Sentences with phrase «on different cancers»

By understanding the context of a cell, we may identify compounds that work selectively on different cancers.

Dr Bhaskaran explained, «There was a lot of variation in the effects of BMI on different cancers.

Further studies of the Cyclin D1 protein on different cancer tissues are recommended.

Not exact matches

«In the long term, we want to be able to send energy to and communicate with implants all over the body, to record data from a variety of organs in many different ways, maybe even report on the conditions of tumors or cancer therapies,» Maharbiz says.

They're really heavily intertwined with our metabolism and have an enormous impact on our processing of food and on our health and disease and they've been linked to many different diseases to obesity, to diabetes, to heart disease, and even to cancer and Urological disease.

The drug may soon find a wider market if it can be shown effective in treating lymphoma and other blood cancers, and the price for those indications may well be different, based on their if value story.

We're also making progress on our liquid biopsy program since our last update, including the recently announced collaboration with Memorial Sloan Kettering Cancer Center, which is focused on furthering the basic understanding of the biology of circulating tumor DNA, or ctDNA, in different cancer Cancer Center, which is focused on furthering the basic understanding of the biology of circulating tumor DNA, or ctDNA, in different cancer cancer types.

It is blatantly clear why scientists employed by the tobacco industry arrive at quite different conclusions on the relation of smoking and cancer than do others.

He went on a mission to play 9 different positions in five different spring training games to raise money for cancer and ended up playing for all ten teams.

«My auntie died from cancer and on her last day she said, «I've worked every day with the plan of stopping one day and doing all these different things, and then I ran out of time.»

Studies done with animals show that acrylamide in the diet increases the risk of developing several different types of cancer, including stomach and colon cancer and don't get me started on the salt levels.

Challenges highlighted for the year ahead were: Moving forward on piloting flexible sigmoidoscopy bowel screening; a national awareness campaign on bowel cancer; improving diagnostic capacity and productivity; the needs of survivors in different post-treatment phases; providing information to commissioners and providers about patients» experience of care; giving support to tackle issues such as information provision and better communication.

«These are early results completed on three different types of cancer and we accept that more research needs to be done; but these results so far are remarkable,» said Professor Anderson.

Last summer, Italian and Dutch groups separately published papers suggesting that children are at wildly different risks for cancer depending on which defect they carry — with the risk ranging from less than 3 % to about 25 % — and argued that for lower - risk children, screening might not make sense.

«We can use different approaches to reverse methylation,» she says, «turning silenced genes back on, and seeing whether we can prevent the tumours from occurring or treat the cancer after it has appeared.»

Eight years ago, developmental biologist Rita Fior learned that her mother, who needed cancer treatment at the time, would receive different drugs depending on nothing more than which hospital she chose.

Qin; her mentor Elisa V. Bandera, MD, PhD, professor of epidemiology at Rutgers Cancer Institute of New Jersey; and fellow researchers evaluated the impact of three index - based dietary patterns: the 2005 Healthy Eating Index (HEI - 2005), which was based on the federal Dietary Guidelines for Americans; the 2010 Healthy Eating Index (HEI - 2010), which reflects the most recent dietary guidelines and has an increased emphasis on quality; and the Alternate Healthy Eating Index - 2010 (AHEI - 2010), which is based on a different nutrition guide, the Healthy Eating Pyramid.

Soon after she arrived, she ran an experiment on six different thyroid cancer lines, but her results came back impossibly clean: Three lines gave one identical result, and the other three gave another identical result.

Research based on such false cell lines would undermine the understanding of different cancers and possible treatments, and clutter the scientific literature with bogus conclusions.

She has described the impact that different estrogen receptors have on breast, pancreatic, and colorectal cancer, including transcriptomic effects involving long noncoding RNAs and microRNAs.

In a related study, published online on March 27 in the same journal, Green's group also showed that a different particle formulation could effectively carry and deliver so - called siRNAs to brain cancer cells.

The research of different types of cancer and the testing of new treatments depends on accurate mouse models.

The researchers have isolated the sesquiterpene lactone damsin from the plant and studied its effect on cancer stem cells in three different breast cancer cell lines.

In fact, depending on the tumor cell, they grow at dramatically different speeds, according to a study led by Nicholas Navin, Ph.D., assistant professor in the Department of Genetics at The University of Texas M.D. Anderson Cancer Center in Houston.

The team used five types of antibiotics — including one used to treat acne (doxycycline)-- on cell lines of eight different types of tumour and found that four of them eradicated the cancer stem cells in every test.

New research on bowel cancer has shown that every tumour is different, and that every cell within the tumour is also genetically unique.

When Kaufman, Zon and colleagues looked to see what was different about these early cancer cells, they found that crestin and the other activated genes are the same ones turned on during zebrafish embryonic development — specifically, in the stem cells that give rise to the pigment cells known as melanocytes, within a structure called the neural crest.

They found that the number of copies of lncRNA genes on a chromosome consistently change in 12 different cancer types and lncRNA genes are widely expressed in cancer cells.

