Sentences with phrase «on design factors»

That involves careful decisions on design factors both large and small.

Not exact matches

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.
In its findings on Tuesday, the NTSB said the self - driving system's «operational design» was a contributing factor to the 2016 crash because it allows drivers to avoid steering or watching the road for lengthy periods of time that were «inconsistent» with warnings from Tesla.
Even though you want to put your stamp on things, it's something of an unenviable task when you factor in the sheer amount of time and money spent, especially if you're a bit clueless about design.
Note: Yelp's search results are based on an algorithm that is designed to provide the best results based on a number of different factors including review text, ratings, and number of reviews.
They attribute the sticker shock to two factors: first, there is a proliferation of Web - design freelancers and moonlighters who offer their services at bargain prices on job exchanges like eLance.com; second, some huge companies have run ad campaigns claiming they can build a legit Web presence for a low starting cost.
Before you rely on marketing automation to solve your checkout issues, take a closer look at factors leading up to checkout and evaluate the design of your purchase flow:
Use the seven factors above to analyze and design your next strategic thinking session before you start spending extra time on tasks and projects that might have an overall negative net impact on your goals.
The parties blame that delay on factors including design changes requested by SBB to address complaints from associations for the disabled, as well as technical requirements related to the unique Gotthard Tunnel that required the car bodies to be redesigned.
The popular design trend may project a certain cool factor but the lack of privacy can be hard on employees trying to get work done, research suggests.
[16:00] Pain + reflection = progress [16:30] Creating a meritocracy to draw the best out of everybody [18:30] How to raise your probability of being right [18:50] Why we are conditioned to need to be right [19:30] The neuroscience factor [19:50] The habitual and environmental factor [20:20] How to get to the other side [21:20] Great collective decision - making [21:50] The 5 things you need to be successful [21:55] Create audacious goals [22:15] Why you need problems [22:25] Diagnose the problems to determine the root causes [22:50] Determine the design for what you will do about the root causes [23:00] Decide to work with people who are strong where you are weak [23:15] Push through to results [23:20] The loop of success [24:15] Ray's new instinctual approach to failure [24:40] Tony's ritual after every event [25:30] The review that changed Ray's outlook on leadership [27:30] Creating new policies based on fairness and truth [28:00] What people are missing about Ray's culture [29:30] Creating meaningful work and meaningful relationships [30:15] The importance of radical honesty [30:50] Thoughtful disagreement [32:10] Why it was the relationships that changed Ray's life [33:10] Ray's biggest weakness and how he overcame it [34:30] The jungle metaphor [36:00] The dot collector — deciding what to listen to [40:15] The wanting of meritocratic decision - making [41:40] How to see bubbles and busts [42:40] Productivity [43:00] Where we are in the cycle [43:40] What the Fed will do [44:05] We are late in the long - term debt cycle [44:30] Long - term debt is going to be squeezing us [45:00] We have 2 economies [45:30] This year is very similar to 1937 [46:10] The top tenth of the top 1 % of wealth = bottom 90 % combined [46:25] How this creates populism [47:00] The economy for the bottom 60 % isn't growing [48:20] If you look at averages, the country is in a bind [49:10] What are the overarching principles that bind us together?
Utilizing the «factor» test laid out in 506 (c), it seems that «reasonable steps to verify» for a member of a legitimate angel group would be less than that of a random person on the street, which is seemingly who the safe harbors appear to be designed for.
At Plato Web Design, we know how to maximize search engine optimization, or SEO, by improving your sites on - the - page and off - the - page factors.
One problem I've had with mint is that you can't (by design) link accounts on which you have two - factor auth.
Our chart above summarizes the major factors to focus on for search engine ranking success (and thanks to Column Five Media, for the infographic design).
The information allows Google to evaluate environmental factors in their offices and, in the future, make better decisions on workplace design to support employee wellbeing, productivity and creativity.
Fidelity Factor ETFs Choose from 8 commission - free funds designed to focus on specific investing goals.
«In order to cut through the preconceived wisdoms about which workplace design factors have the greatest and least impact on productivity, we asked our respondents to rate a wide spectrum of factors that impact their productivity.
By design, communism negates the effects of greed through a mandatory distribution of resources and then relies heavily on extra-economic factors to prevent sloth from hindering production.
Complimentarians like Piper also believe that competence is a factor in relationships, but also that people are designed to maintain specific roles in relation to one another based on gender.
Gary Westlake, founder of design agency Purple Creative, along with Sarah Macaulay, global marketing manager, at Glenfiddich will draw on their personal experience to identify the key factors in creating a new visual identity for a long established brand, like Glenfiddich, the world's most awarded single malt whisky.
This research identified the three driving factors behind the machine's design — the requirement for a high output sealer within a small footprint and absolute minimal downtime on tool changes and maintenance.
The Sustainable Winegrowing Program's mission, vision and values best describe the combination of factors that motivated the California wine community to design, develop, implement and report on a comprehensive sustainability program.
