Sentences with phrase «on cellular machinery»

The CRISPR system relies on cellular machinery that bacteria use to defend themselves from viral infection.

When cells become cancerous, tremendous stresses are placed on the cellular machinery responsible for maintaining protein equilibrium — and that machinery is the target of anti-cancer drugs called proteasome inhibitors.

Not exact matches

Finally, the most absurd feature of your scenario is the idea that any extraterrestrial creature would just happen to have, first, DNA as it's basic molecule of biological information storage, second, cellular machinery anywhere remotely similar to what animals on Earth have, and finally, would just happen to be close enough genetically to be able to mix their DNA with the DNA of any terrestrial being, and come out with a viable result.

To date, much of the research on irradiation's effects on the cellular microenvironment has dealt with samples that included cells, obfuscating the irradiation's effect on just the ECM rather than the cell's internal machinery.

«If we can find molecules that modulate membralin, or identify its role in the cellular protein disposal machinery known as the endoplasmic reticulum - associated degradation (ERAD) system, this may put the brakes on neurodegeneration.»

Its cellular machinery will execute the program by producing the same protein as the native organism, taking on new qualities, just as in recombinant techniques.

Using new technologies for labeling cellular machinery with light - activated fluorescent markers, they could «turn on» just one molecule at a time.

This typical, casual canteen chat only partly reveals the facility's successful lab culture, which encouraged Ramakrishnan to focus on understanding the ribosome, the cellular machinery that turns RNA into protein.

«When we study the interactions between the host cell and the virus, we get information about both of them and about how cellular machinery is working under viral infection,» says Alessia Ruggieri, a group leader and virologist at University of Heidelberg in Germany and senior researcher on the study.

Particular cellular machinery needs to be «switched on» and that is what we try to understand.

These CARs contain two fused parts: an antibody that protrudes from the surface of a T - cell to recognise a protein on cancerous B - cells (commonly CD - 19) in the blood and a receptor inside the T - cell that sends messages to cellular machinery.

For me this revealed to be a very cool project, since it challenged evolution and I could test hands on how perfect the cellular machinery is in avoiding endangering itself with the incorporation of important epigenetic nucleotides.

Moderna's mRNA Therapeutics ™ platform builds on the discovery that modified mRNA can direct the body's cellular machinery to produce nearly any protein of interest, from native proteins to antibodies and other entirely novel protein constructs with therapeutic activity inside and outside of cells.

However, these two life - sustaining processes, which often unfold simultaneously on the strands of DNA, pose a spatial quandary: The cellular machinery that replicates DNA and the one that transcribes genes can collide head - on, destabilizing the genome with disastrous consequences.

Although the researchers found no change in the coding region of the gene, they did find that autistic children were much more likely to have inherited a shortened form of the genes promoter — the DNA sequence that serves as the on ramp for the cellular machinery that will express the gene.

We humans have descended from organisms that adapted to living in a prokaryotic world, and we humans retain (conserved in evolutionary terms) in our Eukaraotic mitochondria the cellular machinery to power our cells that we inherited (i.e., Endosymbiosis) from the prokaryotes of deep time on earth.

My research is framed within the Wellcome Trust consortium on the archaeal origins of eukaryotic cell organization (http://evocyt.com/), which includes a diverse group of researchers studying the evolution of eukaryotic machinery from different points of view — e.g. how do specific cellular systems work in different lineages, and how did that affect the origin of the eukaryotic cell plan?

So personally, if I already had the disease, and wanted to clean out and retool the cellular machinery as efficiently as possible, I would choose less saturated fat rather than more and leave out the oil, again based on what we know of the mechanisms of saturated fat induced insulin resistance.