Dr. Anju Vasudevan's work
on early embryogenesis of the forebrain vascular system has opened up an entirely new conceptual framework from which to view this important component of brain development.
Not exact matches
In order to elucidate the significance of
early epigenetic modifications
on the development of neural cells during
embryogenesis in the mouse, Götz and her colleagues specifically inactivated the gene Uhrf1.
When they had a closer look into the embryos, the team found that several important developmental genes that are normally switched off during
early embryogenesis were turned
on in embryos without H3K27me3.
«Our focus here has been
on early heart development, but the basic principles of patterning of human pluripotent stem cells, and subsequently differentiating them, can be readily expanded into a broad range of tissues for understanding
embryogenesis and tissue morphogenesis,» said Healy.
«Our focus here has been
on early heart development, but the basic principles of patterning of human pluripotent stem cells, and subsequently differentiating them, can be readily expanded into a broad range of tissues for understanding
embryogenesis and tissue morphogenesis,» said Dr. Healy.
Antonio Giraldez (Yale University)-- A developmental biologist, Dr. Giraldez works
on deciphering the regulatory code that shapes
embryogenesis, the
earliest events that occur after fertilization.
The data show that the presence of a modification of an evolutionary conserved structure, such as the presence of a rib
on the seventh vertebra (a cervical rib, i.e. a change in the number of cervical vertebrae), can be used as a reliable indicator of disturbances of
early embryogenesis (Collaboration with Liliane Wijnaendts, Free University Medical Centre (VUMC).
Whitehead Institute researchers have determined that poly (A) tails
on messenger RNAs (mRNAs) shift their role in the regulation of protein production during
early embryogenesis.