Sentences with phrase «on effect estimates»

Research to quantify the influence of industry sponsorship on effect estimates can be improved by obtaining complete and accurate data on sponsors of research and conflicts of interest of sponsors and authors, and focusing on specific research questions and study designs.

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

Putting together a galactic - scale blockbuster is a global effort, involving not only this visual effects shop — Shore estimates his team is responsible for 250 of the shots cinema - goers will see once Star Wars Episode VII opens on Dec. 18 — but also ILM's head office in San Francisco, as well as branches in London and Singapore.

If current estimates are correct that the leakage rate is around 3 percent, then we calculated that switching all coal plants to average - efficiency natural gas plants would have little effect on the power sector's contribution to climate change.

«On the corporate side, we disregard the temporary increase in tax payments in 2018 related to the tax on deemed repatriation; we do not estimate a growth effect from those repatriated profits, either,» the note saiOn the corporate side, we disregard the temporary increase in tax payments in 2018 related to the tax on deemed repatriation; we do not estimate a growth effect from those repatriated profits, either,» the note saion deemed repatriation; we do not estimate a growth effect from those repatriated profits, either,» the note said.

Adjustments to provisional estimates for the income tax effects related to the tax reform law enacted on December 22, 2017 (Tax Reform Law)

Street estimates finally look safe while Y / Y compares on iPhone units and overall AAPL revenue are bottoming in [calendar] Q1 and should turn flat to up as soon as [calendar] Q4 additionally fueled by less severe [currency exchange] headwinds... iPhone 7 will benefit if nothing else from the 6/6 + «echo» effect as these units enter the upgrade base, OLED in ’17 solves growth concerns and builds a bridge to new «dreamy» form factors.

Earnings before interest, taxes and one - time items rose 20 % to 4.13 billion kroner ($ 652 million), beating estimates of 3.82 billion kroner Sales rose 2 % on a basis that excludes currency and acquisition effects, compared with analysts projections for growth of 3.2 % Debt reduced by 14 % to 21.9 billion kroner Carlsberg reduced its full - year forecast for gains from currency shifts to 50 million kroner from 300 million kroner.

It could also have a ripple effect on other types of substance abuse, since an estimated 80 % of new heroin users start with prescription opioids such as OxyContin — a statistic that may have contributed to the decline in prescriptions in the first place.

Earnings estimates for the 2018 fiscal year are being revised upwards by some analysts to account for the impending bump from recent interest rate hikes and a U.S. corporate tax cut from 35 per cent to 21 per cent that took effect on Jan. 1.

It added that «the effect on U.S. growth is estimated to be positive through 2020, cumulating to 1.2 percent through that year, with a range of uncertainty around this central scenario.»

The Congressional Budget Office and the staff of the Joint Committee on Taxation (JCT) have completed an estimate of the direct spending and revenue effects of the Better Care Reconciliation Act of 2017, a Senate amendment in the nature of a substitute to H.R. 1628.

This assertion had three components: (1) The commenter estimated the cost over 60 days to be $ 250 million based on the on - going cost from the final 2016 RIA of $ 1.5 billion per year, (2) that cost savings over a 10 - year period were not provided to allow comparison to the negative effects on investors that would occur over the ten year period, (3) that industry cost savings were not projected out over 10 years using returns on capital in a similar manner to investors» lost earnings.

Including just the effects of economic feedback from deficit reduction would reduce the cumulative deficit over the next 10 years by roughly $ 160 billion — or about 0.1 percent of GDP, on average — compared with CBO and JCT's conventional estimate of the President's proposals.

It is true that predicting effects on market premiums is hard — but the 10 percent estimate by CBO is as likely to be low as it is to be high.

A day earlier the American Petroleum Institute had estimated crude oil inventories had risen for the second week in a row, by a hefty 6.18 million barrels, which was only to be expected as the market is prepared for the Hurricane Harvey effects on Gulf Coast refining to linger for another few weeks.

Of nearly 2,700 employers surveyed, 41 % estimate a single bad hire cost $ 25,000; a quarter estimate a bad choice cost $ 50,000 or more — not to mention the demoralizing effect of the issue on other employees and on the new hire.

It may be surprising that including estimated foreign GVA has so little effect on our conclusions about overvaluation here.

To illustrate the magnitude of this, we can estimate the effects of a 100 basis point reduction in the cash rate on net interest payments (as a share of household disposable incomes; Graph 6).

