This metabolic demand makes brain cells particularly vulnerable to damage from oxidative stress, in which reactive oxygen species (ROS), sometimes called free radicals, exert toxic effects
on cellular components.
Not exact matches
Succinic acid, a natural healing oil is a
component found in plant and animal tissues and has a very positive effect
on cellular metabolism.
This year's Nobel Prize in Physiology or Medicine has been awarded to Yoshinori Ohsumi, a cell biologist at the Tokyo Institute of Technology's Frontier Research Center, for his work
on autophagy, the process in which cells degrade and recycle
cellular components.
This latter capability is extremely valuable to biomedical research, which relies heavily
on fluorescent probes to label and track proteins, nucleic acids, and other
cellular components.
(The markers include genes and other DNA
components, such as parts of the DNA that turn proteins
on or off, and
cellular components that play a role in regulating genes.)
Sphingolipids are vital
components of
cellular membranes but their production relies
on toxic intermediates: ceramides.
His lab went
on to molecularly decode a number of new
components of this
cellular starvation pathway, which connects nutrition and exercise to suppression of both cancer and diabetes.
The BioVacSafe project will draw
on the latest life science research findings to profile how individuals respond to the different
components of vaccines at the
cellular, genetic and molecular level.
Our company focuses
on the development of innovative immunotherapies for cancer based
on genetically engineered lymphocytes and
cellular components of the tumor microenvironment.
From the European Commission Research & Innovation website: «Study investigates aquatic parasites
on fish», Researchers in the Czech Republic, Spain and the United Kingdom have successfully identified the
cellular components and mechanisms that play a role in the proliferation of myxozoa, tiny aquatic parasites responsible for diseases in commercially valuable fish.
Certain particle compounds may directly generate ROS in vivo because of their surface chemistry (eg, metals, organic compounds, and semiquinones) or after bioactivation by cytochrome P450 systems (eg, polycyclic aromatic hydrocarbon conversion to quinones).6, 290 a, 290 b A particle surface or anions present
on otherwise more inert particles may disrupt iron homeostasis in the lung and thereby also generate ROS via Fenton reactions.291 Other PM constituents may do so indirectly by the upregulation of endogenous
cellular sources (eg, nicotinamide adenine dinucleotide phosphate [NADPH]-RRB- oxidase) 292,293 or by perturbing organelle function (eg, mitochondria) by taken - up PM
components.261 Particle stimulation of irritant and afferent ANS fibers may also play a role in local and systemic oxidative stress formation.294 Given the rich antioxidant defenses in the lung fluid, secondarily generated oxidization products of endogenous molecules (eg, oxidized phospholipids, proteins) or a reduction in endogenous antioxidants per se may be responsible at least in part for the state of oxidative stress in the lungs (along with instigating the subsequent
cellular responses) rather than ROS derived directly from PM and its constituents.
For starters, drinking water
on an empty stomach will purify your colon, enabling better absorption of nutrients all throughout the day, encourage the production of hematopoiesis (the formation of blood
cellular components) and fire up your metabolism, thereby priming your entire internal system for a great beginning of the new day.
Most recently, Spanish researchers publishing in the journal Molecules reported that the various
components of olive oil including oleic acid and secoiridoids protect your body
on the
cellular level to slow the aging process.