When worn with the silver side out, the Reversible Mercurial Jacket reflects almost 40 to fifty percent more belonging to the sun's rays, than the absorbing black side.Stitching, which pertains on the quality, and suppleness which ties into the performance are essential design factors.
Studies have yielded mixed results, which may reflect study design, such as how breastfeeding was defined, relying on recall of feeding from prior years, and other factors.
The most common sleep - related risk factor identified was an infant being placed on a surface not designed for infant sleep.
Combined with data showing that a substantially higher percentage of hits to the helmets of youth players are to the side of the helmet - which the researchers attributed to a differences in the styles of play between the different age groups, as well as the fact that youth players have a tendancy to fall to the side when tackled - these factors may result in a youth player being more susceptible to impacting his head on the ground while being tackled than a high school or college player, knowledge, they said, that could aid in the design of better youth - specific football helmets.
A prospective, controlled study of the effect of breast milk on infection among low birth weight infants was conducted in India in 1981.18 Although the sample size was small, 62 infants, the study design was a randomized block design in which feeding schedules for breast milk or formula were randomly allocated within groups of infants that were determined to be relatively homogeneous with respect to factors predisposing to infection.
A number of model programs were unable to document program impacts on parenting and home environment factors that are predictive of children's early learning and development through control group designs.
Reminiscent of fresh snow or fluffy clouds, White Gift builds on the comfort factor by combining pure white with intricate tone on tone textures, to create a fresh easy to live with design, with a sense of cosy style and timeless appeal.
Reminiscent of fresh snow or fluffy clouds, the Izziwotnot gift range baby moses basket builds on the comfort factor by combining pure white with intricate tone on tone textures, to create a fresh easy to live with design, with a sense of cosy style and timeless appeal.
«A lot of VR, people today can not tolerate,» says Kay Stanney, a human factors engineer with a focus on VR at Design Interactive in Orlando, Fla..
This will influence how they are cleaned, how they take on designs, and other factors.
But this outcome is not a given and depends on a variety of factors that can impact black carbon emissions such as engine design, fuel composition and geographic location.
To design the study, he combined these two elements with the long - time focus of Horvath's lab on STAT3, which has been implicated in cancer in general, as both a causative agent and a survival factor.
In 1982 results came in from the Multiple Risk Factors Intervention Trial, which was designed to reduce the risk of coronary heart disease by counseling an experimental group to stop smoking, lower their blood pressure and cut back on saturated fat.
Although this study represents only a single case, it provides unprecedented detail on the host response to Ebola virus disease and may inform the development of therapeutics designed to boost or accelerate host factors that most effectively counter the virus and promote healing.
«By examining multiple factors that affect tie formation and dissolution over time on Twitter, we've discovered information that could help technologists design and build tools that help users grow their audiences.»
Combining some of these data with several reliable public health data sources on asthma and using a survey designed to collect information on relevant risk factors, they were able to investigate the presence of any links between BCG vaccination and asthma with a high degree of accuracy.
«The discordant twin design minimizes a number of potentially confounding factors that may explain the association between childhood verbal ability and subsequent alcohol use by «controlling» for differences on variables [such as] socioeconomic differences or family factors that, if excluded, could cloud the interpretation of findings.»
Lowering prices, but at a cost Older wind turbines typically have not been equipped or designed to support voltage levels on power lines, a critical stability factor, and weren't required to provide that service.
If you've signed the San Francisco Declaration on Research Assessment (http://am.ascb.org/dora/), or you just don't think a metric designed for a journal should be used to evaluate individual scientists, avert your eyes: Journal impact factor has a strong influence on a scientist's probability of attaining PI - ship.
The group's work is based on «a carefully designed questionnaire and an empirical analysis of its data to determine the main factors influencing NEV purchases,» explained Hao.
In the largest conservation organizations, she explains, scientists design projects on the macro level — as if the map contained only natural features — and factor in culture afterward.
The researchers believe this model could be used for creating efficient building design and for retrofit analysis as it takes into account factors such as building orientation, building envelop material, shading and control on heating and cooling.
«To understand the factors behind T - cell - receptor binding to peptides will have major impact on biomedical developments, including vaccine design and immunotherapy.»
Computer simulation experiments will be designed to investigate the effects of key factors on RS efficiencies such as heritability, crossing schemes including male - sterility - facilitated and manual crossing, selection intensity, etc..
These and other ethical, legal and social challenges need to be considered when designing and conducting genomic research on host factors and host - vector - pathogen interactions in Ebola virus disease.
His team identified a factor that may be important for clinical trial design: progesterone was not toxic to all glioblastoma cell lines, and its toxicity may depend on whether the tumor suppressor gene p53 is mutated.
An ongoing project begun in 1985, CARDIA was designed to assess the long - term impact of various factors on the development of coronary artery disease.
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