That involves careful decisions
on design factors both large and small.
Not exact matches
These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial
designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed
on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk
Factors» in the company's most recent Annual Report
on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available
on the SEC's website at www.sec.gov.
In its findings
on Tuesday, the NTSB said the self - driving system's «operational
design» was a contributing
factor to the 2016 crash because it allows drivers to avoid steering or watching the road for lengthy periods of time that were «inconsistent» with warnings from Tesla.
Even though you want to put your stamp
on things, it's something of an unenviable task when you
factor in the sheer amount of time and money spent, especially if you're a bit clueless about
design.
Note: Yelp's search results are based
on an algorithm that is
designed to provide the best results based
on a number of different
factors including review text, ratings, and number of reviews.
They attribute the sticker shock to two
factors: first, there is a proliferation of Web -
design freelancers and moonlighters who offer their services at bargain prices
on job exchanges like eLance.com; second, some huge companies have run ad campaigns claiming they can build a legit Web presence for a low starting cost.
Before you rely
on marketing automation to solve your checkout issues, take a closer look at
factors leading up to checkout and evaluate the
design of your purchase flow:
Use the seven
factors above to analyze and
design your next strategic thinking session before you start spending extra time
on tasks and projects that might have an overall negative net impact
on your goals.
The parties blame that delay
on factors including
design changes requested by SBB to address complaints from associations for the disabled, as well as technical requirements related to the unique Gotthard Tunnel that required the car bodies to be redesigned.
The popular
design trend may project a certain cool
factor but the lack of privacy can be hard
on employees trying to get work done, research suggests.
[16:00] Pain + reflection = progress [16:30] Creating a meritocracy to draw the best out of everybody [18:30] How to raise your probability of being right [18:50] Why we are conditioned to need to be right [19:30] The neuroscience
factor [19:50] The habitual and environmental
factor [20:20] How to get to the other side [21:20] Great collective decision - making [21:50] The 5 things you need to be successful [21:55] Create audacious goals [22:15] Why you need problems [22:25] Diagnose the problems to determine the root causes [22:50] Determine the
design for what you will do about the root causes [23:00] Decide to work with people who are strong where you are weak [23:15] Push through to results [23:20] The loop of success [24:15] Ray's new instinctual approach to failure [24:40] Tony's ritual after every event [25:30] The review that changed Ray's outlook
on leadership [27:30] Creating new policies based
on fairness and truth [28:00] What people are missing about Ray's culture [29:30] Creating meaningful work and meaningful relationships [30:15] The importance of radical honesty [30:50] Thoughtful disagreement [32:10] Why it was the relationships that changed Ray's life [33:10] Ray's biggest weakness and how he overcame it [34:30] The jungle metaphor [36:00] The dot collector — deciding what to listen to [40:15] The wanting of meritocratic decision - making [41:40] How to see bubbles and busts [42:40] Productivity [43:00] Where we are in the cycle [43:40] What the Fed will do [44:05] We are late in the long - term debt cycle [44:30] Long - term debt is going to be squeezing us [45:00] We have 2 economies [45:30] This year is very similar to 1937 [46:10] The top tenth of the top 1 % of wealth = bottom 90 % combined [46:25] How this creates populism [47:00] The economy for the bottom 60 % isn't growing [48:20] If you look at averages, the country is in a bind [49:10] What are the overarching principles that bind us together?
Utilizing the «
factor» test laid out in 506 (c), it seems that «reasonable steps to verify» for a member of a legitimate angel group would be less than that of a random person
on the street, which is seemingly who the safe harbors appear to be
designed for.
At Plato Web
Design, we know how to maximize search engine optimization, or SEO, by improving your sites
on - the - page and off - the - page
factors.
One problem I've had with mint is that you can't (by
design) link accounts
on which you have two -
factor auth.
Our chart above summarizes the major
factors to focus
on for search engine ranking success (and thanks to Column Five Media, for the infographic
design).
The information allows Google to evaluate environmental
factors in their offices and, in the future, make better decisions
on workplace
design to support employee wellbeing, productivity and creativity.
Fidelity
Factor ETFs Choose from 8 commission - free funds
designed to focus
on specific investing goals.
«In order to cut through the preconceived wisdoms about which workplace
design factors have the greatest and least impact
on productivity, we asked our respondents to rate a wide spectrum of
factors that impact their productivity.
By
design, communism negates the effects of greed through a mandatory distribution of resources and then relies heavily
on extra-economic
factors to prevent sloth from hindering production.
Complimentarians like Piper also believe that competence is a
factor in relationships, but also that people are
designed to maintain specific roles in relation to one another based
on gender.
Gary Westlake, founder of
design agency Purple Creative, along with Sarah Macaulay, global marketing manager, at Glenfiddich will draw
on their personal experience to identify the key
factors in creating a new visual identity for a long established brand, like Glenfiddich, the world's most awarded single malt whisky.
This research identified the three driving
factors behind the machine's
design — the requirement for a high output sealer within a small footprint and absolute minimal downtime
on tool changes and maintenance.