A search of the CRISP database of NIH - funded research projects on three key words — mutant, androgen, and receptor — yields 24 projects funded since 1999 by nine different NIH institutes: the National Cancer Institute (eight projects), the National Institute of General Medical Sciences (NIGMS, three projects), the National Institute of Child Health and Human Development (three projects), the National Institute of Diabetes and Digestive and Kidney Diseases (two projects), and the National Center for Research Resources (two projects).

This variation tells us that BMI must affect cancer risk through a number of different processes, depending on the cancer type.»

The team worked on tissue from three patients with colorectal cancer, taking normal bowel stem cells and cells from four different areas of the tumours.

The resulting «map» of gene - drug interactions allowed the researchers to accurately predict the responses of multiple human cancer cell lines to different chemotherapy agents based on the cell lines» genetic profiles and also revealed new genetic factors that appear to determine the response of breast and ovarian tumor cells to common classes of chemotherapy treatment.

He said: «The impact of different types of red meat and dietary patterns on cancer locations is one of the biggest challenges in the study of diet and colorectal cancer.

A similar idea involves injecting cancer patients with strains of different bacteria that have been genetically modified to present antigens found on pancreatic cancer cells.

«This study not only represents a longstanding collaboration between the University of Utah and UCSF but also is a reflection of the transition in research from single investigators working on their own to highly collaborative studies with experts in many fields from different institutions,» says Mulvihill, who is also a pancreatic cancer surgeon and an investigator with the University of Utah's Huntsman Cancer Instcancer surgeon and an investigator with the University of Utah's Huntsman Cancer InstCancer Institute.

Surprisingly, they found that although the patterns of gene expression — as shown by the RNA sequencing — differed between the hepatocellular carcinomas and the liver cancers with biliary phenotype and depended on the histological type, the overall pattern of mutations in the cells was actually similar between the tumors — of either type — that had emerged in patients who had had infections with either hepatitis C or B, and were different in patients without such infections.

«So perhaps in this age of cancer genomics showing how diverse and heterogenous human cancer is, we should be focusing on the common effects that different mutations lead to,» he says.

The method is based on the knowledge that different tumors can be driven by different subsets of cancer genes.

«Although right now we are focusing on developing a cancer vaccine, in the future we could be able to manipulate which type of dendritic cells or other types of immune cells are recruited to the 3D scaffold by using different kinds of cytokines released from the MSRs,» said co-lead author Aileen Li, a graduate student pursuing her Ph.D. in bioengineering at Harvard SEAS.

In the new study, the researchers cultured mouse skin - cancer colonies on various 2 - D and 3 - D environments of different shapes and patterns to see if the tumor shape contributes to activation of cancer stem cells, and to see where in the tumor the stem cells appeared.

On the other hand, many studies conclude that appropriate carotenoid levels in the diet can play a positive role in protecting against ocular and cardiovascular diseases and different types of cancer, among others.

«The focus of chemotherapy and existing standard - of - care is on killing cancer cells but instead we took a completely different approach which changes the environment the cancer cells live in,» said Mick Bhatia, director and senior scientist with the McMaster Stem Cell and Cancer Research Institute, who led the group that performed the cancer cells but instead we took a completely different approach which changes the environment the cancer cells live in,» said Mick Bhatia, director and senior scientist with the McMaster Stem Cell and Cancer Research Institute, who led the group that performed the cancer cells live in,» said Mick Bhatia, director and senior scientist with the McMaster Stem Cell and Cancer Research Institute, who led the group that performed the Cancer Research Institute, who led the group that performed the study.

These cells have different factors on their surfaces which determines how «sticky» the cells are and whether they are responsible for mediating the cancer cells binding to the blood vessel walls.

«That there are a number of clinical trials on - going in a range of different cancers is an encouraging start.»

The idea is that the drug, being within the nano - hydrogels, is transported directly to cancer cells where it can be released without damaging other parts of the body, because hydrogels offer the possibility of dosing a myriad of active substances on the site desired and can be administered as dry or swollen hydrogels by different routes: oral, nasal, buccal, rectal, transdermal, vaginal, ocular and parental.

«Having these personalized laboratory models, which we can make in a matter of weeks, will let us test multiple different drugs on the tumor and help us bring precision medicine to individuals with bladder cancer.»

Perhaps shedding light on this mystery, the researchers found three different types of mutations in the estrogen receptor in patients whose cancer was resistant to anti-hormone therapy.

Geneticists have so far concentrated on genes that are linked to disease: first the simple but rare inherited diseases like cystic fibrosis (the gene for which is on chromosome 7) or Huntington's (chromosome 4), then the environmental diseases for which different people inherit different susceptibilities, such as Alzheimer's (chromosome 19) or breast cancer (chromosomes 13 and 17).

The ManCou multicolored fluorescent probe glows different colors and different intensities depending on a cancer cell's type and malignancy.

Depending on the type of tissue, it plays different protective and mechanical roles, but it has also been shown to be involved in a number of diseases, including the growth of cancer tumors.