.

disruption of the cell wall barrier by reactions of chlorine with target sites on the cell surface

Researchers already knew that there was a time lag of between 1 and 3 hours between the synthesis of Class II molecules within the APC and their appearance on the cell surface, combined with antigen.

Researchers found that in N. gonorrhoeae, BamE is exposed on the cell surface but is not essential for cell viability.