The Sustainable Winegrowing Program's mission, vision and values best describe the combination of
factors that motivated the California wine community to
design, develop, implement and report
on a comprehensive sustainability program.
When worn with the silver side out, the Reversible Mercurial Jacket reflects almost 40 to fifty percent more belonging to the sun's rays, than the absorbing black side.Stitching, which pertains
on the quality, and suppleness which ties into the performance are essential
design factors.
Studies have yielded mixed results, which may reflect study
design, such as how breastfeeding was defined, relying
on recall of feeding from prior years, and other
factors.
The most common sleep - related risk
factor identified was an infant being placed
on a surface not
designed for infant sleep.
Combined with data showing that a substantially higher percentage of hits to the helmets of youth players are to the side of the helmet - which the researchers attributed to a differences in the styles of play between the different age groups, as well as the fact that youth players have a tendancy to fall to the side when tackled - these
factors may result in a youth player being more susceptible to impacting his head
on the ground while being tackled than a high school or college player, knowledge, they said, that could aid in the
design of better youth - specific football helmets.
A prospective, controlled study of the effect of breast milk
on infection among low birth weight infants was conducted in India in 1981.18 Although the sample size was small, 62 infants, the study
design was a randomized block
design in which feeding schedules for breast milk or formula were randomly allocated within groups of infants that were determined to be relatively homogeneous with respect to
factors predisposing to infection.
A number of model programs were unable to document program impacts
on parenting and home environment
factors that are predictive of children's early learning and development through control group
designs.
Reminiscent of fresh snow or fluffy clouds, White Gift builds
on the comfort
factor by combining pure white with intricate tone
on tone textures, to create a fresh easy to live with
design, with a sense of cosy style and timeless appeal.
Reminiscent of fresh snow or fluffy clouds, the Izziwotnot gift range baby moses basket builds
on the comfort
factor by combining pure white with intricate tone
on tone textures, to create a fresh easy to live with
design, with a sense of cosy style and timeless appeal.
«A lot of VR, people today can not tolerate,» says Kay Stanney, a human
factors engineer with a focus
on VR at
Design Interactive in Orlando, Fla..
This will influence how they are cleaned, how they take
on designs, and other
factors.
But this outcome is not a given and depends
on a variety of
factors that can impact black carbon emissions such as engine
design, fuel composition and geographic location.
To
design the study, he combined these two elements with the long - time focus of Horvath's lab
on STAT3, which has been implicated in cancer in general, as both a causative agent and a survival
factor.
In 1982 results came in from the Multiple Risk
Factors Intervention Trial, which was
designed to reduce the risk of coronary heart disease by counseling an experimental group to stop smoking, lower their blood pressure and cut back
on saturated fat.
Although this study represents only a single case, it provides unprecedented detail
on the host response to Ebola virus disease and may inform the development of therapeutics
designed to boost or accelerate host
factors that most effectively counter the virus and promote healing.
«By examining multiple
factors that affect tie formation and dissolution over time
on Twitter, we've discovered information that could help technologists
design and build tools that help users grow their audiences.»
Combining some of these data with several reliable public health data sources
on asthma and using a survey
designed to collect information
on relevant risk
factors, they were able to investigate the presence of any links between BCG vaccination and asthma with a high degree of accuracy.
«The discordant twin
design minimizes a number of potentially confounding
factors that may explain the association between childhood verbal ability and subsequent alcohol use by «controlling» for differences
on variables [such as] socioeconomic differences or family
factors that, if excluded, could cloud the interpretation of findings.»
Lowering prices, but at a cost Older wind turbines typically have not been equipped or
designed to support voltage levels
on power lines, a critical stability
factor, and weren't required to provide that service.
If you've signed the San Francisco Declaration
on Research Assessment (http://am.ascb.org/dora/), or you just don't think a metric
designed for a journal should be used to evaluate individual scientists, avert your eyes: Journal impact
factor has a strong influence
on a scientist's probability of attaining PI - ship.
The group's work is based
on «a carefully
designed questionnaire and an empirical analysis of its data to determine the main
factors influencing NEV purchases,» explained Hao.
In the largest conservation organizations, she explains, scientists
design projects
on the macro level — as if the map contained only natural features — and
factor in culture afterward.
The researchers believe this model could be used for creating efficient building
design and for retrofit analysis as it takes into account
factors such as building orientation, building envelop material, shading and control
on heating and cooling.
«To understand the
factors behind T - cell - receptor binding to peptides will have major impact
on biomedical developments, including vaccine
design and immunotherapy.»
Computer simulation experiments will be
designed to investigate the effects of key
factors on RS efficiencies such as heritability, crossing schemes including male - sterility - facilitated and manual crossing, selection intensity, etc..
These and other ethical, legal and social challenges need to be considered when
designing and conducting genomic research
on host
factors and host - vector - pathogen interactions in Ebola virus disease.
His team identified a
factor that may be important for clinical trial
design: progesterone was not toxic to all glioblastoma cell lines, and its toxicity may depend
on whether the tumor suppressor gene p53 is mutated.
An ongoing project begun in 1985, CARDIA was
designed to assess the long - term impact of various
factors on the development of coronary artery disease.