As a share of total household sector disposable income, the cash flow effect in this scenario is estimated be less than 0.2 per cent on average per annum over each of the next three years (Graph 7).

The rule, which was issued on Thursday and which the Labor Department estimates will directly affect more than 1.1 million people once fully in effect, enables workers to accrue up to seven days of paid sick leave a year.

This estimate ignores the budget's claimed economic growth effects; it is difficult to determine what debt would be when counting economic effects based on the information given.

in the case of our directors, officers, and security holders, (i) the receipt by the locked - up party from us of shares of Class A common stock or Class B common stock upon (A) the exercise or settlement of stock options or RSUs granted under a stock incentive plan or other equity award plan described in this prospectus or (B) the exercise of warrants outstanding and which are described in this prospectus, or (ii) the transfer of shares of Class A common stock, Class B common stock, or any securities convertible into Class A common stock or Class B common stock upon a vesting or settlement event of our securities or upon the exercise of options or warrants to purchase our securities on a «cashless» or «net exercise» basis to the extent permitted by the instruments representing such options or warrants (and any transfer to us necessary to generate such amount of cash needed for the payment of taxes, including estimated taxes, due as a result of such vesting or exercise whether by means of a «net settlement» or otherwise) so long as such «cashless exercise» or «net exercise» is effected solely by the surrender of outstanding stock options or warrants (or the Class A common stock or Class B common stock issuable upon the exercise thereof) to us and our cancellation of all or a portion thereof to pay the exercise price or withholding tax and remittance obligations, provided that in the case of (i), the shares received upon such exercise or settlement are subject to the restrictions set forth above, and provided further that in the case of (ii), any filings under Section 16 (a) of the Exchange Act, or any other public filing or disclosure of such transfer by or on behalf of the locked - up party, shall clearly indicate in the footnotes thereto that such transfer of shares or securities was solely to us pursuant to the circumstances described in this bullet point;

Current numbers suggest the Eagle Ford also is growing, though the Fed reports that estimates may be revised downward on the effects of Harvey as more data becomes available.

Valuation — with regards to valuation of the company at $ 240 per share, this includes valuing the business at $ 216 per share (at 18x our FY 2016 earnings estimate of $ 12 per share) plus net cash per share of $ 24 ($ 150 billion of net cash less the tax effect on international cash for repatriation, which we estimate to ultimately be 6 %, and for simplicity purposes, apply to all cash on balance sheet rather than just the international cash).

In addition, any change in these estimates or their related assumptions could have an adverse effect on our operating results.

The changes wrought by the proposed legislation will have a much bigger effect on some groups — especially those who get insurance through their employers and those on Medicaid — than estimated by recent analysis from independent healthcare policy experts such as the Brookings Institution and credit rating agency S&P Global Ratings

Deutsche Bank revised similarly, cutting its earnings estimates for 2017 by $ 1 billion, adding that «this could have a longer term effect on valuation.»

A surge in Australia's terms of trade has mitigated the effect of these developments on the trade deficit, which is estimated to have been around 3 1/4 per cent of GDP in the December quarter 2004, wider than at mid year but broadly similar to the outturns of the past year and a half (Graph 32).

Preliminary indications are that the implementation of the tax changes on 1 July proceeded smoothly and that the net tax effects on prices were broadly in line with (or possibly slightly lower than) those suggested by prior estimates.

Thus, the conduct of monetary policy in coming quarters will require careful interpretation of the data on price developments and assessment of the various estimates of the net tax effect on prices that are available.

Trans Mountain identified the WTP [Westridge Tunnel Portal] site as a priority for the Project and indicated that approval by 15 February 2018 would allow sufficient time for the WTP site clearing activities, estimated to take four to six weeks, to be completed prior to the migratory bird restrictions which come into effect on 26 March 2018.

And the estimated effect on the auto sector will be the loss of 24,000 jobs.

Tax cuts always effect assets prices, regulations are estimated to account for up to 35 % of building new construction costs for homes in some locations and though federal deregulation may not impact local regulations as much it does have a multiplier effect on the economy just like a tax cut does and anticipation of an infrastructure plan the scale of this administration's, though it hasn't been passed, would also have an anticipatory effect on leading indicators like stocks and other commodities that raise costs, which we have already seen.

These seniors will soon be joining the 43 million Americans working to repay an estimated $ 1.3 trillion in student debt.The student loan debt problem has a lasting effect on the lives of graduates long after «Pomp and Circumstance» signals the end of their college careers.

