Figure 6 shows the effects of 75 µM kahweol
on endothelial cell migration, as determined by the «wound healing» assay, after 8 and 24 h of treatment.
Not exact matches
Like a free pass, its presence
on the surface of lymphoma
cells facilitates their
migration through the vessel walls between adjacent
endothelial cells.
Mechanotransduction The effects of extracellular matrix stiffening
on endothelial cell health Cynthia Reinhart - King, Cornell University The effects of membrane cholesterol and extracellular matrix elasticity
on vascular smooth muscle
cell mechanics and
migration Zhongkui Hong, University of South Dakota
They include its effects
on endothelial cell «differentiation» to yield tubular - like structures,
endothelial and tumor
cell proliferation, apoptosis, and
migration, as well as its effects
on extracellular matrix remodelling enzyme activities of matrix metalloproteinase - 2 (MMP - 2) and urokinase - type plasminogen activator (uPA).
We show for the first time that kahweol is an anti-angiogenic compound with inhibitory effects in two in vivo and one ex vivo angiogenesis models, with effects
on specific steps of the angiogenic process:
endothelial cell proliferation,
migration, invasion and tube formation
on Matrigel.