Sentences with phrase «on chemical signals»

By showing that cancer cells were not autonomous and self perpetuating, as previously believed, but were dependent on chemical signals, such as hormones to grow and survive, and that depriving cancer cells of those signals could restore the health of patients with widespread metastases, Dr. Huggins provided an immense stimulus to research on cancer chemotherapy.

Many insects rely on chemical signals to attract mates.

Experiments in the lab and in the field showed that termites eavesdrop on the micro-vibrations made when ants move around, rather than on chemical signals.

Not exact matches

It «will either be a one - time, one - off, fire - and - forget retaliation for a heinous chemical - weapons assault on civilians, or it will serve as a signal to the Assad regime and its allies that the free ride for mass murder in Syria is now over,» Hof said.

The human body has about 1,000 kinds of such receptors, structures on the surface of cells, which let the body respond to a wide variety of chemical signals, like adrenaline.

Based on this Varendi et al (1994) stated that unnecessary routine cleaning of the breast may interfere with the establishment of successful early breastfeeding by elimination of the infant's access to biologically relevant chemical signals.

One of the most prominent was Senate Majority Leader Mitch McConnell, who on Friday tweeted out his support for Trump's strike, writing, «This was a clear signal from America that Bashar al Assad can no longer use chemical weapons against his own people with impunity.»

There, depending on what other chemical signals are present, the GAPDH can either stimulate the neuron's growth or activate a self - destruct program — called apoptosis — that will kill the neuron.

Based on their results and evidence from other studies on addiction and the hippocampus, the authors suggest an intriguing explanation for addiction: newborn neurons in the hippocampus inhibit the release of dopamine, one of the major chemical messengers that act as a reward signal.

The scientists observed that transmission of chemical signals between the nerve cells are facilitated by AMPA - receptors and the activity occurs on the brain cell surface.

By analyzing chemical changes of the IRS - 2 protein in immortalized cultures of human white blood cells, it determined that IRS - 2 appeared in two different forms — «on,» which allows the signal to pass through, and «off,» which stops the signal from activating the cells into M2 macrophages.

The brain uses the chemical to communicate between cells, and dopamine signals different events depending on its location.

The bacteria switches on this bad behavior by using a chemical signaling system known as quorum sensing.

Preti is hot on the scent of the human armpit because he believes that secretions from the so - called axillary region harbor pheromones, airborne chemical signals that influence mating, dominance, familyties, and maturation in other species of the animal kingdom.

Typical blood glucose testing strips also contain a molecule that ultimately amplifies the signal from the chemical reactions on the strip enough to register electronically on a monitoring device.

On further investigation, they discovered that, in fact, the conjoined amoebas actually send out a chemical distress signal, to which the midwives respond.

The goal was to set off a series of chemical explosions of different sizes and at different depths in the same borehole and then record the seismic signals on a battery of instruments.

The researchers speculated that brain cells might be particularly reliant on their mitochondria to power the production and recycling of the chemical signals they use to transmit information.

The researchers engineered a strain in which a Synechococcus gene normally turned on during photosynthesis signals its activity by switching on the gene for luciferase, an enzyme from another bacterium that drives a light - emitting chemical reaction.

When attractant or repellant chemicals attach themselves to receptor sites on the surface membrane of a bacterium, it triggers a process within the cell that leads to the modification of the signal protein, CheY (pronounced «Key - Y»), enabling it to bind to the switch and change the bacteria's direction of movement.

According to Hay, who is chairman of the Working Party on Chemical and Biological Weapons, a group of experts that monitors progress on the weapons treaties, Britain could give a «positive signal to other states by ratifying sooner rather than later».

Researchers think the crustacean is responding to either chemical signals or the touch of an algal cell on its antennae.

Now researchers say that some can even call for help: When chewed by tobacco budworms, many crops will send out a chemical distress signal to attract wasps that prey on the budworms.

Chemical marks on the histones, which sheathe our chromosomal DNA in each cell's nucleus, act as «stop» and «go» traffic signals.

Lu's team settled on a biological program that rewrites a living cell's DNA when the cell senses a signal — from a flash of light to the presence of a chemical.

Specialised cells that could carry messages using electrical impulses and chemical signals — the first nerve cells — arose very early on.

Autoinducers (chemical signaling molecules that produce more of themselves inside the cell) control the switch that turns the light genes off and on.

Because it is among the receptors targeted by the new class of antidepressants, they focused on mGluR5, which responds to a number of chemical signals.

Neurons communicate with each other through chemical and electrical signals that can be excitatory (activating) or inhibitory (deactivating), depending on their class: Pyramidal cells are excitatory neurons whilst interneurons are inhibitory.

Apparently, the irradiated cells pass on a distress signal or emit some chemical that breaks the DNA of neighboring cells (ScienceNOW, 7 September 2005).

About 30 percent of medications on the market activate G - protein coupled receptors on cell surfaces and trigger chemical signals inside cells to yield their therapeutic effects.

In response to the initial chemical signal, these cells take on the genetic signatures of two different cell types.

Seiden, 72, was one of the world's experts on how drugs, especially the amphetamines, could selectively damage certain neurons, particularly those that produced the neurotransmitters dopamine and serotonin — chemical signals that relay messages within the brain.

The electrical signals and chemical signatures that constitute the experience of the dream may disappear as wakefulness ensues, like a message written on a fogged mirror that vanishes as the steam evaporates.

The excited atoms, in turn, emit signals that can be used to create images of the brain, muscle, and other tissues, which can be distinguished based on the local physical and chemical environment of the water molecules.