This assessment is based on the usual wide range of individual estimates, with some allowance made for the seasonal compositional effects that generally boost measured median prices in the December quarter and weigh on the March quarter reading.

Analyst Jamie Baker also cited pending cost increases, estimating a 55 cent effect on earnings per share and 5 percentage - point boost in costs for each seat flown a mile next year from expected new employee contracts.

But as I noted last week (see Two Point Three Sigmas Above the Norm), nominal growth and interest rate variations have historically canceled out over the past century, with little effect on the accuracy of our valuation estimates — matched reductions in the growth rate and the discount rate really don't affect fair value.

They see forests as having a beneficial effect on weather and agriculture, the value of which can hardly be estimated.

Using the conservative estimate that a vampire would only need to feed once a month, they are able to calculate the effect on the human race.

Although sales taxes on soft drinks in Ireland and France have both been associated with a reduction in consumption, the health effects have not been studied.15 16 No significant effect on obesity of US state sales taxes has been found, although the level of taxation there has probably been too low to affect health.13 17 The modelled estimates of the health effect of a 20 % sugar sweetened drink tax in the United States vary, but such a tax has been predicted to reduce obesity by up to three percentage points.13 18 The effect of a sugar sweetened drink tax in the UK has not, until now, been formally estimated.

Whereas estimates from the National Diet and Nutrition Survey and Living Costs and Food Survey are broadly comparable (123 mL / adult / day versus 168 mL / person / day), the British Soft Drinks Association's figures are threefold to fourfold higher.48 61 The level and pattern of consumption will determine the magnitude of the public health effects of a sugar sweetened drinks tax, as well as its effect on health inequalities.

In terms of own price elasticity values, a recent meta - analysis estimated an average own price effect for carbonated sugar sweetened drinks (a near equivalent of the category non-concentrated sugar sweetened drinks, which predominantly includes carbonated drinks) of − 0.93, larger than our value of − 0.81.51 Our estimated value is also at the lower end of the range of own price elasticities frequently cited for sugar sweetened drinks of − 0.8 to − 1.0, based on one large review.52 Our own price estimate is comparable to experimental data (a 25 % reduction for a 35 % price rise) in a canteen study.53 However, all these estimates may be influenced by US studies in which higher estimates may reflect higher levels of consumption.

We used the estimates generated to derive the change in energy intake, which we then used to model the effect on average body weight and prevalence of obesity in the UK (fig 1 ⇓).

In terms of effect on consumption, Ng et al estimated a reduction in sugar sweetened drink intake of 104 mL (10 %) per person per week compared with our predicted reduction of around 15 %.19 The substitution effects predicted in Ng et al's study are very slight, and as a result the predicted change in energy intake is larger (net decrease of 24 kJ / person / day compared with our estimate of 17 kJ / person / day).

The lower levels of baseline sugar sweetened drink consumption in the UK compared with the US may in part explain why the effect on obesity that we estimate in the UK is much less than that estimated in the US.12 The differences with respect to other modelling studies may also be partly explained by their use of higher own price elasticity values for sugar sweetened drinks than we have calculated and used here.18 22 52 We can not make direct comparisons between the results of our study and the results of recent studies of the effect of reducing sugar sweetened drink consumption on body weight in children, 5 7 as the relation between energy balance and change in body mass index in children who are growing is different from that in adults.

We chose to model the effects on body weight because good evidence (from both trials and epidemiological studies) links regular consumption of sugar sweetened drinks to weight gain.8 10 12 Moreover, data from longitudinal studies support the idea that changes in the price of sugar sweetened drinks are linked to changes in body weight.20 Other groups have used this form of modelling to estimate the effects of a sugar sweetened drink tax on obesity.18 21 22

In terms of substitution effects, the major difference between our estimates and those from the US is that our data indicate that diet soft drinks are a substitute for sugar sweetened drinks, whereas US data suggest that diet soft drinks are a complement (as the price of sugar sweetened drinks goes up, consumption of diet drinks goes down).18 22 This may explain why a US tax on sugar sweetened drinks has been so heavily resisted, as a «double whammy» on sales of both diet soft drinks and sugar sweetened drinks would occur.18.

Crop estimate reports are mixed in California and it remains to be seen what effects, if any, the draught will have on the coming crop.

Estimates of effects of traffic light labels and Health Star Rating labels compared with noninterpretive nutrition information panels on nutrient contents of packaged foods purchased during a 4 - wk intervention1