Several types of chemical modifications of the five major histone protein families give rise to a complex «histone code» that signals the transcriptional machinery to turn genes on or off.

Ongoing research focuses on chemicals that alter Ca2 + signaling pathways essential physiological processes including neurodevelopment, striated muscle function and oocyte fertilization.

Visual signaling from biologically - inspired robots has been used to investigate the behavior of birds [27]--[31], dogs [32], lizards [33], fish [22], [34]--[42], and rats [43]; salient chemical cues have been implemented on a miniature mobile robot to investigate social behavior of cockroaches [44]; audio feedback has been integrated in a model of a robotic squirrel to influence squirrels» behavior [45]; pulsing air currents created by robotic honeybees have been used to investigate honeybees» dance [46]; and hydrodynamic cues from a swimming robotic fish have been considered in [20] to modulate fish behavior in a water tunnel.

C. elegans is a lab - friendly model species for research on how chemical signals affect development and behavior.

These chemical signals consist of both classical «fast acting» neurotransmitters such as glutamate and GABA that signal across synapses in milliseconds, as well as more than 100 diverse neuromodulators that can act on longer timescales.

During this time, he set out to elucidate the molecular basis of signalling in the nervous system, focusing specifically on how chemicals known as neurotransmitters are released at junctions between neurons called synapses.

In one on - going project, funded by Harvard University's Climate Change Solutions Fund (CCSF), Martin and his team are mapping and monitoring the unique chemical signals emitted by trees known as volatile organic compounds (VOCs).

Which animal a lab uses will depend on how closely parts of its body or chemical - signaling systems match those in people.

Susan Amara, USA - «Regulation of transporter function and trafficking by amphetamines, Structure - function relationships in excitatory amino acid transporters (EAATs), Modulation of dopamine transporters (DAT) by GPCRs, Genetics and functional analyses of human trace amine receptors» Tom I. Bonner, USA (Past Core Member)- Genomics, G protein coupled receptors Michel Bouvier, Canada - Molecular Pharmacology of G protein - Coupled Receptors; Molecular mechanisms controlling the selectivity and efficacy of GPCR signalling Thomas Burris, USA - Nuclear Receptor Pharmacology and Drug Discovery William A. Catterall, USA (Past Core Member)- The Molecular Basis of Electrical Excitability Steven Charlton, UK - Molecular Pharmacology and Drug Discovery Moses Chao, USA - Mechanisms of Neurotophin Receptor Signaling Mark Coles, UK - Cellular differentiation, human embryonic stem cells, stromal cells, haematopoietic stem cells, organogenesis, lymphoid microenvironments, develomental immunology Steven L. Colletti, USA Graham L Collingridge, UK Philippe Delerive, France - Metabolic Research (diabetes, obesity, non-alcoholic fatty liver, cardio - vascular diseases, nuclear hormone receptor, GPCRs, kinases) Sir Colin T. Dollery, UK (Founder and Past Core Member) Richard M. Eglen, UK Stephen M. Foord, UK David Gloriam, Denmark - GPCRs, databases, computational drug design, orphan recetpors Gillian Gray, UK Debbie Hay, New Zealand - G protein - coupled receptors, peptide receptors, CGRP, Amylin, Adrenomedullin, Migraine, Diabetes / obesity Allyn C. Howlett, USA Franz Hofmann, Germany - Voltage dependent calcium channels and the positive inotropic effect of beta adrenergic stimulation; cardiovascular function of cGMP protein kinase Yu Huang, Hong Kong - Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency, Endothelium - derived Contracting Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) traSignaling Mark Coles, UK - Cellular differentiation, human embryonic stem cells, stromal cells, haematopoietic stem cells, organogenesis, lymphoid microenvironments, develomental immunology Steven L. Colletti, USA Graham L Collingridge, UK Philippe Delerive, France - Metabolic Research (diabetes, obesity, non-alcoholic fatty liver, cardio - vascular diseases, nuclear hormone receptor, GPCRs, kinases) Sir Colin T. Dollery, UK (Founder and Past Core Member) Richard M. Eglen, UK Stephen M. Foord, UK David Gloriam, Denmark - GPCRs, databases, computational drug design, orphan recetpors Gillian Gray, UK Debbie Hay, New Zealand - G protein - coupled receptors, peptide receptors, CGRP, Amylin, Adrenomedullin, Migraine, Diabetes / obesity Allyn C. Howlett, USA Franz Hofmann, Germany - Voltage dependent calcium channels and the positive inotropic effect of beta adrenergic stimulation; cardiovascular function of cGMP protein kinase Yu Huang, Hong Kong - Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency, Endothelium - derived Contracting Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) trasignaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) trasignaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) trasignaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transporters

Insulin, on the other hand, acts as a chemical signal that allows sugar to enter your cells where it creates energy.

Everything in your body, from the tissue that supports your skeleton to the neurons that fire signals from your brain to your feet run on the energy that's created by the food we eat, and I personally would prefer to have body tissue made from real, whole foods than tissue constantly bombarded by chemical byproducts of food processing from something that came out of a box and went through a factory full of chemicals and processes I'd never even see or hear about.

Once snapped on, patrolling white blood recognize the snapped - on antibody as a signal of trouble, and release chemicals that call for more white blood cells to rush in and destroy the invader.

Chemicals are released that signal the system to slow down so it can have the time to work on the fat, which can take up to four hours or more.

Chronic inflammation occurs when your body receives on - going stress signals that activate the immune system to continue producing inflammatory chemicals.

Vitale Shreve, Kristyn R., Udell, Monique A.R., Stress, Security, and Scent: The influence of chemical signals on the social lives of domestic cats and implications for applied settings.